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MDA-MB-231

RRID:CVCL-0062

Organism

Homo sapiens

Comments

Group: Triple negative breast cancer (TNBC) cell line. Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Part of: ENCODE project common cell types; tier 3. Part of: ICBP43 breast cancer cell line panel. Part of: JFCR39 cancer cell line panel. Part of: JFCR45 cancer cell line panel. Part of: KuDOS 95 cell line panel. Part of: MD Anderson Cell Lines Project. Part of: NCI-60 cancer cell line panel. Registration: Chiron Master Culture Collection; CMCC 10583 (CMCC #10583). Doubling time: 1.3 days (PubMed=9671407); 41.9 hours (NCI-DTP); 38 hours (ATCC); ~25-30 hours (DSMZ); ~38 hours (PBCF). HLA typing: A*02:01,02:17; B*40:02,41:01; C*02:02:02,17; DPB1*02:01:02,17:01; DQB1*02:02,03:01:01; DRB1*07:01,13:05 (PubMed=15748285). HLA typing: A*02:17,02:01; B*41:01,40:02; C*17:01,02:02; DQA1*02:01,02:01; DQB1*03:04,03:04; DRB1*13:05,07:01 (PubMed=25960936). Microsatellite instability: Stable (MSS) (PubMed=12661003; Sanger). Sequence variation: Heterozygous for BRAF p.Gly464Val (c.1391G>T) (PubMed=17088437; PubMed=19593635; ATCC). Sequence variation: Homozygous for CDKN2A deletion (PubMed=19593635; ATCC). Sequence variation: Heterozygous for KRAS p.Gly13Asp (c.38G>A) (PubMed=12068308; PubMed=17088437; PubMed=19593635; ATCC). Sequence variation: TERT c.228C>T (-124C>T); in promoter (PubMed=31068700). Sequence variation: Homozygous for TP53 p.Arg280Lys (c.839G>A) (PubMed=15900046; PubMed=16541312; PubMed=17088437; PubMed=18277095; PubMed=28889351; ATCC). Omics: Array-based CGH. Omics: Cell surface proteome. Omics: CNV analysis. Omics: Deep exome analysis. Omics: Deep proteome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: Fluorescence phenotype profiling. Omics: Glycoproteome analysis by proteomics. Omics: lncRNA expression profiling. Omics: Metabolome analysis. Omics: miRNA expression profiling. Omics: N-glycan profiling. Omics: Protein expression by reverse-phase protein arrays. Omics: Secretome proteome analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Genome ancestry: African=1.95%; Native American=0%; East Asian, North=2.44%; East Asian, South=0%; South Asian=7.42%; European, North=28.16%; European, South=60.03% (PubMed=30894373). Misspelling: MDA-MD-231; In Cosmic 1071900 and Cosmic 1176602. Misspelling: MDA-321; In GEO GSM459713. Misspelling: MDA-MG-231; In PubMed=6582512. Misspelling: MD-MB-231; In PRIDE PXD010634. Misspelling: MD-MBA-231; Occasionally. Discontinued: ATCC; CRL-12532. Discontinued: CLS; 300275. Derived from metastatic site: Pleural effusion. DT Created: 04-04-12; Last updated: 05-07-19; Version: 31

Proper Citation

CLS Cat# 300275/NA, RRID:CVCL_0062

Category

Cancer cell line DT Created: 04-04-12; Last updated: 05-07-19; Version: 31

Sex

DT Created: 04-04-12; Last updated: 05-07-19; Version: 31

Synonyms

MDA-MB 231, MDA.MB.231, MDA MB 231, MDA MB231, MDA Mb231, MDA-MB231, MDAMB-231, MDAMB231, MDA-231, MDA231, MB231, MD Anderson-Metastatic Breast-231 DT Created: 04-04-12, Last updated: 05-07-19, Version: 31

