Intranasal SARS-CoV-2 Omicron variant vaccines elicit humoral and cellular mucosal immunity in female mice.
In order to prevent the emergence and spread of future variants of concern of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), developing vaccines capable of stopping transmission is crucial. The SARS-CoV-2 vaccine NDV-HXP-S can be administered live intranasally (IN) and thus induce protective immunity in the upper respiratory tract. The vaccine is based on Newcastle disease virus (NDV) expressing a stabilised SARS-CoV-2 spike protein. NDV-HXP-S can be produced as influenza virus vaccine at low cost in embryonated chicken eggs.
Pubmed ID: 38848648 RIS Download
Additional research tools detected in this publication
Antibodies used in this publication
- Pacific Blue(TM) anti-mouse CD4 (RRID:AB_493647)
- PE/Cyanine7 anti-mouse CD38 (RRID:AB_2275531)
- PerCP/Cyanine5.5 anti-MU/HU GL7 Antigen (T/B Cell Act. Marker) (RRID:AB_2562979)
- APC/Cyanine7 anti-mouse IgM (RRID:AB_10660305)
- Brilliant Violet 605(TM) anti-mouse IgD (RRID:AB_2562887)
- Brilliant Violet 785(TM) anti-mouse CD19 (RRID:AB_11218994)
- Alexa Fluor(R) 700 anti-mouse/human CD45R/B220 (RRID:AB_493717)
- Pacific Blue(TM) anti-mouse CD3 (RRID:AB_493645)
- IL-17A (RRID:AB_2738641)
- APC anti-mouse IL-4 (RRID:AB_315320)
- PE/Cyanine7 anti-mouse IL-2 (RRID:AB_2561750)
- PerCP/Cyanine5.5 anti-mouse CD8a (RRID:AB_2075238)
- Alexa Fluor(R) 488 anti-mouse TNF-alpha (RRID:AB_493328)
- Alexa Fluor(R) 647 anti-mouse IFN-gamma (RRID:AB_493314)
- CD154 (CD40 Ligand) Monoclonal Antibody (MR1), PE, eBioscience (RRID:AB_465887)
- Ms CD44 BUV737 IM7 50ug (RRID:AB_2870126)
- MHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), eFluor™ 450, eBioscience (RRID:AB_1272204)
- Alexa Fluor(R) 700 anti-mouse CD3 (RRID:AB_493696)
- Brilliant Violet 711(TM) anti-mouse CD3 (RRID:AB_2563945)
- MHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), Alexa Fluor™ 700, eBioscience (RRID:AB_494009)
- Syrian Hamster Anti-CD28 Monoclonal Antibody, Unconjugated, Clone 37.51 (RRID:AB_394764)
- APC/Cyanine7 anti-mouse I-A/I-E (RRID:AB_1659252)
- CD19 Monoclonal Antibody (eBio1D3 (1D3)), Alexa Fluor™ 700, eBioscience (RRID:AB_837083)
- Rat Anti-CD8a Monoclonal Antibody, PerCP Conjugated, Clone 53-6.7 (RRID:AB_394573)
- CD44 (RRID:AB_11153123)
- IgA Monoclonal Antibody (mA-6E1), PE, eBioscience (RRID:AB_465917)
- CD103 (Integrin alpha E) Monoclonal Antibody (2E7), APC, eBioscience (RRID:AB_1106992)
- Armenian Hamster Anti-CD3e Monoclonal Antibody, FITC Conjugated, Clone 145-2C11 (RRID:AB_394595)
- Purified Rat Anti-Mouse CD16/CD32 (Mouse BD Fc Block™) Clone 2.4G2 (RRID:AB_394656)
- Brilliant Violet 421-conjugated anti-CD45 (RRID:AB_2651151)
- Goat anti-Mouse IgA Antibody HRP Conjugated (RRID:AB_67140)
- Armenian Hamster Anti-CD69 Monoclonal Antibody, PE-Cy7 Conjugated, Clone H1.2F3 (RRID:AB_394508)
- Sheep Anti-Mouse IgG - Horseradish Peroxidase (RRID:AB_772210)
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This is a list of tools and resources that we have found mentioned in this publication.
