URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=42298
Proper Citation: RRID:MMRRC_042298-UCD
Description: Mus musculus with name B6J.129-Atoh7tm1Gla/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Developmental Biology, Models for Human Disease, Neurobiology, Research Tools, Sensorineural; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal retinal cone cell morphology [MP:0001006]| abnormal eye development [MP:0001286]| abnormal retina morphology [MP:0001325]| abnormal optic nerve morphology [MP:0001330]| abnormal optic nerve innervation [MP:0001332]| absent optic nerve [MP:0001333]| absent optic tract [MP:0001334]| abnormal blood vessel morphology [MP:0001614]| abnormal retinal vasculature morphology [MP:0002792]| abnormal cell cycle [MP:0003077]| abnormal optic vesicle formation [MP:0003425]| abnormal amacrine cell morphology [MP:0005240]| abnormal retinal ganglion layer morphology [MP:0005241]| abnormal eye electrophysiology [MP:0005551]| abnormal retinal bipolar cell morphology [MP:0006073]| abnormal retinal rod bipolar cell morphology [MP:0006074]| abnormal retinal cone bipolar cell morphology [MP:0006075]| abnormal retinal nerve fiber layer morphology [MP:0006303]| absent retinal ganglion cell [MP:0008068]| increased retinal cone cell number [MP:0008445]| decreased retinal rod cell number [MP:0008453]| absent retinal ganglion layer [MP:0008510]| thin retinal inner nuclear layer [MP:0008511]| thin retinal inner plexiform layer [MP:0008513]| thin retinal outer nuclear layer [MP:0008515]| thin retinal outer plexiform layer [MP:0008519]| decreased total retina thickness [MP:0011965]| abnormal circardian behavior entrainment [MP:0020476]
Affected Gene: Atoh7
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
