URL: http://antibodyregistry.org/AB_357344
Proper Citation: (R and D Systems Cat# MAB002, RRID:AB_357344)
Target Antigen: Mouse IgG1 Isotype Control (Clone 11711)
Host Organism: mouse
Clonality: unknown
Comments: vendor recommendations: Other; Control
Expand AllWe found {{ ctrl2.mentions.total_count }} mentions in open access literature.
We have not found any literature mentions for this resource.
We are searching literature mentions for this resource.
Most recent articles:
{{ mention._source.dc.creators[0].familyName }} {{ mention._source.dc.creators[0].initials }}, et al. ({{ mention._source.dc.publicationYear }}) {{ mention._source.dc.title }} {{ mention._source.dc.publishers[0].name }}, {{ mention._source.dc.publishers[0].volume }}({{ mention._source.dc.publishers[0].issue }}), {{ mention._source.dc.publishers[0].pagination }}. (PMID:{{ mention._id.replace('PMID:', '') }})
Check
for all resource mentions.
A list of researchers who have used the resource and an author search tool
Find mentions based on location
{{ ctrl2.mentions.errors.location }}
A list of researchers who have used the resource and an author search tool. This is available for resources that have literature mentions.
No rating or validation information has been found for Mouse IgG1 Isotype Control (Clone 11711).
Possibly Non-Specific
Extracted Antibody Information: "Human Na V1.7 stably transfected HEK293 cells, human Na V1.7 stably transfected, inducible CHO-K1 cells, human Na V1.7 BacMam transduced U-2 OS and parental cells were treated with non-enzymatic dissociation buffer (Sigma-Aldrich, #C5914) to remove cells from the flask prior to FACS assays. In 96-well V-bottom plates (Costar, #3897), 50,000 cells/well were incubated with 33nM rSVmab1 or isotype control (R&D Systems, #MAB002; RRID: AB_357344;"
Extracted Specificity Statement: "At the concentrations tested, recombinant monoclonal antibody SVmab1, generated from published sequence information 8, did not bind to the following target sources: Na V1.7 peptide VELFLADVEG, Na V1.7 DII voltage sensor protein, and Na V1.7 expressing mammalian cells (HEK293, CHO-K1, U-2 OS). Recombinant SVmab1 also did not specifically block Na V1.7 currents in HEK293 cells, as assessed by whole cell manual patch clamp electrophysiology when channels were closed/resting, inactivated, or cycled through states to expose the voltage sensor paddle region using a train of depolarizing stimuli. Reductions in Na V1.7 current were comparable when using an isotype control IgG1 or recombinant SVmab1 at 500nM."
Data was mined by Antibody Watch (https://arxiv.org/pdf/2008.01937.pdf), from PMID:27990272
Source: Antibody Registry
