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Proper Citation: RRID:MGI:4940244
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased respiratory quotient, decreased liver weight, decreased susceptibility to hepatic steatosis, decreased total body fat amount, homeostasis/metabolism phenotype, small liver, decreased fat cell size, abnormal eating behavior, abnormal muscle regeneration, decreased circulating triglyceride level, decreased circulating free fatty acid level, decreased circulating cholesterol level, decreased body weight, abnormal locomotor activation, decreased abdominal fat pad weight, increased energy expenditure, decreased epididymal fat pad weight, abnormal gluconeogenesis, abnormal cellular respiration, decreased anxiety-related response, abnormal depression-related behavior, abnormal dendrite morphology, abnormal muscle development, increased circulating interleukin-6 level, increased susceptibility to endotoxin shock, increased tumor necrosis factor secretion, increased sensitivity to xenobiotic induced morbidity/mortality, increased interleukin-6 secretion, increased circulating tumor necrosis factor level, increased circulating interleukin-10 level, decreased susceptibility to diet-induced obesity, decreased susceptibility to age related obesity, abnormal myoblast differentiation, decreased myoblast proliferation, decreased skeletal muscle fiber size, decreased skeletal muscle fiber diameter
Affected Gene: Dusp1
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Source: MGI
Source Database: MGI, Mouse Genome Informatics MGI