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Proper Citation: RRID:MGI:3760616
Description: Allele Detail: Spontaneous This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Spontaneous This is a legacy resource.
Phenotype: increased cellular sensitivity to X-ray irradiation, premature death, spleen hypoplasia, abnormal spleen white pulp morphology, abnormal response to transplant, thymus cysts, increased mean corpuscular volume, increased macrophage cell number, increased length of allograft survival, increased T cell derived lymphoma incidence, decreased CD4-positive, alpha beta T cell number, decreased lymphocyte cell number, decreased level of surface class I molecules, decreased immunoglobulin level, abnormal thymus lobule morphology, decreased CD8-positive, alpha-beta T cell number, increased T cell derived lymphoma incidence, spleen hypoplasia, premature death, decreased B cell number, decreased CD4-positive, alpha beta T cell number, decreased CD8-positive, alpha-beta T cell number, abnormal lymph node morphology, decreased erythrocyte cell number, decreased bone marrow cell number, decreased T cell number, decreased NK cell number, abnormal lymph node morphology, abnormal response to transplant, abnormal spleen white pulp morphology, decreased mature B cell number, abnormal thymus corticomedullary boundary morphology, increased granulocyte number, impaired complement classical pathway, homeostasis/metabolism phenotype, impaired natural killer cell mediated cytotoxicity, decreased pre-B cell number
Affected Gene: Prkdc
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
