URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=29877
Proper Citation: RRID:MMRRC_029877-MU
Description: Mus musculus with name B6.129S6-Klf4tm1Khk/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Cell Biology, Developmental Biology; Mutation Type: Targeted Mutation ; Collection: BCBC-Beta Cell Biology Consortium
Phenotype: abnormal hair follicle morphology [MP:0000377]| abnormal esophageal epithelium morphology [MP:0000468]| abnormal stomach epithelium morphology [MP:0000471]| abnormal intestinal epithelium morphology [MP:0000488]| abnormal tongue squamous epithelium morphology [MP:0000765]| skin lesions [MP:0001212]| microphthalmia [MP:0001297]| small lens [MP:0001306]| small pupils [MP:0001320]| impaired wound healing [MP:0001792]| preneoplasia [MP:0002009]| abnormal skin morphology [MP:0002060]| abnormal eye morphology [MP:0002092]| no abnormal phenotype detected [MP:0002169]| abnormal keratinocyte morphology [MP:0002655]| abnormal keratinocyte differentiation [MP:0002656]| decreased circulating testosterone level [MP:0002780]| abnormal testes secretion [MP:0002782]| abnormal lens fiber morphology [MP:0002840]| decreased corneal stroma thickness [MP:0003092]| abnormal cornea anterior stroma morphology [MP:0003093]| gastric hypertrophy [MP:0003285]| abnormal intestinal goblet cell morphology [MP:0003449]| abnormal gastric gland morphology [MP:0003892]| abnormal Sertoli cell development [MP:0004109]| abnormal gastric surface mucous cell morphology [MP:0004137]| abnormal mucous neck cell morphology [MP:0004138]| abnormal gastric parietal cell morphology [MP:0004139]| abnormal gastric chief cell morphology [MP:0004140]| abnormal conjunctival epithelium morphology [MP:0004481]| increased incidence of tumors by chemical induction [MP:0004499]| eyelids fail to open [MP:0005176]| blepharitis [MP:0005251]| abnormal corneal stroma morphology [MP:0005300]| abnormal corneal endothelium morphology [MP:0005301]| abnormal corneal epithelium morphology [MP:0006000]| abnormal seminiferous tubule size [MP:0006307]| abnormal Bowman membrane [MP:0008521]| increased keratinocyte proliferation [MP:0009583]| thick epidermis suprabasal layer [MP:0009612]| increased corneal stroma thickness [MP:0009742]| focal ventral hair loss [MP:0010203]| abnormal stomach mucosa morphology [MP:0010792]| vacuolated lens [MP:0011697]| abnormal seminiferous tubule epithelium morphology [MP:0011750]| acoria [MP:0012101]| increased hair follicle number [MP:0012110]| increased keratinocyte migration [MP:0012193]| decreased Ly6C low monocyte number [MP:0013026]| increased Paneth cell number [MP:0013485]| absent conjunctiva goblet cells [MP:0013527]| abnormal ocular surface morphology [MP:0013754]| iris hyperplasia [MP:0013765]| ectopic Paneth cells [MP:0014077]| increased keratinocyte adhesion [MP:0030577]
Affected Gene: Klf4
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
