Generation of induced pluripotent stem cell line-NTUHi001-A from a premature ovarian failure patient with Turner's syndrome mosaicism.
Turner's syndrome (TS) is one of the main causes of premature ovarian failure (POF). However, the mechanisms underlying POF are difficult to study due to the lack of suitable disease models. Herein, we have generated a human induced pluripotent stem cell (hiPSC) line derived from the peripheral blood mononuclear cells of a female patient with Turner's syndrome mosaicism via integration-free Sendai-virus system. The hiPSCs were confirmed with a 45, X karyotype and the acquisition of pluripotency. It's likely that hiPSCs can serve as a feasible cellular model for further pathophysiological studies of POF cases, especially for those originating in TS.
Pubmed ID: 31004936
Research resources used in this publication
None foundAdditional research tools detected in this publication
Antibodies used in this publication
- 3-Germ Layer Immunocytochemistry Kit (RRID:AB_2651003)
- 3-Germ Layer Immunocytochemistry Kit (RRID:AB_2651012)
- Pluripotent Stem Cell 4-Marker Immunocytochemistry Kit (RRID:AB_2651008)
- 3-Germ Layer Immunocytochemistry Kit (RRID:AB_2651010)
- Pluripotent Stem Cell 4-Marker Immunocytochemistry Kit (RRID:AB_2651007)
- Pluripotent Stem Cell 4-Marker Immunocytochemistry Kit (RRID:AB_2651009)
- 3-Germ Layer Immunocytochemistry Kit (RRID:AB_2651011)
- 3-Germ Layer Immunocytochemistry Kit (RRID:AB_2651004)
- Mouse Anti-Human Nanog Monoclonal Antibody, PE Conjugated (RRID:AB_1645522)
- 3-Germ Layer Immunocytochemistry Kit (RRID:AB_2651005)
- Pluripotent Stem Cell 4-Marker Immunocytochemistry Kit (RRID:AB_2651006)
- Mouse Anti-Human TRA-1-81 Antigen Monoclonal Antibody, PE Conjugated (RRID:AB_1645540)
- Oct3/4 (RRID:AB_1645331)
- Sox2 (RRID:AB_1645334)
- Mouse Anti-Human TRA-1-60 Antigen Monoclonal Antibody, PE Conjugated (RRID:AB_1645539)
- Mouse Anti-Human SSEA-4 Monoclonal Antibody, PE Conjugated (RRID:AB_1645533)
- Pluripotent Stem Cell 4-Marker Immunocytochemistry Kit (RRID:AB_2651002)
- Pluripotent Stem Cell 4-Marker Immunocytochemistry Kit (RRID:AB_2651001)
- Pluripotent Stem Cell 4-Marker Immunocytochemistry Kit (RRID:AB_2650999)
- Pluripotent Stem Cell 4-Marker Immunocytochemistry Kit (RRID:AB_2651000)
Associated grants
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This is a list of tools and resources that we have found mentioned in this publication.
3-Germ Layer Immunocytochemistry Kit (antibody)
RRID:AB_2651003
This unknown targets
View all literature mentions3-Germ Layer Immunocytochemistry Kit (antibody)
RRID:AB_2651012
This unknown targets
View all literature mentionsPluripotent Stem Cell 4-Marker Immunocytochemistry Kit (antibody)
RRID:AB_2651008
This unknown targets
View all literature mentions3-Germ Layer Immunocytochemistry Kit (antibody)
RRID:AB_2651010
This unknown targets
View all literature mentionsPluripotent Stem Cell 4-Marker Immunocytochemistry Kit (antibody)
RRID:AB_2651007
This unknown targets
View all literature mentionsPluripotent Stem Cell 4-Marker Immunocytochemistry Kit (antibody)
RRID:AB_2651009
This unknown targets
View all literature mentions3-Germ Layer Immunocytochemistry Kit (antibody)
RRID:AB_2651011
This unknown targets
View all literature mentions3-Germ Layer Immunocytochemistry Kit (antibody)
RRID:AB_2651004
This unknown targets
View all literature mentionsMouse Anti-Human Nanog Monoclonal Antibody, PE Conjugated (antibody)
RRID:AB_1645522
This monoclonal targets Nanog
View all literature mentions3-Germ Layer Immunocytochemistry Kit (antibody)
RRID:AB_2651005
This unknown targets
View all literature mentionsPluripotent Stem Cell 4-Marker Immunocytochemistry Kit (antibody)
RRID:AB_2651006
This unknown targets
View all literature mentionsMouse Anti-Human TRA-1-81 Antigen Monoclonal Antibody, PE Conjugated (antibody)
RRID:AB_1645540
This monoclonal targets TRA-1-81 Antigen
View all literature mentionsMouse Anti-Human TRA-1-60 Antigen Monoclonal Antibody, PE Conjugated (antibody)
RRID:AB_1645539
This monoclonal targets Human TRA-1-60 Antigen
View all literature mentionsMouse Anti-Human SSEA-4 Monoclonal Antibody, PE Conjugated (antibody)
RRID:AB_1645533
This monoclonal targets Human SSEA-4
View all literature mentionsPluripotent Stem Cell 4-Marker Immunocytochemistry Kit (antibody)
RRID:AB_2651002
This unknown targets
View all literature mentionsPluripotent Stem Cell 4-Marker Immunocytochemistry Kit (antibody)
RRID:AB_2651001
This unknown targets
View all literature mentionsPluripotent Stem Cell 4-Marker Immunocytochemistry Kit (antibody)
RRID:AB_2650999
This unknown targets
View all literature mentionsPluripotent Stem Cell 4-Marker Immunocytochemistry Kit (antibody)
RRID:AB_2651000
This polyclonal targets
View all literature mentions
