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Organism Name
RRID:IMSR_EM:00064 RRID Copied  
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RRID:IMSR_EM:00064
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Organism Information

URL: https://www.infrafrontier.eu/emma/strain-search/straindetails/?q=64

Proper Citation: RRID:IMSR_EM:00064

Description: Mus musculus with name B6;129S7-Prnptm1Cwe Tg(Prnp)e19hCwe/CweCnrm from IMSR.

Species: Mus musculus

Synonyms: PrPC-KO. E1931. B6;129S7-Prnp Tg(Prnp)e19hCwe/CweIbcm. B6;129S7 Prnp-Tg(Prnp)e19hCwe/Cwe. E1931-Tg. STOCK Prnp Tg(Prnp)E1931Cwe

Notes: gene symbol note: prion protein|transgene insertion e19h; Charles Weissmann; mutant strain: Prnp|Tg(Prnp)e19hCwe

Affected Gene: prion protein|transgene insertion e19h; Charles Weissmann

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Ratings and Alerts

No rating or validation information has been found for B6;129S7-Prnptm1Cwe Tg(Prnp)e19hCwe/CweCnrm.

Issue
Warning. Researchers have noted that this genotype does not sufficiently model human Creutzfeldt-Jakob disease.

Issue
Warning. Researchers have noted that this genotype does not sufficiently model human Gerstmann-Straussler-Scheinker syndrome.

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Data and Source Information

Source: Integrated Animals

Source Database: International Mouse Resource Center IMSR, EMMA