Isoxazole 9 (ISX9), a small molecule targeting Axin, activates Wnt/β-catenin signalling and promotes hair regrowth.
Isoxazole 9 (ISX9) is a neurogenesis-promoting small molecule compound that can up-regulate the expression of NeuroD1 and induce differentiation of neuronal, cardiac and islet endocrine progenitors. So far, the molecular mechanisms underlying the action of ISX9 still remain elusive.
Pubmed ID: 36721985 RIS Download
Research resources used in this publication
Additional research tools detected in this publication
None foundAntibodies used in this publication
- Ki-67 (D3B5) Rabbit mAb (Mouse Preferred; IHC Formulated) (RRID:AB_2620142)
- β-Catenin Antibody (RRID:AB_331149)
- Rabbit Anti-GSK-3 beta, phospho (Ser9) Monoclonal Antibody, Unconjugated, Clone D3A4 (RRID:AB_2115196)
- TWIST1 Antibody (RRID:AB_2799308)
- GSK-3beta (27C10) Rabbit mAb (RRID:AB_490890)
- Phospho-LRP6 (Ser1490) Antibody (RRID:AB_2139327)
- Goat anti-Mouse IgG (H+L) Secondary Antibody, HRP (RRID:AB_2534739)
- survivin (D-8) (RRID:AB_628302)
- V5-Tag (D3H8Q) Rabbit Antibody (RRID:AB_2687461)
- Rabbit Anti-Human Axin2 Monoclonal Antibody, Unconjugated, Clone 76G6 (RRID:AB_2062432)
- LEF1 (D6J2W) Rabbit mAb (RRID:AB_2799877)
- Goat anti-Rabbit IgG (H+L) Secondary Antibody, HRP (RRID:AB_2534770)
- Cytokeratin 17 antibody (RRID:AB_869865)
- Non-phospho (Active) β-Catenin (Ser33/37/Thr41) (D13A1) Rabbit mAb (RRID:AB_11127203)
- CK1ε Antibody (RRID:AB_2797919)
- LRP6 (C5C7) Rabbit mAb (RRID:AB_2139329)
- Lrrk2/Dardarin, N-terminus (RRID:AB_2315881)
- Monoclonal ANTI-FLAG® M2 antibody produced in mouse (RRID:AB_262044)
- Anti-Sox2 (D9B8N) Rabbit monoclonal Antibody (RRID:AB_2714146)
- Rabbit Anti-Human GPCR GPR49 Polyclonal Antibody, Unconjugated (RRID:AB_1310281)
- beta-catenin (E-5) (RRID:AB_626807)
Associated grants
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This is a list of tools and resources that we have found mentioned in this publication.
Ki-67 (D3B5) Rabbit mAb (Mouse Preferred; IHC Formulated) (antibody)
RRID:AB_2620142
This monoclonal targets Ki-67
View all literature mentionsβ-Catenin Antibody (antibody)
RRID:AB_331149
This polyclonal targets β-Catenin
View all literature mentionsRabbit Anti-GSK-3 beta, phospho (Ser9) Monoclonal Antibody, Unconjugated, Clone D3A4 (antibody)
RRID:AB_2115196
This monoclonal targets Gsk3b
View all literature mentionsGSK-3beta (27C10) Rabbit mAb (antibody)
RRID:AB_490890
This monoclonal targets GSK-3beta (27C10) Rabbit mAb
View all literature mentionsPhospho-LRP6 (Ser1490) Antibody (antibody)
RRID:AB_2139327
This polyclonal targets Phospho-LRP6 (Ser1490)
View all literature mentionsGoat anti-Mouse IgG (H+L) Secondary Antibody, HRP (antibody)
RRID:AB_2534739
This polyclonal secondary targets IgG (H+L)
View all literature mentionssurvivin (D-8) (antibody)
RRID:AB_628302
This monoclonal targets survivin (D-8)
View all literature mentionsV5-Tag (D3H8Q) Rabbit Antibody (antibody)
RRID:AB_2687461
This monoclonal targets V5-Tag
View all literature mentionsRabbit Anti-Human Axin2 Monoclonal Antibody, Unconjugated, Clone 76G6 (antibody)
RRID:AB_2062432
This monoclonal targets Human Axin2
View all literature mentionsLEF1 (D6J2W) Rabbit mAb (antibody)
RRID:AB_2799877
This monoclonal targets LEF-1
View all literature mentionsGoat anti-Rabbit IgG (H+L) Secondary Antibody, HRP (antibody)
RRID:AB_2534770
This polyclonal secondary targets IgG (H+L)
View all literature mentionsCytokeratin 17 antibody (antibody)
RRID:AB_869865
This polyclonal targets Cytokeratin 17
View all literature mentionsNon-phospho (Active) β-Catenin (Ser33/37/Thr41) (D13A1) Rabbit mAb (antibody)
RRID:AB_11127203
This unknown targets Non-phospho (Active) β-Catenin (Ser33/37/Thr41) (D13A1) Rabbit mAb
View all literature mentionsLRP6 (C5C7) Rabbit mAb (antibody)
RRID:AB_2139329
This monoclonal targets LRP6
View all literature mentionsLrrk2/Dardarin, N-terminus (antibody)
RRID:AB_2315881
This monoclonal targets Lrrk2/Dardarin, N-terminus
View all literature mentionsMonoclonal ANTI-FLAG® M2 antibody produced in mouse (antibody)
RRID:AB_262044
This monoclonal targets FLAG
View all literature mentionsAnti-Sox2 (D9B8N) Rabbit monoclonal Antibody (antibody)
RRID:AB_2714146
This monoclonal targets Sox2
View all literature mentionsRabbit Anti-Human GPCR GPR49 Polyclonal Antibody, Unconjugated (antibody)
RRID:AB_1310281
This polyclonal targets Human GPCR GPR49
View all literature mentionsbeta-catenin (E-5) (antibody)
RRID:AB_626807
This monoclonal targets Raised against amino acids 680-781 mapping at the C-terminus of b-Cat o human origin
View all literature mentionsGraphPad (commercial organization)
RRID:SCR_000306
A commercial graphing software company that offers scientific software for statistical analyses, curve fitting and data analysis. It offers four programs: Prism, InStat, StatMate and QuickCalcs.
View all literature mentionsNIH 3T3 (cell line)
RRID:CVCL_0594
Cell line NIH 3T3 is a Spontaneously immortalized cell line with a species of origin Mus musculus
View all literature mentionsHaCaT (cell line)
RRID:CVCL_0038
Cell line HaCaT is a Spontaneously immortalized cell line with a species of origin Homo sapiens (Human)
View all literature mentionsHEK293T (cell line)
RRID:CVCL_0063
Cell line HEK293T is a Transformed cell line with a species of origin Homo sapiens (Human)
View all literature mentions