Vendor

CLS

Cat Num

300275/NA

Cross References

BTO; BTO:0000815 CLO; CLO_0007634 CLO; CLO_0037291 EFO; EFO_0001209 MCCL; MCC:0000313 CLDB; cl3402 CLDB; cl3404 CLDB; cl3405 CLDB; cl4945 AddexBio; C0006002/58 ArrayExpress; E-MTAB-2706 ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 ArrayExpress; E-TABM-157 ArrayExpress; E-TABM-244 ATCC; CRL-12532 ATCC; HTB-26 ATCC; CRM-HTB-26 BCRC; 60425 BCRJ; 0164 BioSample; SAMN03472205 BioSample; SAMN05292460 BioSample; SAMN07710033 BioSample; SAMN07710034 BioSample; SAMN07710035 BioSample; SAMN07710036 BioSample; SAMN07710037 BioSample; SAMN07710038 BioSample; SAMN07710039 BioSample; SAMN10987764 CCLE; MDAMB231_BREAST CCRID; 3111C0001CCC000014 CCRID; 3131C0001000700104 CCTCC; GDC0297 Cell_Model_Passport; SIDM00146 ChEMBL-Cells; CHEMBL3307960 ChEMBL-Targets; CHEMBL400 CLS; 300275/NA Cosmic; 687494 Cosmic; 871146 Cosmic; 875878 Cosmic; 877450 Cosmic; 894087 Cosmic; 897423 Cosmic; 904377 Cosmic; 905960 Cosmic; 934536 Cosmic; 944294 Cosmic; 974235 Cosmic; 991324 Cosmic; 997929 Cosmic; 1010924 Cosmic; 1018477 Cosmic; 1027053 Cosmic; 1044226 Cosmic; 1046950 Cosmic; 1047693 Cosmic; 1071900 Cosmic; 1092613 Cosmic; 1136369 Cosmic; 1152528 Cosmic; 1175833 Cosmic; 1176602 Cosmic; 1176636 Cosmic; 1183773 Cosmic; 1219444 Cosmic; 1287926 Cosmic; 1289395 Cosmic; 1305383 Cosmic; 1309003 Cosmic; 1312370 Cosmic; 1434952 Cosmic; 1436032 Cosmic; 1466805 Cosmic; 1477428 Cosmic; 1481426 Cosmic; 1524347 Cosmic; 1571793 Cosmic; 1609458 Cosmic; 1927242 Cosmic; 1945862 Cosmic; 1998455 Cosmic; 2009512 Cosmic; 2036667 Cosmic; 2164997 Cosmic; 2301528 Cosmic; 2318377 Cosmic; 2361355 Cosmic; 2560256 Cosmic-CLP; 905960 DepMap; ACH-000768 DSMZ; ACC-732 ECACC; 92020424 FCS-free; 253-2-521-2-3-3 GDSC; 905960 GEO; GSM812 GEO; GSM2124 GEO; GSM49953 GEO; GSM49954 GEO; GSM50184 GEO; GSM50248 GEO; GSM69194 GEO; GSM155213 GEO; GSM185093 GEO; GSM185094 GEO; GSM274653 GEO; GSM344349 GEO; GSM344399 GEO; GSM350547 GEO; GSM378148 GEO; GSM388213 GEO; GSM421873 GEO; GSM459713 GEO; GSM481304 GEO; GSM587393 GEO; GSM587394 GEO; GSM750781 GEO; GSM799321 GEO; GSM799384 GEO; GSM820814 GEO; GSM820815 GEO; GSM820816 GEO; GSM847036 GEO; GSM847401 GEO; GSM844594 GEO; GSM844595 GEO; GSM887295 GEO; GSM888370 GEO; GSM967818 GEO; GSM1008905 GEO; GSM1053716 GEO; GSM1153390 GEO; GSM1172979 GEO; GSM1172889 GEO; GSM1181242 GEO; GSM1181365 GEO; GSM1214569 GEO; GSM1238120 GEO; GSM1374651 GEO; GSM1374652 GEO; GSM1401658 GEO; GSM1613823 GEO; GSM1670080 GEO; GSM1833624 GEO; GSM2095710 GEO; GSM2095711 GEO; GSM2124643 IARC_TP53; 6 IBRC; C10684 ICLC; HTL99004 IZSLER; BS TCL 223 KCB; KCB 200776YJ KCLB; 30026 LiGeA; CCLE_752 LINCS_HMS; 50058 LINCS_LDP; LCL-1461 Lonza; 815 MetaboLights; MTBLS337 MetaboLights; MTBLS387 NCBI_Iran; C578 NCI-DTP; MDA-MB-231 PRIDE; PXD000239 PRIDE; PXD000397 PRIDE; PXD000691 PRIDE; PXD000914 PRIDE; PXD001553 PRIDE; PXD002192 PRIDE; PXD002649 PRIDE; PXD005292 PRIDE; PXD005942 PRIDE; PXD010634 SKY/M-FISH/CGH; 2815 TOKU-E; 2394 Wikidata; Q17577870 DT Created: 04-04-12; Last updated: 05-07-19; Version: 31

Hierarchy

DT Created: 04-04-12; Last updated: 05-07-19; Version: 31

Originate from Same Individual

DT Created: 04-04-12; Last updated: 05-07-19; Version: 31