Complex formation of immunoglobulin superfamily molecules Side-IV and Beat-IIb regulates synaptic specificity.
Neurons establish specific synapses based on the adhesive properties of cell-surface proteins while also retaining the ability to form synapses in a relatively non-selective manner. However, comprehensive understanding of the underlying mechanism reconciling these opposing characteristics remains incomplete. Here, we have identified Side-IV/Beat-IIb, members of the Drosophila immunoglobulin superfamily, as a combination of cell-surface recognition molecules inducing synapse formation. The Side-IV/Beat-IIb combination transduces bifurcated signaling with Side-IV's co-receptor, Kirre, and a synaptic scaffold protein, Dsyd-1. Genetic experiments and subcellular protein localization analyses showed the Side-IV/Beat-IIb/Kirre/Dsyd-1 complex to have two essential functions. First, it narrows neuronal binding specificity through Side-IV/Beat-IIb extracellular interactions. Second, it recruits synapse formation factors, Kirre and Dsyd-1, to restrict synaptic loci and inhibit miswiring. This dual function explains how the combinations of cell-surface molecules enable the ranking of preferred interactions among neuronal pairs to achieve synaptic specificity in complex circuits in vivo.
Pubmed ID: 38381608 RIS Download
Research resources used in this publication
- y[1] v[1]; P{y[+t7.7] v[+t1.8]=WKO.5-C1}attP40 (RRID:BDSC_84159) (organism)
- y[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=TKO.GS04527}attP40 (RRID:BDSC_82064) (organism)
- y[1] M{RFP[3xP3.PB] GFP[E.3xP3]=vas-int.Dm}ZH-2A w[*]; PBac{y[+]-attP-3B}VK00033 (RRID:BDSC_24871) (organism)
- y[1] M{RFP[3xP3.PB] GFP[E.3xP3]=vas-int.Dm}ZH-2A w[*]; PBac{y[+]-attP-3B}VK00037 (RRID:BDSC_24872) (organism)
- y[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=nos-Cas9.R}attP2 (RRID:BDSC_78782) (organism)
- y[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=nos-Cas9.R}attP40 (RRID:BDSC_78781) (organism)
- y[1] w[*]; Mi{PT-GFSTF.1}beat-IV[MI05715-GFSTF.1]/TM3, Sb[1] Ser[1] (RRID:BDSC_66506) (organism)
- y[1] w[*]; Mi{PT-GFSTF.0}beat-IIb[MI03102-GFSTF.0] (RRID:BDSC_59406) (organism)
- pr[1] pwn[1] P{ry[+t7.2]=hsFLP}38/CyO; Ki[1] kar[1] ry[506] (RRID:BDSC_5258) (organism)
- w[*]; P{y[+t7.7] w[+mC]=R27G05-FLPG5.PEST}attP40/CyO, P{w[+mC]=GAL4-Kr.C}DC3, P{w[+mC]=UAS-GFP.S65T}DC7; TM2/TM6B, Tb[1] (RRID:BDSC_55765) (organism)
- w[*]; P{y[+t7.7] w[+mC]=20C11-FLPG5}attP40/CyO; TM2/TM6B, Tb[1] (RRID:BDSC_55766) (organism)
- w[*]; P{y[+t7.7] w[+mC]=LexAop-tdTomato.Myr}su(Hw)attP5 PBac{y[+mDint2] w[+mC]=brp(FRT.Stop)V5-2A-LexA-VP16}VK00018/CyO; TM2/TM6B, Tb[1] (RRID:BDSC_56142) (organism)
- w[*]; Bl[1]/CyO, P{w[+mC]=GAL4-Kr.C}DC3, P{w[+mC]=UAS-GFP.S65T}DC7; PBac{y[+mDint2] w[+mC]=brp(FRT.Stop)GFP}VK00033 (RRID:BDSC_55753) (organism)
- w[1118] P{y[+t7.7] w[+mC]=hs-FLPG5.PEST}attP3; P{y[+t7.7] w[+mC]=10xUAS(FRT.stop)myr::smGdP-OLLAS}attP2 PBac{y[+mDint2] w[+mC]=10xUAS(FRT.stop)myr::smGdP-HA}VK00005 P{10xUAS(FRT.stop)myr::smGdP-V5-THS-10xUAS(FRT.stop)myr::smGdP-FLAG}su(Hw)attP1 (RRID:BDSC_64086) (organism)
