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Proper Citation: RRID:MGI:3577712
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal enterocyte morphology, decreased susceptibility to parasitic infection, decreased interferon-gamma secretion, decreased tumor necrosis factor secretion, decreased interleukin-12b secretion, increased dendritic cell number, decreased tumor necrosis factor secretion, decreased interleukin-12 secretion, abnormal macrophage physiology, decreased interleukin-12b secretion, decreased interferon-gamma secretion, abnormal dendritic cell physiology, abnormal dendritic cell physiology, abnormal cytokine secretion, abnormal T cell physiology, increased susceptibility to viral infection, decreased interferon-alpha secretion, decreased interleukin-6 secretion, abnormal nervous system physiology, abnormal chemokine secretion, abnormal NK cell physiology, increased physiological sensitivity to xenobiotic, abnormal dendritic cell differentiation, increased apoptosis, abnormal response to infection, abnormal neuron differentiation, abnormal susceptibility to hearing loss, decreased susceptibility to kidney reperfusion injury, rectal hemorrhage, decreased inflammatory response, decreased interleukin-6 secretion, decreased tumor necrosis factor secretion, abnormal immune system physiology
Affected Gene: Myd88
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI