URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=36548
Proper Citation: RRID:MMRRC_036548-UNC
Description: Mus musculus with name STOCK Smarca4tm1.2Pcn/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Developmental Biology, Immunology and Inflammation; Mutation Type: other ; Collection:
Phenotype: enlarged heart [MP:0000274]| abnormal atrioventricular cushion morphology [MP:0000297]| abnormal digestive system morphology [MP:0000462]| abnormal intestine morphology [MP:0000477]| abnormal small intestine morphology [MP:0000496]| abnormal urinary bladder morphology [MP:0000538]| abnormal hindlimb morphology [MP:0000556]| increased thymocyte number [MP:0000714]| decreased thymocyte number [MP:0000715]| absent CD8-positive [MP:0000727]| alpha-beta T cells [MP:0000740]| impaired smooth muscle contractility [MP:0001196]| shiny skin [MP:0001237]| enlarged spinous cells [MP:0001239]| abnormal epidermis stratum granulosum morphology [MP:0001240]| abnormal epidermis stratum corneum morphology [MP:0001575]| cyanosis [MP:0001676]| abnormal apical ectodermal ridge morphology [MP:0001823]| thymus hypoplasia [MP:0001825]| arrested T cell differentiation [MP:0002060]| abnormal skin morphology [MP:0002081]| perinatal lethality [MP:0002106]| abnormal muscle physiology [MP:0002110]| abnormal digit morphology [MP:0002145]| abnormal T cell differentiation [MP:0002295]| abnormal pulmonary circulation [MP:0002731]| megacolon [MP:0002746]| abnormal semilunar valve morphology [MP:0002747]| abnormal aortic valve morphology [MP:0002796]| impaired skin barrier function [MP:0003139]| patent ductus arteriosus [MP:0003800]| monodactyly [MP:0003853]| dry skin [MP:0003857]| abnormal hindlimb zeugopod morphology [MP:0004002]| abnormal jejunum morphology [MP:0004111]| abnormal coronary artery morphology [MP:0004937]| dilated heart [MP:0005089]| decreased double-negative T cell number [MP:0005090]| increased double-negative T cell number [MP:0005092]| decreased double-positive T cell number [MP:0005294]| abnormal heart ventricle morphology [MP:0005330]| cardiomyopathy [MP:0006126]| abnormal cardiac outflow tract development [MP:0006138]| congestive heart failure [MP:0008037]| abnormal T cell morphology [MP:0008075]| decreased CD4-positive [MP:0008802]| alpha beta T cell number [MP:0009476]| abnormal intestinal smooth muscle morphology [MP:0009483]| enlarged cecum [MP:0010402]| enlarged ileum [MP:0010418]| ventricular septal defect [MP:0010453]| perimembraneous ventricular septal defect [MP:0010482]| abnormal coronary vein morphology [MP:0010484]| abnormal aortic sinus morphology [MP:0010593]| bicuspid aortic valve [MP:0010594]| thick aortic valve cusps [MP:0010595]| thick aortic valve [MP:0010601]| abnormal aortic valve cusp morphology [MP:0010602]| thick pulmonary valve [MP:0010656]| abnormal pulmonary valve cusp morphology [MP:0010819]| thick myocardium [MP:0010998]| primary atelectasis [MP:0011085]| pulmonary alveolar proteinosis [MP:0011086]| postnatal lethality [MP:0011087]| complete penetrance [MP:0011109]| postnatal lethality [MP:0011648]| incomplete penetrance [MP:0013956]| neonatal lethality [MP:0013958]
Affected Gene: Smarca4
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
