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Tanshinol borneol ester, a novel synthetic small molecule angiogenesis stimulator inspired by botanical formulations for angina pectoris.

Sha Liao | Liwen Han | Xiaopu Zheng | Xin Wang | Peng Zhang | Jingni Wu | Ruimin Liu | Youlan Fu | Jiaxin Sun | Ximeng Kang | Kechun Liu | Tai-Ping Fan | Shao Li | Xiaohui Zheng
British journal of pharmacology | 2019

Tanshinol borneol ester (DBZ) is a novel synthetic compound derived from Dantonic® , a botanical drug approved in 26 countries outside the United States for angina pectoris and currently undergoing FDA Phase III clinical trial. Here, we investigated the angiogenic effects of (S)-DBZ and (R)-DBZ isomers in vitro and in vivo.

Pubmed ID: 31116880 RIS Download

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