URL: https://web.expasy.org/cellosaurus/CVCL_0579
Proper Citation: Coriell Cat# AG06814-M, RRID:CVCL_0579
Description: Cell line WI-38 is a Finite cell line with a species of origin Homo sapiens (Human)
Sex: Female
Defining Citation: PMID:211143, PMID:352912, PMID:535915, PMID:656543, PMID:699332, PMID:1031681, PMID:1249414, PMID:1756776, PMID:3016668, PMID:4203458, PMID:4329447, PMID:4695793, PMID:4817727, PMID:5347639, PMID:5668122, PMID:5801069, PMID:5834207, PMID:5956336, PMID:6256643, PMID:6409440, PMID:6538202, PMID:6887978, PMID:7065527, PMID:7972006, PMID:14064953, PMID:14218592, PMID:14315085, PMID:17395773, PMID:17792436, PMID:19896956, PMID:20215515, PMID:22984048, PMID:25063771, PMID:25903999, PMID:29546209
Comments: Anecdotal: Have been flown in space on Skylab-3 to study growth in microgravity (PubMed=352912)., Anecdotal: Leonard Hayflick when numbering diploid cell strains 'jumped' directly from WI-27 (which failed) to WI-38 (CelloPub=CLPUB00391)., Senescence: Life expectancy of 50 +- 10 population doublings. Senesces at 38 PDL (PubMed=17395773)., Characteristics: Used in many context such as senescence and aging studies., Biotechnology: Was used in the early 1970's for the production of the Human Diploid Cell Vaccine (HDCV) vaccine against rabies by Institut Merieux., Biotechnology: Used for the production of live oral adenovirus type 4 and type 7 vaccine used by the US military. Produced first by Wyeth Laboratories from 1971 to 1999 and from 2011 onward by Barr Pharmaceuticals., Biotechnology: Used for the production of RA27/3 - the first rubella virus vaccine., Population: Caucasian; Swedish., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut).
Category: Finite cell line
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No rating or validation information has been found for WI-38.
Discontinued
Discontinued: ATCC; CRL-7728
Discontinued
Discontinued: JCRB; JCRB9017
Possibly Discontinued
Discontinued: KCLB; 10075
Source: Cellosaurus (RRID:SCR_013869)
Description: Database of all cell lines used in biomedical research which include immortalized cell lines, naturally immortal cell lines (stem cells), widely used and distributed finite life cell lines, vertebrate cell lines (majority being human, mouse, and rat), and invertebrate (insects and ticks) cell lines, as well as cell line synonyms. Each cell line is provided with the following information: the recommended name (the name which appears in the original publication), a list of synonyms, a unique accession number, comments on a number of topics including misspellings and gene transfection, information on the tissue/organ origin with the UBERON code, the NCI Thesaurus or Orphanet ORDO code for the disease(s) the individual suffered from (for cancer and human genetic disease lines only), the species of origin, the parent cell line, cross-references of sister cell lines, the sex of the individual, the category in which the cell line belongs (Adult stem cell; Cancer cell line; Embryonic stem cell; Factor-dependent cell line; Finite cell line; Hybrid cell line; Hybridoma; Induced pluripotent stem cell; Spontaneously immortalized cell line; Stromal cell line; Telomerase immortalized cell line; Transformed cell line; Undefined cell line type), web links, publication references, and/or cross-references to cell line catalogs/collections, ontologies, cell lines databases/resources, and to databases that list cell lines as samples.
URL: https://www.cellosaurus.org/
