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Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis.

Neus Martínez-Bosch | Helena Cristóbal | Mar Iglesias | Meritxell Gironella | Luis Barranco | Laura Visa | Domenico Calafato | Silvia Jiménez-Parrado | Julie Earl | Alfredo Carrato | Noemí Manero-Rupérez | Mireia Moreno | Albert Morales | Carmen Guerra | Pilar Navarro | Pablo García de Frutos
EBioMedicine | 2022

Early diagnosis is crucial for patients with pancreatic ductal adenocarcinoma (PDAC). The AXL receptor tyrosine kinase is proteolytically processed releasing a soluble form (sAXL) into the blood stream. Here we explore the use of sAXL as a biomarker for PDAC.

Pubmed ID: 34973624 RIS Download

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Axl (C-20) (antibody)

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IgG from goat serum (antibody)

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Capan-1 (cell line)

RRID:CVCL_0237

Cell line Capan-1 is a Cancer cell line with a species of origin Homo sapiens (Human)

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RWP-1 (cell line)

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Cell line RWP-1 is a Cancer cell line with a species of origin Homo sapiens (Human)

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Hs 766T (cell line)

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Cell line Hs 766T is a Cancer cell line with a species of origin Homo sapiens (Human)

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RRID:CVCL_0480

Cell line PANC-1 is a Cancer cell line with a species of origin Homo sapiens (Human)

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Cell line SK-PC-1 is a Cancer cell line with a species of origin Homo sapiens (Human)

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