- w[*]; P{w[+mC]=UAS-MYC-Liprin-alpha.H}2/CyO (RRID:BDSC_63809) (organism)
- y[1] w[1118]; P{w[+mC]=UAS-kirre.C-HA}2/CyO (RRID:BDSC_92196) (organism)
- P{w[+mC]=UAS-side.S}46, w[*] (RRID:BDSC_9679) (organism)
- w[1118]; P{w[+mC]=EP}side-VIII[EP2424] (RRID:BDSC_17248) (organism)
- y[1] v[1]; P{y[+t7.7] v[+t1.8]=TRiP.HMC03183}attP40 (RRID:BDSC_53868) (organism)
- y[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=TRiP.HMS00740}attP2 (RRID:BDSC_32946) (organism)
- w[1118]; P{GD14476}v27227 (RRID:Flybase_FBst0456824) (organism)
- P{KK106353}VIE-260B (RRID:Flybase_FBst0472832) (organism)
- w[1118]; P{GD2175}v44997/TM3 (RRID:Flybase_FBst0465867) (organism)
- w[1118]; P{GD5643}v16636 (RRID:Flybase_FBst0452368) (organism)
- w[1118]; P{GD12854}v22742 (RRID:Flybase_FBst0454672) (organism)
- P{KK101967}VIE-260B (RRID:Flybase_FBst0482037) (organism)
- w[1118]; P{GD321}v1283 (RRID:Flybase_FBst0450699) (organism)
- P{KK106470}VIE-260B (RRID:Flybase_FBst0481835) (organism)
- w[1118]; P{GD6812}v27137 (RRID:Flybase_FBst0456776) (organism)
- P{KK104935}VIE-260B (RRID:Flybase_FBst0479711) (organism)
- y[1] v[1]; P{y[+t7.7] v[+t1.8]=TRiP.JF02909}attP2 (RRID:BDSC_28072) (organism)
- y[1] v[1]; P{y[+t7.7] v[+t1.8]=UAS-LUC.VALIUM10}attP2 (RRID:BDSC_35788) (organism)
- w[1118]; P{w[+mC]=UAS-myr-mRFP}1 (RRID:BDSC_7118) (organism)
- w[1118]; P{w[+mC]=UAS-myr-mRFP}2/TM6B, Tb[1] (RRID:BDSC_7119) (organism)
- w[*]; P{y[+t7.7] w[+mC]=10XUAS-IVS-mCD8::GFP}attP40 (RRID:BDSC_32186) (organism)
- y[1] w[*]; P{w[+mC]=UAS-FLP.D}JD1 (RRID:BDSC_4539) (organism)
- P{w[+mC]=UAS-FLP.Exel}1, y[1] w[1118] (RRID:BDSC_8208) (organism)
- w[1118]; P{y[+t7.7] w[+mC]=R37E10-GAL4.DBD}attP2 (RRID:BDSC_69000) (organism)
- w[1118]; P{y[+t7.7] w[+mC]=R64B07-p65.AD}attP40 (RRID:BDSC_71106) (organism)
- w[1118]; P{y[+t7.7] w[+mC]=GMR31C06-GAL4}attP2 (RRID:BDSC_49883) (organism)
- w[1118]; P{y[+t7.7] w[+mC]=R34G07-GAL4.DBD}attP2 (RRID:BDSC_69029) (organism)
- w[1118]; P{y[+t7.7] w[+mC]=R31C06-p65.AD}attP40; MKRS/TM6B, Tb[1] (RRID:BDSC_70646) (organism)
- w[1118]; P{y[+t7.7] w[+mC]=R14B07-GAL4.DBD}attP2 (RRID:BDSC_68940) (organism)
- w[1118]; P{y[+t7.7] w[+mC]=R64B03-p65.AD}attP40; P{y[+t7.7] w[+mC]=R29G08-GAL4.DBD}attP2 (RRID:BDSC_75895) (organism)
- w[1118]; P{y[+t7.7] w[+mC]=GMR16H03-GAL4}attP2 (RRID:BDSC_48744) (organism)
- w[1118]; P{y[+t7.7] w[+mC]=R66A01-GAL4.DBD}attP2 (RRID:BDSC_68999) (organism)
- w[1118]; P{y[+t7.7] w[+mC]=R48A08-p65.AD}attP40; MKRS/TM6B, Tb[1] (RRID:BDSC_70707) (organism)
- w[1118]; P{w[+mC]=AyGAL4}17b (RRID:BDSC_4413) (organism)
- w[1118]; P{w[+mC]=AyGAL4}25/CyO (RRID:BDSC_3953) (organism)
- w[*]; P{w[+mC]=longGMR-GAL4}2 (RRID:BDSC_8605) (organism)
- GH14967 (RRID:DGRC_4843) (plasmid)
- RE17755 (RRID:DGRC_1090247) (plasmid)
- RE17794 (RRID:DGRC_8501) (plasmid)
Additional research tools detected in this publication
None foundAntibodies used in this publication
- Goat anti-Mouse IgG (H+L) Secondary Antibody, HRP (RRID:AB_1185566)
- Goat Anti-Rat IgG (H+L) Antibody, Alexa Fluor ?? 568 Conjugated (RRID:AB_141874)
- Goat Anti-Rat IgG (H+L) Antibody, Alexa Fluor ?? 488 Conjugated (RRID:AB_141373)
