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Proper Citation: RRID:MGI:3522138
Description: Allele Detail: Targeted, Transgenic This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted, Transgenic This is a legacy resource.
Phenotype: decreased body temperature, obese, increased circulating corticosterone level, increased liver triglyceride level, increased liver glycogen level, increased circulating triglyceride level, increased circulating leptin level, increased circulating thyroid-stimulating hormone level, increased brown adipose tissue amount, increased body length, hypoglycemia, hypersecretion of corticosterone, hyperglycemia, hepatic steatosis, reduced female fertility, increased circulating growth hormone level, increased circulating insulin level, increased white adipose tissue amount, decreased circulating thyroxine level, decreased circulating triiodothyronine level, abnormal circulating hormone level, abnormal glucose homeostasis, abnormal liver morphology, enlarged liver, increased susceptibility to weight gain
Affected Gene: Ptpn11
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No rating or validation information has been found for Tg(Camk2a-cre)2Szi; Ptpn11tm1Gsf/Ptpn11tm1Gsf.
No alerts have been found for Tg(Camk2a-cre)2Szi; Ptpn11tm1Gsf/Ptpn11tm1Gsf.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI