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Goat anti-Mouse IgG3 Cross-Adsorbed Secondary Antibody, Alexa Fluor 488

RRID:AB_2535784

Antibody ID

AB_2535784

Target Antigen

Mouse IgG3 Cross-Adsorbed mouse

Proper Citation

(Thermo Fisher Scientific Cat# A-21151, RRID:AB_2535784)

Clonality

polyclonal antibody

Comments

Applications: IHC (1-10 µg/mL), IF (1-10 µg/mL), ICC (1-10 µg/mL), Flow (1-10 µg/mL)

Host Organism

goat

Vendor

Thermo Fisher Scientific Go To Vendor

Cat Num

A-21151

Publications that use this research resource

Generation of 3 spinocerebellar ataxia type 1 (SCA1) patient-derived induced pluripotent stem cell lines LUMCi002-A, B, and C and 2 unaffected sibling control induced pluripotent stem cell lines LUMCi003-A and B.

  • Buijsen RAM
  • Stem Cell Res
  • 2018 Apr 16

Literature context:


Abstract:

Spinocerebellar ataxia type 1 (SCA1) is a hereditary neurodegenerative disease caused by a CAG repeat expansion in exon 8 of the ATXN1 gene. We generated induced pluripotent stem cells (hiPSCs) from a SCA1 patient and his non-affected sister by using non-integrating Sendai Viruses (SeV). The resulting hiPSCs are SeVfree, express pluripotency markers, display a normal karyotype, retain the mutation (length of the CAG repeat expansion in the ATXN1 gene) and are able to differentiate into the three germ layers in vitro.

Funding information:
  • NIAID NIH HHS - T32 AI007638-09(United States)