URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=19165133
Proper Citation: RRID:RGD_19165133
Description: Rattus norvegicus with name F344;SD-C3em1Linf from RGD.
Species: Rattus norvegicus
Notes: This mutant strain was created by CRISPR/Cas9 genome editing system. The mutant carried insertion of a premature termination codon in exon 2 and was predicted to result in loss of protein expression due to non-sense mediated decay of mRNA. The heterozygous knock out rats (F344/Sprague Dawley mixed background) were bred to each other, and the pups were genotyped to identify the WT and C3 homozygous knock out littermates.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)