Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer.
Risk of recurrence and progression of ductal carcinoma in situ (DCIS) to invasive cancer remains uncertain, emphasizing the need for developing predictive biomarkers of aggressive DCIS.
Pubmed ID: 38760444 RIS Download
Research resources used in this publication
- T-47D (RRID: CVCL_0553) (cell line)
- BT-474 (RRID: CVCL_0179) (cell line)
- 21NT (RRID: CVCL_7933) (cell line)
- SUM149PT (RRID:CVCL_3422) (cell line)
- 21MT-1 (RRID: CVCL_7931) (cell line)
- MDA-MB-231 (RRID: CVCL_0062) (cell line)
- MDA-MB-468 (RRID: CVCL_0419) (cell line)
- STOCK Tg(MMTV-cre)4Mam/J (RRID:IMSR_JAX:003553) (organism)
- FVB/N-Tg(MMTVneu)202Mul/J (RRID:IMSR_JAX:002376) (organism)
- GraphPad Prism (RRID:SCR_002798) (software resource)
- JARID1B (E2X6N) Rabbit mAb (RRID:AB_2798737) (antibody)
- Rabbit Anti-JARID1A Monoclonal Antibody, Unconjugated, Clone D28B10 (RRID:AB_2129055) (antibody)
- MDA-MB-453 (RRID:CVCL_0418) (cell line)
- FVB.129S4(Cg)-Ptentm1Hwu/JwkimJ (RRID:IMSR_JAX:034621) (organism)
- SUM159PT (RRID:CVCL_5423) (cell line)
- SK-BR-3 (RRID:CVCL_0033) (cell line)
- ZR-75-1 (RRID:CVCL_0588) (cell line)
- MCF-7 (RRID:CVCL_0031) (cell line)
- SUM225CWN (RRID:CVCL_5593) (cell line)
- MCF10DCIS.com (RRID:CVCL_5552) (cell line)
- 21MT-1 (RRID:CVCL_7931) (cell line)
- 21PT (RRID:CVCL_7934) (cell line)
- MCF-10A (RRID:CVCL_0598) (cell line)
- STAR (RRID:SCR_004463) (software resource)
- Trim Galore (RRID:SCR_011847) (data processing software)
- DESeq (RRID:SCR_000154) (software resource)
- Subread (RRID:SCR_009803) (data processing software)
Additional research tools detected in this publication
None foundAntibodies used in this publication
- HER2/ErbB2 (29D8) Rabbit mAb (RRID:AB_10692490)
- Rabbit Anti-JARID1A Monoclonal Antibody, Unconjugated, Clone D28B10 (RRID:AB_2129055)
- JARID1B (E2X6N) Rabbit mAb (RRID:AB_2798737)
- HER2/ErbB2 (D8F12) XP Rabbit mAb (RRID:AB_10557104)
- PARP (46D11) Rabbit mAb (RRID:AB_659884)
- Histone H3 (D1H2) XP Rabbit mAb (RRID:AB_10544537)
- H3K27ac-human (RRID:AB_10949503)
- H3K4me3-human (RRID:AB_2616028)
- Phospho-HER2/ErbB2 (Tyr877) Antibody (RRID:AB_2099407)
- Akt Antibody (RRID:AB_329827)
- Phospho-Akt (Ser473) (D9E) XP® Rabbit mAb (RRID:AB_2315049)
- PTEN (D4.3) XP Rabbit mAb (RRID:AB_2253290)
- Anti-SOX11 antibody produced in rabbit (RRID:AB_1080060)
- Normal Rabbit IgG (RRID:AB_1031062)
- β-Actin (8H10D10) Mouse mAb (RRID:AB_2242334)
- EZH2-human (RRID:AB_10694683)
- VENTANA anti-HER2/neu (4B5) Rabbit Monoclonal Primary Antibody (RRID:AB_2921204)
- HIV-1 p24 Monoclonal Antibody (RRID:AB_2334781)
- SOX-11 (MRQ-58) Mouse Monoclonal Antibody (RRID:AB_3073904)
Associated grants
- Agency: NCI NIH HHS, United States
Id: T32 CA217789 - Agency: Breast Cancer Now, United Kingdom
Id: TAP379 - Agency: Cancer Research UK (CRUK),
Id: C38317/A24043
Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.
This is a list of tools and resources that we have found mentioned in this publication.