- Goat Anti-Mouse IgG (H+L) Highly Cross-adsorbed Antibody, Alexa Fluor 633 Conjugated (RRID:AB_2535719)
- Goat Anti-Mouse IgG (H+L) Highly Cross-adsorbed Antibody, Alexa Fluor ?? 568 Conjugated (RRID:AB_144696)
- Goat Anti-Mouse IgG (H+L) Highly Cross-adsorbed Antibody, Alexa Fluor 488 Conjugated (RRID:AB_2534088)
- Anti-α-Tubulin antibody (RRID:AB_477593)
- Rabbit Anti-Green Fluorescent Protein (GFP) Polyclonal Antibody, Unconjugated (RRID:AB_221569)
- Anti-Myc Tag, clone 4A6 (RRID:AB_568800)
- Anti-HA High Affinity; Rat monoclonal antibody (clone 3F10) (RRID:AB_390918)
- V5 Tag Monoclonal Antibody (SV5-Pk1) (RRID:AB_2556564)
- cadherin, DN- (extracellular domain) antibody - Uemura, T.; Kyoto Univ. Graduate Sch.of Biostudies (RRID:AB_528121)
- chaoptin antibody - Benzer, S. / Colley, N.; California Institute of Technology (RRID:AB_528161)
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Goat anti-Mouse IgG (H+L) Secondary Antibody, HRP (antibody)
RRID:AB_1185566
This polyclonal secondary targets IgG (H+L)
View all literature mentionsGoat Anti-Rat IgG (H+L) Antibody, Alexa Fluor ?? 568 Conjugated (antibody)
RRID:AB_141874
This unknown targets Rat IgG (H+L)
View all literature mentionsGoat Anti-Rat IgG (H+L) Antibody, Alexa Fluor ?? 488 Conjugated (antibody)
RRID:AB_141373
This unknown targets Rat IgG (H+L)
View all literature mentionsGoat Anti-Mouse IgG (H+L) Highly Cross-adsorbed Antibody, Alexa Fluor 633 Conjugated (antibody)
RRID:AB_2535719
This polyclonal targets Mouse IgG (H+L)
View all literature mentionsGoat Anti-Mouse IgG (H+L) Highly Cross-adsorbed Antibody, Alexa Fluor ?? 568 Conjugated (antibody)
RRID:AB_144696
This unknown targets Mouse IgG (H+L)
View all literature mentionsGoat Anti-Mouse IgG (H+L) Highly Cross-adsorbed Antibody, Alexa Fluor 488 Conjugated (antibody)
RRID:AB_2534088
This polyclonal secondary targets IgG (H+L)
View all literature mentionsAnti-α-Tubulin antibody (antibody)
RRID:AB_477593
This monoclonal targets α-Tubulin
View all literature mentionsRabbit Anti-Green Fluorescent Protein (GFP) Polyclonal Antibody, Unconjugated (antibody)
RRID:AB_221569
This polyclonal targets GFP
View all literature mentionsAnti-Myc Tag, clone 4A6 (antibody)
RRID:AB_568800
This monoclonal targets Human Myc Tag
View all literature mentionsAnti-HA High Affinity; Rat monoclonal antibody (clone 3F10) (antibody)
RRID:AB_390918
This monoclonal targets HA
View all literature mentionsV5 Tag Monoclonal Antibody (SV5-Pk1) (antibody)
RRID:AB_2556564
This monoclonal targets V5 Tag
View all literature mentionscadherin, DN- (extracellular domain) antibody - Uemura, T.; Kyoto Univ. Graduate Sch.of Biostudies (antibody)
RRID:AB_528121
This monoclonal targets cadherin, DN- (extracellular domain)
View all literature mentionschaoptin antibody - Benzer, S. / Colley, N.; California Institute of Technology (antibody)
RRID:AB_528161
This monoclonal targets chaoptin
View all literature mentionsy[1] v[1]; P{y[+t7.7] v[+t1.8]=WKO.5-C1}attP40 (organism)
RRID:BDSC_84159
Drosophila melanogaster with name y[1] v[1]; P{y[+t7.7] v[+t1.8]=WKO.5-C1}attP40 from BDSC.