ATCC (tool)
RRID:SCR_001672
Global nonprofit biological resource center (BRC) and research organization that provides biological products, technical services and educational programs to private industry, government and academic organizations. Its mission is to acquire, authenticate, preserve, develop and distribute biological materials, information, technology, intellectual property and standards for the advancement and application of scientific knowledge. The primary purpose of ATCC is to use its resources and experience as a BRC to become the world leader in standard biological reference materials management, intellectual property resource management and translational research as applied to biomaterial development, standardization and certification. ATCC characterizes cell lines, bacteria, viruses, fungi and protozoa, as well as develops and evaluates assays and techniques for validating research resources and preserving and distributing biological materials to the public and private sector research communities.
View all literature mentionsFlowJo (tool)
RRID:SCR_008520
Software for single-cell flow cytometry analysis. Its functions include management, display, manipulation, analysis and publication of the data stream produced by flow and mass cytometers.
View all literature mentionsBiorender (tool)
RRID:SCR_018361
Web tool for graphical illustrations for biological systems by BioRender. Used for articles and presentations. Collection of pre made icons and templates from life science fields for scientific illustrations. Customized icons possible on request.
View all literature mentionsBALB/cAnNCrl (tool)
RRID:MGI:2683685
laboratory mouse with name BALB/cAnNCrl from MGI.
View all literature mentionsPacific Blue(TM) anti-mouse CD4 (antibody)
RRID:AB_493647
This monoclonal targets CD4
View all literature mentionsPE/Cyanine7 anti-mouse CD38 (antibody)
RRID:AB_2275531
This monoclonal targets CD38
View all literature mentionsPerCP/Cyanine5.5 anti-MU/HU GL7 Antigen (T/B Cell Act. Marker) (antibody)
RRID:AB_2562979
This monoclonal targets GL7
View all literature mentionsAPC/Cyanine7 anti-mouse IgM (antibody)
RRID:AB_10660305
This monoclonal targets IgM
View all literature mentionsBrilliant Violet 605(TM) anti-mouse IgD (antibody)
RRID:AB_2562887
This monoclonal targets IgD
View all literature mentionsBrilliant Violet 785(TM) anti-mouse CD19 (antibody)
RRID:AB_11218994
This monoclonal targets CD19
View all literature mentionsAlexa Fluor(R) 700 anti-mouse/human CD45R/B220 (antibody)
RRID:AB_493717
This monoclonal targets CD45R
View all literature mentionsPacific Blue(TM) anti-mouse CD3 (antibody)
RRID:AB_493645
This monoclonal targets CD3
View all literature mentionsAPC anti-mouse IL-4 (antibody)
RRID:AB_315320
This monoclonal targets IL-4
View all literature mentionsPE/Cyanine7 anti-mouse IL-2 (antibody)
RRID:AB_2561750
This monoclonal targets IL-2
View all literature mentionsPerCP/Cyanine5.5 anti-mouse CD8a (antibody)
RRID:AB_2075238
This monoclonal targets CD8a
View all literature mentionsAlexa Fluor(R) 488 anti-mouse TNF-alpha (antibody)
RRID:AB_493328
This monoclonal targets TNF-alpha
View all literature mentionsAlexa Fluor(R) 647 anti-mouse IFN-gamma (antibody)
RRID:AB_493314
This monoclonal targets IFN-gamma