HER2/ErbB2 (29D8) Rabbit mAb (antibody)
RRID:AB_10692490
This monoclonal targets HER2/ErbB2 (29D8) Rabbit mAb
View all literature mentionsRabbit Anti-JARID1A Monoclonal Antibody, Unconjugated, Clone D28B10 (antibody)
RRID:AB_2129055
This monoclonal targets JARID1A
View all literature mentionsJARID1B (E2X6N) Rabbit mAb (antibody)
RRID:AB_2798737
This monoclonal targets JARID1B
View all literature mentionsHER2/ErbB2 (D8F12) XP Rabbit mAb (antibody)
RRID:AB_10557104
This monoclonal targets HER2/ErbB2 (D8F12) XP Rabbit mAb
View all literature mentionsPARP (46D11) Rabbit mAb (antibody)
RRID:AB_659884
This monoclonal targets PARP
View all literature mentionsHistone H3 (D1H2) XP Rabbit mAb (antibody)
RRID:AB_10544537
This monoclonal targets Histone H3 (D1H2) XP Rabbit mAb
View all literature mentionsH3K4me3-human (antibody)
RRID:AB_2616028
This monoclonal targets H3K4me3
View all literature mentionsPhospho-HER2/ErbB2 (Tyr877) Antibody (antibody)
RRID:AB_2099407
This polyclonal targets Erbb2
View all literature mentionsPhospho-Akt (Ser473) (D9E) XP® Rabbit mAb (antibody)
RRID:AB_2315049
This monoclonal targets Phospho-Akt (Ser473)
View all literature mentionsPTEN (D4.3) XP Rabbit mAb (antibody)
RRID:AB_2253290
This monoclonal targets PTEN (D4.3) XP Rabbit mAb
View all literature mentionsAnti-SOX11 antibody produced in rabbit (antibody)
RRID:AB_1080060
This monoclonal targets ND
View all literature mentionsNormal Rabbit IgG (antibody)
RRID:AB_1031062
This isotype control targets not applicable
View all literature mentionsβ-Actin (8H10D10) Mouse mAb (antibody)
RRID:AB_2242334
This monoclonal targets beta-actin
View all literature mentionsVENTANA anti-HER2/neu (4B5) Rabbit Monoclonal Primary Antibody (antibody)
RRID:AB_2921204
This monoclonal targets HER2
View all literature mentionsHIV-1 p24 Monoclonal Antibody (antibody)
RRID:AB_2334781
This unknown targets HIV-1 p24
View all literature mentionsSOX-11 (MRQ-58) Mouse Monoclonal Antibody (antibody)
RRID:AB_3073904
This monoclonal targets SOX-11
View all literature mentionsT-47D (cell line)
RRID: CVCL_0553
Cell line T-47D is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsBT-474 (cell line)
RRID: CVCL_0179
Cell line BT-474 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentions21NT (cell line)
RRID: CVCL_7933
Cell line 21NT is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsSUM149PT (cell line)
RRID:CVCL_3422
Cell line SUM149PT is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentions21MT-1 (cell line)
RRID: CVCL_7931
Cell line 21MT-1 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsMDA-MB-231 (cell line)
RRID: CVCL_0062
Cell line MDA-MB-231 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsMDA-MB-468 (cell line)
RRID: CVCL_0419
Cell line MDA-MB-468 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsSTOCK Tg(MMTV-cre)4Mam/J (organism)
RRID:IMSR_JAX:003553
Mus musculus with name STOCK Tg(MMTV-cre)4Mam/J from IMSR.
View all literature mentionsFVB/N-Tg(MMTVneu)202Mul/J (organism)
RRID:IMSR_JAX:002376
Mus musculus with name FVB/N-Tg(MMTVneu)202Mul/J from IMSR.
View all literature mentionsGraphPad Prism (software resource)
RRID:SCR_002798
Statistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.
View all literature mentionsJARID1B (E2X6N) Rabbit mAb (antibody)
RRID:AB_2798737
This monoclonal targets JARID1B
View all literature mentionsRabbit Anti-JARID1A Monoclonal Antibody, Unconjugated, Clone D28B10 (antibody)
RRID:AB_2129055
This monoclonal targets JARID1A
View all literature mentionsMDA-MB-453 (cell line)
RRID:CVCL_0418
Cell line MDA-MB-453 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsFVB.129S4(Cg)-Ptentm1Hwu/JwkimJ (organism)
RRID:IMSR_JAX:034621
Mus musculus with name FVB.129S4(Cg)-Ptentm1Hwu/JwkimJ from IMSR.
View all literature mentionsSUM159PT (cell line)
RRID:CVCL_5423
Cell line SUM159PT is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsSK-BR-3 (cell line)
RRID:CVCL_0033
Cell line SK-BR-3 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsZR-75-1 (cell line)
RRID:CVCL_0588
Cell line ZR-75-1 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsMCF-7 (cell line)
RRID:CVCL_0031
Cell line MCF-7 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsSUM225CWN (cell line)
RRID:CVCL_5593
Cell line SUM225CWN is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsMCF10DCIS.com (cell line)
RRID:CVCL_5552
Cell line MCF10DCIS.com is a Transformed cell line with a species of origin Homo sapiens (Human)
View all literature mentions21MT-1 (cell line)
RRID:CVCL_7931
Cell line 21MT-1 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentions21PT (cell line)
RRID:CVCL_7934
Cell line 21PT is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsMCF-10A (cell line)
RRID:CVCL_0598
Cell line MCF-10A is a Spontaneously immortalized cell line with a species of origin Homo sapiens
View all literature mentionsSTAR (software resource)
RRID:SCR_004463
Software performing alignment of high-throughput RNA-seq data. Aligns RNA-seq reads to reference genome using uncompressed suffix arrays.
View all literature mentionsTrim Galore (data processing software)
RRID:SCR_011847
Software tool to automate quality and adapter trimming as well as quality control, with some added functionality to remove biased methylation positions for RRBS sequence files for directional, non-directional or paired-end sequencing. Wrapper around Cutadapt and FastQC to consistently apply adapter and quality trimming to FastQ files, with extra functionality for Reduced Representation Bisulfite Sequencing data.
View all literature mentionsDESeq (software resource)
RRID:SCR_000154
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Software for differential gene expression analysis based on the negative binomial distribution. It estimates variance-mean dependence in count data from high-throughput sequencing assays and tests for differential expression.
View all literature mentionsSubread (data processing software)
RRID:SCR_009803
Software package for high-performance read alignment, quantification and mutation discovery.General purpose read aligner which can be used to map both genomic DNA-seq reads and RNA-seq reads. Subread aligner as fast, accurate and scalable read mapping by seed-and-vote.These programs were also implemented in Bioconductor R package Rsubread.
View all literature mentions
