URL: http://antibodyregistry.org/AB_2619682
Proper Citation: Dr. Muhlenhoff Medizinische Hochschule Hannover Cat# mab-735, RRID:AB_2619682
Target Antigen: Polysialic acid
Host Organism: mouse
Clonality: monoclonal
Comments: Recognizes Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), which shares molecular epitopes with homopolymers of a2,8-linked sialic acid ofEscherichia coli K1. This antibody recognises an unusual postranslational modification on neural cell adhesion molecules important in synaptogenesis, oncogenesis (particularly small-cell lung cancer) and development of organs such as the kidney (studied in rats, Lackie et al. 1990). In addition to various studies on human cells, the antibody, has also been used the study the fine-composition of poly-sialic acid composition in mice (Galuska et al. 2006).
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Source: Antibody Registry
