URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=48037
Proper Citation: RRID:MMRRC_048037-UCD
Description: Mus musculus with name C57BL/6N-Atm1Brd Hbs1ltm1a(KOMP)Wtsi/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: KOMP
Phenotype: decreased bone mineral density [MP:0000063]| decreased monocyte cell number [MP:0000223]| abnormal cranium morphology [MP:0000438]| abnormal snout morphology [MP:0000443]| short snout [MP:0000445]| increased rib number [MP:0000480]| decreased body length [MP:0001258]| abnormal cornea morphology [MP:0001312]| corneal opacity [MP:0001314]| abnormal retina morphology [MP:0001325]| male infertility [MP:0001925]| increased mean corpuscular volume [MP:0002590]| increased mean platelet volume [MP:0002599]| increased circulating alkaline phosphatase level [MP:0002968]| vertebral transformation [MP:0003036]| abnormal lumbar vertebrae morphology [MP:0003049]| abnormal bone structure [MP:0003795]| increased lean body mass [MP:0003960]| decreased lean body mass [MP:0003961]| decreased eosinophil cell number [MP:0005012]| increased T cell number [MP:0005015]| abnormal retinal pigmentation [MP:0005103]| improved glucose tolerance [MP:0005292]| increased mean corpuscular hemoglobin [MP:0005561]| increased circulating total protein level [MP:0005568]| increased NK cell number [MP:0008044]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008346]| increased gamma-delta T cell number [MP:0008810]| increased circulating iron level [MP:0010025]| decreased total body fat amount [MP:0010067]| increased red blood cell distribution width [MP:0010124]| decreased bone mineral content [MP:0010168]| increased CD4-positive [MP:0010844]| CD25-positive [MP:0010851]| alpha-beta regulatory T cell number [MP:0012764]| increased effector memory CD4-positive [MP:0013023]| alpha-beta T cell number [MP:0013157]| decreased effector memory CD8-positive [MP:0013764]
Affected Gene: |Hbs1l|
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