View all literature mentionsy[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=TKO.GS04527}attP40 (organism)
RRID:BDSC_82064
Drosophila melanogaster with name y[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=TKO.GS04527}attP40 from BDSC.
View all literature mentionsy[1] M{RFP[3xP3.PB] GFP[E.3xP3]=vas-int.Dm}ZH-2A w[*]; PBac{y[+]-attP-3B}VK00033 (organism)
RRID:BDSC_24871
Drosophila melanogaster with name y[1] M{RFP[3xP3.PB] GFP[E.3xP3]=vas-int.Dm}ZH-2A w[*]; PBac{y[+]-attP-3B}VK00033 from BDSC.
View all literature mentionsy[1] M{RFP[3xP3.PB] GFP[E.3xP3]=vas-int.Dm}ZH-2A w[*]; PBac{y[+]-attP-3B}VK00037 (organism)
RRID:BDSC_24872
Drosophila melanogaster with name y[1] M{RFP[3xP3.PB] GFP[E.3xP3]=vas-int.Dm}ZH-2A w[*]; PBac{y[+]-attP-3B}VK00037 from BDSC.
View all literature mentionsy[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=nos-Cas9.R}attP2 (organism)
RRID:BDSC_78782
Drosophila melanogaster with name y[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=nos-Cas9.R}attP2 from BDSC.
View all literature mentionsy[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=nos-Cas9.R}attP40 (organism)
RRID:BDSC_78781
Drosophila melanogaster with name y[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=nos-Cas9.R}attP40 from BDSC.
View all literature mentionsy[1] w[*]; Mi{PT-GFSTF.1}beat-IV[MI05715-GFSTF.1]/TM3, Sb[1] Ser[1] (organism)
RRID:BDSC_66506
Drosophila melanogaster with name y[1] w[*]; Mi{PT-GFSTF.1}beat-IV[MI05715-GFSTF.1]/TM3, Sb[1] Ser[1] from BDSC.
View all literature mentionsy[1] w[*]; Mi{PT-GFSTF.0}beat-IIb[MI03102-GFSTF.0] (organism)
RRID:BDSC_59406
Drosophila melanogaster with name y[1] w[*]; Mi{PT-GFSTF.0}beat-IIb[MI03102-GFSTF.0] from BDSC.
View all literature mentionspr[1] pwn[1] P{ry[+t7.2]=hsFLP}38/CyO; Ki[1] kar[1] ry[506] (organism)
RRID:BDSC_5258
Drosophila melanogaster with name pr[1] pwn[1] P{ry[+t7.2]=hsFLP}38/CyO; Ki[1] kar[1] ry[506] from BDSC.
View all literature mentionsw[*]; P{y[+t7.7] w[+mC]=R27G05-FLPG5.PEST}attP40/CyO, P{w[+mC]=GAL4-Kr.C}DC3, P{w[+mC]=UAS-GFP.S65T}DC7; TM2/TM6B, Tb[1] (organism)
RRID:BDSC_55765
Drosophila melanogaster with name w[*]; P{y[+t7.7] w[+mC]=R27G05-FLPG5.PEST}attP40/CyO, P{w[+mC]=GAL4-Kr.C}DC3, P{w[+mC]=UAS-GFP.S65T}DC7; TM2/TM6B, Tb[1] from BDSC.
