URL: http://antibodyregistry.org/AB_2756529
Proper Citation: (Anne White, University of Manchester, UK Cat# A1A12, RRID:AB_2756529)
Target Antigen: ACTH
Host Organism: mouse
Clonality: monoclonal
Comments: (White et al (1985). Characterisation of monoclonal antibodies to adrenocorticotrophin. J. Immunological Methods 79 (2) 185-194: "We have produced 8 monoclonal antibodies to adrenocorticotrophin (ACTH) derived from immunisation with ACTH (1-24) conjugated to bovine serum albumin or ACTH (1-39) linked to chicken immunoglobulin by a novel method. Antibody specificity was assessed by studying the binding of purified human ACTH, synthetic ACTH (1-24), fragments of ACTH and peptides from the ACTH precursor molecule which have sequence homology. A wide range of specificities was demonstrated. Thus antibody 3H9 recognises the extreme N-terminal sequence (ACTH 4-10), antibody 1A12 is specific for residues 10-18 including alpha MSH, antibody 1D1 is specific for the mid N-terminal sequence but not alpha MSH, and antibody 2A3 is specific for the C-terminal portion (ACTH 18-39)."
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Source: Antibody Registry
