URL: https://web.expasy.org/cellosaurus/CVCL_2632
Proper Citation: (JCRB Cat# JCRB0135, RRID:CVCL_2632)
Description: Cell line MT-4 is a Transformed cell line with a species of origin Homo sapiens
Sex: Male
Defining Citation: PMID:1364232, PMID:1765142, PMID:2413616, PMID:8927062, PMID:8957066, PMID:9261343, PMID:29892436, PMID:31554688, PMID:32938764
Comments: Derived from sampling site: Umbilical cord blood. Cell type=T-cell., Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1)., Doubling time: ~30 hours (lot 102799) (JCRB)., Virology: HTLV-1 producing cell line. Expresses Tax. Is permissive for replication of an HIV-1 gp41 mutant lacking the cytoplasmic tail., Characteristics: Was established by co-cultivation of cells from a 50 year old male T-cell leukemia patient with cord leukocytes from a male infant (CelloPub=CLPUB00542)., Population: Japanese., Problematic cell line: Partially contaminated. Two different lots formerly distributed by NIH-ARP; 13 P7 3/9/92 and 150048; were shown not to be authentic MT-4 (PubMed=9261343; PubMed=31554688).., Discontinued: JCRB; NIHS0145; true., Discontinued: JCRB; NIHS0529; true.
Category: Transformed cell line
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Partially Contaminated
Problematic cell line: Partially contaminated. Two different lots formerly distributed by NIH-ARP; 13 P7 3/9/92 and 150048; were shown not to be authentic MT-4 (PubMed=9261343; PubMed=31554688).
Discontinued
Discontinued: JCRB; NIHS0145
Discontinued
Discontinued: JCRB; NIHS0529
Source: Cellosaurus