View all literature mentionsw[*]; P{y[+t7.7] w[+mC]=20C11-FLPG5}attP40/CyO; TM2/TM6B, Tb[1] (organism)
RRID:BDSC_55766
Drosophila melanogaster with name w[*]; P{y[+t7.7] w[+mC]=20C11-FLPG5}attP40/CyO; TM2/TM6B, Tb[1] from BDSC.
View all literature mentionsw[*]; P{y[+t7.7] w[+mC]=LexAop-tdTomato.Myr}su(Hw)attP5 PBac{y[+mDint2] w[+mC]=brp(FRT.Stop)V5-2A-LexA-VP16}VK00018/CyO; TM2/TM6B, Tb[1] (organism)
RRID:BDSC_56142
Drosophila melanogaster with name w[*]; P{y[+t7.7] w[+mC]=LexAop-tdTomato.Myr}su(Hw)attP5 PBac{y[+mDint2] w[+mC]=brp(FRT.Stop)V5-2A-LexA-VP16}VK00018/CyO; TM2/TM6B, Tb[1] from BDSC.
View all literature mentionsw[*]; Bl[1]/CyO, P{w[+mC]=GAL4-Kr.C}DC3, P{w[+mC]=UAS-GFP.S65T}DC7; PBac{y[+mDint2] w[+mC]=brp(FRT.Stop)GFP}VK00033 (organism)
RRID:BDSC_55753
Drosophila melanogaster with name w[*]; Bl[1]/CyO, P{w[+mC]=GAL4-Kr.C}DC3, P{w[+mC]=UAS-GFP.S65T}DC7; PBac{y[+mDint2] w[+mC]=brp(FRT.Stop)GFP}VK00033 from BDSC.
View all literature mentionsw[1118] P{y[+t7.7] w[+mC]=hs-FLPG5.PEST}attP3; P{y[+t7.7] w[+mC]=10xUAS(FRT.stop)myr::smGdP-OLLAS}attP2 PBac{y[+mDint2] w[+mC]=10xUAS(FRT.stop)myr::smGdP-HA}VK00005 P{10xUAS(FRT.stop)myr::smGdP-V5-THS-10xUAS(FRT.stop)myr::smGdP-FLAG}su(Hw)attP1 (organism)
RRID:BDSC_64086
Drosophila melanogaster with name w[1118] P{y[+t7.7] w[+mC]=hs-FLPG5.PEST}attP3; P{y[+t7.7] w[+mC]=10xUAS(FRT.stop)myr::smGdP-OLLAS}attP2 PBac{y[+mDint2] w[+mC]=10xUAS(FRT.stop)myr::smGdP-HA}VK00005 P{10xUAS(FRT.stop)myr::smGdP-V5-THS-10xUAS(FRT.stop)myr::smGdP-FLAG}su(Hw)attP1 from BDSC.
View all literature mentionsw[*]; P{w[+mC]=UAS-MYC-Liprin-alpha.H}2/CyO (organism)
RRID:BDSC_63809
Drosophila melanogaster with name w[*]; P{w[+mC]=UAS-MYC-Liprin-alpha.H}2/CyO from BDSC.
View all literature mentionsy[1] w[1118]; P{w[+mC]=UAS-kirre.C-HA}2/CyO (organism)
RRID:BDSC_92196
Drosophila melanogaster with name y[1] w[1118]; P{w[+mC]=UAS-kirre.C-HA}2/CyO from BDSC.
View all literature mentionsP{w[+mC]=UAS-side.S}46, w[*] (organism)
RRID:BDSC_9679
Drosophila melanogaster with name P{w[+mC]=UAS-side.S}46, w[*] from BDSC.
View all literature mentionsw[1118]; P{w[+mC]=EP}side-VIII[EP2424] (organism)
RRID:BDSC_17248
Drosophila melanogaster with name w[1118]; P{w[+mC]=EP}side-VIII[EP2424] from BDSC.
View all literature mentionsy[1] v[1]; P{y[+t7.7] v[+t1.8]=TRiP.HMC03183}attP40 (organism)
RRID:BDSC_53868
Drosophila melanogaster with name y[1] v[1]; P{y[+t7.7] v[+t1.8]=TRiP.HMC03183}attP40 from BDSC.