View all literature mentionsCD154 (CD40 Ligand) Monoclonal Antibody (MR1), PE, eBioscience (antibody)
RRID:AB_465887
This monoclonal targets CD154 (CD40 Ligand)
View all literature mentionsMs CD44 BUV737 IM7 50ug (antibody)
RRID:AB_2870126
This monoclonal targets CD44
View all literature mentionsMHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), eFluor™ 450, eBioscience (antibody)
RRID:AB_1272204
This monoclonal targets MHC Class II (I-A/I-E)
View all literature mentionsAlexa Fluor(R) 700 anti-mouse CD3 (antibody)
RRID:AB_493696
This monoclonal targets CD3
View all literature mentionsBrilliant Violet 711(TM) anti-mouse CD3 (antibody)
RRID:AB_2563945
This monoclonal targets CD3
View all literature mentionsMHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), Alexa Fluor™ 700, eBioscience (antibody)
RRID:AB_494009
This monoclonal targets MHC Class II (I-A/I-E)
View all literature mentionsSyrian Hamster Anti-CD28 Monoclonal Antibody, Unconjugated, Clone 37.51 (antibody)
RRID:AB_394764
This monoclonal targets CD28
View all literature mentionsAPC/Cyanine7 anti-mouse I-A/I-E (antibody)
RRID:AB_1659252
This monoclonal targets I-A/I-E
View all literature mentionsCD19 Monoclonal Antibody (eBio1D3 (1D3)), Alexa Fluor™ 700, eBioscience (antibody)
RRID:AB_837083
This monoclonal targets CD19
View all literature mentionsRat Anti-CD8a Monoclonal Antibody, PerCP Conjugated, Clone 53-6.7 (antibody)
RRID:AB_394573
This monoclonal targets CD8a
View all literature mentionsIgA Monoclonal Antibody (mA-6E1), PE, eBioscience (antibody)
RRID:AB_465917
This monoclonal targets IgA
View all literature mentionsCD103 (Integrin alpha E) Monoclonal Antibody (2E7), APC, eBioscience (antibody)
RRID:AB_1106992
This monoclonal targets CD103 (Integrin alpha E)
View all literature mentionsArmenian Hamster Anti-CD3e Monoclonal Antibody, FITC Conjugated, Clone 145-2C11 (antibody)
RRID:AB_394595
This monoclonal targets CD3e
View all literature mentionsPurified Rat Anti-Mouse CD16/CD32 (Mouse BD Fc Block™) Clone 2.4G2 (antibody)
RRID:AB_394656
This monoclonal targets CD16/CD32
View all literature mentionsBrilliant Violet 421-conjugated anti-CD45 (antibody)
RRID:AB_2651151
This monoclonal targets CD-45
View all literature mentionsGoat anti-Mouse IgA Antibody HRP Conjugated (antibody)
RRID:AB_67140
This polyclonal targets IgA
View all literature mentionsArmenian Hamster Anti-CD69 Monoclonal Antibody, PE-Cy7 Conjugated, Clone H1.2F3 (antibody)
RRID:AB_394508
This monoclonal targets CD69
View all literature mentionsSheep Anti-Mouse IgG - Horseradish Peroxidase (antibody)
RRID:AB_772210
This monoclonal secondary targets IgG
View all literature mentionsB6.Cg-Tg(K18-ACE2)2Prlmn/J (organism)
RRID:IMSR_JAX:034860
Mus musculus with name B6.Cg-Tg(K18-ACE2)2Prlmn/J from IMSR.
View all literature mentionsBALB/cJ (organism)
RRID:IMSR_JAX:000651
Mus musculus with name BALB/cJ from IMSR.
View all literature mentionsVero E6-TMPRSS2-T2A-ACE2 (cell line)
RRID:CVCL_C7NK
Cell line Vero E6-TMPRSS2-T2A-ACE2 is a Spontaneously immortalized cell line with a species of origin Chlorocebus sabaeus (Green monkey)
View all literature mentionsUMNSAH/DF-1 (cell line)
RRID:CVCL_0570
Cell line UMNSAH/DF-1 is a Spontaneously immortalized cell line with a species of origin Gallus gallus
View all literature mentions
