URL: https://www.jax.org/strain/000664
Proper Citation: RRID:IMSR_JAX:000664
Description: Mus musculus with name C57BL/6J from IMSR.
Species: Mus musculus
Synonyms: B6. B6J. Black 6. C57 Black
Notes: gene symbol note: hemoglobin beta chain complex|arylalkylamine N-acetyltransferase|NLR family; pyrin domain containing 12|microwave induced increase in complement receptor B cells|cytochrome c oxidase subunit 7A2 like|gamma-aminobutyric acid type A receptor subunit alpha 2|MX dynamin-like GTPase 1|beta-2 microglobulin|nuclear encoded tRNA arginine 5 (anticodon TCT)|nicotinamide nucleotide transhydrogenase|purinergic receptor P2X; ligand-gated ion channel; 7|forebrain weight 1|CD5 antigen|glucose homeostasis QTL 3|aryl-hydrocarbon receptor|cadherin related 23 (otocadherin)|glucose homeostasis QTL 1|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|glucose homeostasis QTL 2|forebrain weight 2; inbred strain: Hbb|Aanat|Nlrp12|Micrl|Cox7a2l|Gabra2|Mx1|B2m|n-TRtct5|Nnt|P2rx7|Fbrwt1|Cd5|Gluchos3|Ahr|Cdh23|Gluchos1|Apobec3|Gluchos2|Fbrwt2
Affected Gene: hemoglobin beta chain complex|arylalkylamine N-acetyltransferase|NLR family; pyrin domain containing 12|microwave induced increase in complement receptor B cells|cytochrome c oxidase subunit 7A2 like|gamma-aminobutyric acid type A receptor subunit alpha 2|MX dynamin-like GTPase 1|beta-2 microglobulin|nuclear encoded tRNA arginine 5 (anticodon TCT)|nicotinamide nucleotide transhydrogenase|purinergic receptor P2X; ligand-gated ion channel; 7|forebrain weight 1|CD5 antigen|glucose homeostasis QTL 3|aryl-hydrocarbon receptor|cadherin related 23 (otocadherin)|glucose homeostasis QTL 1|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|glucose homeostasis QTL 2|forebrain weight 2
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No rating or validation information has been found for C57BL/6J.
Issue
Warning this mouse may be epileptogenic. The cause seems to be that the GABAA receptor is expressed at very low levels compared to other mouse strains including the C57BL/6N, according to Hawkins (2016) and Mulligan (2019).
Source: Integrated Animals
Source Database: International Mouse Resource Center IMSR, JAX