View all literature mentionsy[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=TRiP.HMS00740}attP2 (organism)
RRID:BDSC_32946
Drosophila melanogaster with name y[1] sc[*] v[1] sev[21]; P{y[+t7.7] v[+t1.8]=TRiP.HMS00740}attP2 from BDSC.
View all literature mentionsw[1118]; P{GD14476}v27227 (organism)
RRID:Flybase_FBst0456824
Drosophila melanogaster with name w[1118]; P{GD14476}v27227 from Flybase.
View all literature mentionsP{KK106353}VIE-260B (organism)
RRID:Flybase_FBst0472832
Drosophila melanogaster with name P{KK106353}VIE-260B from Flybase.
View all literature mentionsw[1118]; P{GD2175}v44997/TM3 (organism)
RRID:Flybase_FBst0465867
Drosophila melanogaster with name w[1118]; P{GD2175}v44997/TM3 from Flybase.
View all literature mentionsw[1118]; P{GD5643}v16636 (organism)
RRID:Flybase_FBst0452368
Drosophila melanogaster with name w[1118]; P{GD5643}v16636 from Flybase.
View all literature mentionsw[1118]; P{GD12854}v22742 (organism)
RRID:Flybase_FBst0454672
Drosophila melanogaster with name w[1118]; P{GD12854}v22742 from Flybase.
View all literature mentionsP{KK101967}VIE-260B (organism)
RRID:Flybase_FBst0482037
Drosophila melanogaster with name P{KK101967}VIE-260B from Flybase.
View all literature mentionsw[1118]; P{GD321}v1283 (organism)
RRID:Flybase_FBst0450699
Drosophila melanogaster with name w[1118]; P{GD321}v1283 from Flybase.
View all literature mentionsP{KK106470}VIE-260B (organism)
RRID:Flybase_FBst0481835
Drosophila melanogaster with name P{KK106470}VIE-260B from Flybase.
View all literature mentionsw[1118]; P{GD6812}v27137 (organism)
RRID:Flybase_FBst0456776
Drosophila melanogaster with name w[1118]; P{GD6812}v27137 from Flybase.
View all literature mentionsP{KK104935}VIE-260B (organism)
RRID:Flybase_FBst0479711
Drosophila melanogaster with name P{KK104935}VIE-260B from Flybase.
View all literature mentionsy[1] v[1]; P{y[+t7.7] v[+t1.8]=TRiP.JF02909}attP2 (organism)
RRID:BDSC_28072
Drosophila melanogaster with name y[1] v[1]; P{y[+t7.7] v[+t1.8]=TRiP.JF02909}attP2 from BDSC.
View all literature mentionsy[1] v[1]; P{y[+t7.7] v[+t1.8]=UAS-LUC.VALIUM10}attP2 (organism)
RRID:BDSC_35788
Drosophila melanogaster with name y[1] v[1]; P{y[+t7.7] v[+t1.8]=UAS-LUC.VALIUM10}attP2 from BDSC.
View all literature mentionsw[1118]; P{w[+mC]=UAS-myr-mRFP}1 (organism)
RRID:BDSC_7118
Drosophila melanogaster with name w[1118]; P{w[+mC]=UAS-myr-mRFP}1 from BDSC.
View all literature mentionsw[1118]; P{w[+mC]=UAS-myr-mRFP}2/TM6B, Tb[1] (organism)
RRID:BDSC_7119
Drosophila melanogaster with name w[1118]; P{w[+mC]=UAS-myr-mRFP}2/TM6B, Tb[1] from BDSC.
View all literature mentionsw[*]; P{y[+t7.7] w[+mC]=10XUAS-IVS-mCD8::GFP}attP40 (organism)
RRID:BDSC_32186
Drosophila melanogaster with name w[*]; P{y[+t7.7] w[+mC]=10XUAS-IVS-mCD8::GFP}attP40 from BDSC.
View all literature mentionsy[1] w[*]; P{w[+mC]=UAS-FLP.D}JD1 (organism)
RRID:BDSC_4539
Drosophila melanogaster with name y[1] w[*]; P{w[+mC]=UAS-FLP.D}JD1 from BDSC.
View all literature mentionsP{w[+mC]=UAS-FLP.Exel}1, y[1] w[1118] (organism)
RRID:BDSC_8208
Drosophila melanogaster with name P{w[+mC]=UAS-FLP.Exel}1, y[1] w[1118] from BDSC.
View all literature mentionsw[1118]; P{y[+t7.7] w[+mC]=R37E10-GAL4.DBD}attP2 (organism)
RRID:BDSC_69000
Drosophila melanogaster with name w[1118]; P{y[+t7.7] w[+mC]=R37E10-GAL4.DBD}attP2 from BDSC.
View all literature mentionsw[1118]; P{y[+t7.7] w[+mC]=R64B07-p65.AD}attP40 (organism)
RRID:BDSC_71106
Drosophila melanogaster with name w[1118]; P{y[+t7.7] w[+mC]=R64B07-p65.AD}attP40 from BDSC.
View all literature mentionsw[1118]; P{y[+t7.7] w[+mC]=GMR31C06-GAL4}attP2 (organism)
RRID:BDSC_49883
Drosophila melanogaster with name w[1118]; P{y[+t7.7] w[+mC]=GMR31C06-GAL4}attP2 from BDSC.
View all literature mentionsw[1118]; P{y[+t7.7] w[+mC]=R34G07-GAL4.DBD}attP2 (organism)
RRID:BDSC_69029
Drosophila melanogaster with name w[1118]; P{y[+t7.7] w[+mC]=R34G07-GAL4.DBD}attP2 from BDSC.
View all literature mentionsw[1118]; P{y[+t7.7] w[+mC]=R31C06-p65.AD}attP40; MKRS/TM6B, Tb[1] (organism)
RRID:BDSC_70646
Drosophila melanogaster with name w[1118]; P{y[+t7.7] w[+mC]=R31C06-p65.AD}attP40; MKRS/TM6B, Tb[1] from BDSC.
View all literature mentionsw[1118]; P{y[+t7.7] w[+mC]=R14B07-GAL4.DBD}attP2 (organism)
RRID:BDSC_68940
Drosophila melanogaster with name w[1118]; P{y[+t7.7] w[+mC]=R14B07-GAL4.DBD}attP2 from BDSC.
View all literature mentionsw[1118]; P{y[+t7.7] w[+mC]=R64B03-p65.AD}attP40; P{y[+t7.7] w[+mC]=R29G08-GAL4.DBD}attP2 (organism)
RRID:BDSC_75895
Drosophila melanogaster with name w[1118]; P{y[+t7.7] w[+mC]=R64B03-p65.AD}attP40; P{y[+t7.7] w[+mC]=R29G08-GAL4.DBD}attP2 from BDSC.
View all literature mentionsw[1118]; P{y[+t7.7] w[+mC]=GMR16H03-GAL4}attP2 (organism)
RRID:BDSC_48744
Drosophila melanogaster with name w[1118]; P{y[+t7.7] w[+mC]=GMR16H03-GAL4}attP2 from BDSC.
View all literature mentionsw[1118]; P{y[+t7.7] w[+mC]=R66A01-GAL4.DBD}attP2 (organism)
RRID:BDSC_68999
Drosophila melanogaster with name w[1118]; P{y[+t7.7] w[+mC]=R66A01-GAL4.DBD}attP2 from BDSC.
View all literature mentionsw[1118]; P{y[+t7.7] w[+mC]=R48A08-p65.AD}attP40; MKRS/TM6B, Tb[1] (organism)
RRID:BDSC_70707
Drosophila melanogaster with name w[1118]; P{y[+t7.7] w[+mC]=R48A08-p65.AD}attP40; MKRS/TM6B, Tb[1] from BDSC.
View all literature mentionsw[1118]; P{w[+mC]=AyGAL4}17b (organism)
RRID:BDSC_4413
Drosophila melanogaster with name w[1118]; P{w[+mC]=AyGAL4}17b from BDSC.
View all literature mentionsw[1118]; P{w[+mC]=AyGAL4}25/CyO (organism)
RRID:BDSC_3953
Drosophila melanogaster with name w[1118]; P{w[+mC]=AyGAL4}25/CyO from BDSC.
View all literature mentionsw[*]; P{w[+mC]=longGMR-GAL4}2 (organism)
RRID:BDSC_8605
Drosophila melanogaster with name w[*]; P{w[+mC]=longGMR-GAL4}2 from BDSC.
View all literature mentions
