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Proper Citation: RRID:MGI:3772339
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal circulating cholesterol level, increased susceptibility to atherosclerosis, increased circulating cholesterol level, increased grip strength, abnormal spatial learning, atherosclerotic lesions, increased susceptibility to atherosclerosis, abnormal circulating cholesterol level, abnormal fat pad morphology, abnormal triglyceride level, hyperglycemia, increased circulating insulin level, impaired glucose tolerance, hepatic steatosis, increased susceptibility to weight gain, decreased susceptibility to weight gain, hyperactivity, increased percent body fat/body weight, increased circulating VLDL triglyceride level, increased circulating VLDL cholesterol level, increased circulating cholesterol level, atherosclerotic lesions, abnormal CNS glial cell morphology, abnormal spatial working memory, increased circulating cholesterol level, increased circulating triglyceride level, increased circulating interleukin-1 beta level, amyloid beta deposits, abnormal astrocyte morphology, abnormal microglial cell morphology, increased circulating tumor necrosis factor level, increased circulating interleukin-6 level, increased liver triglyceride level, increased circulating triglyceride level, decreased circulating interleukin-10 level, increased circulating LDL cholesterol level, increased liver cholesterol level, increased circulating HDL cholesterol level, increased circulating LDL cholesterol level, increased circulating cholesterol level, increased circulating triglyceride level, decreased circulating HDL cholesterol level, increased susceptibility to atherosclerosis, increased circulating VLDL cholesterol level, increased susceptibility to atherosclerosis, hyperglycemia
Affected Gene: Ldlr
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No rating or validation information has been found for Ldlrtm1Her/Ldlrtm1Her.
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI