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Homo sapiens


Group: Space-flown cell line (cellonaut). Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Part of: ENCODE project common cell types; tier 2. Part of: JFCR39 cancer cell line panel. Part of: JFCR45 cancer cell line panel. Part of: ICBP43 breast cancer cell line panel. Part of: KuDOS 95 cell line panel. Part of: MD Anderson Cell Lines Project. Part of: NCI-60 cancer cell line panel. Registration: Chiron Master Culture Collection; CMCC 10377 (CMCC #10377). Doubling time: 1.8 days (PubMed=9671407); 80 hours (PubMed=25984343); 31.2 hours (PubMed=22628656); 25.4 hours (NCI-DTP); ~50 hours, with a range of 30-72 hours (DSMZ); ~38 hours (PBCF). HLA typing: A*02:01:01; B*18,44; C*05; DPB1*02:01:02,04:01; DQB1*02:01,06:02; DRB1*03,15 (PubMed=15748285). HLA typing: A*02:01,02:01; B*18:01,44:02; C*05:01,05:01; DQA1*01:02,01:02; DQB1*06:02,06:02; DRB1*15:01,15:01 (PubMed=25960936). Microsatellite instability: Stable (MSS) (PubMed=12661003; PubMed=23671654; Sanger). Sequence variation: Homozygous for CDKN2A deletion (PubMed=19593635). Sequence variation: Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (PubMed=17088437; PubMed=19593635; PubMed=28889351). Sequence variation: Has no TP53 mutation (PubMed=15900046). Omics: Array-based CGH. Omics: CNV analysis. Omics: Deep antibody staining analysis. Omics: Deep exome analysis. Omics: Deep phosphoproteome analysis. Omics: Deep proteome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: Fluorescence phenotype profiling. Omics: Glycoproteome analysis by proteomics. Omics: H3K27ac ChIP-seq epigenome analysis. Omics: H3K27me3 ChIP-seq epigenome analysis. Omics: H3K36me3 ChIP-seq epigenome analysis. Omics: H3K4me3 ChIP-seq epigenome analysis. Omics: H3K9me3 ChIP-seq epigenome analysis. Omics: lncRNA expression profiling. Omics: Metabolome analysis. Omics: miRNA expression profiling. Omics: Myristoylated proteins analysis by proteomics. Omics: N-glycan profiling. Omics: Protein expression by reverse-phase protein arrays. Omics: shRNA library screening. Omics: SNP array analysis. Omics: Transcriptome analysis. Omics: Virome analysis using proteomics. Genome ancestry: African=0.74%; Native American=0%; East Asian, North=4.2%; East Asian, South=0%; South Asian=0%; European, North=56.91%; European, South=38.15% (PubMed=30894373). Anecdotal: This is the first hormone-responsive breast cancer cell line to have been established. Anecdotal: Helen Mallon (sister Catherine Frances), the patient from which this cell line is derived was a nun (Sister Catherine Frances) at the Immaculate Heart of Mary Convent in Monroe, Michigan. Anecdotal: Have been flown in space on Foton-12 to study cytoskeleton architecture in microgravity (PubMed=11292682; PubMed=15002416). Misspelling: MFC-7; Occasionally. Discontinued: ATCC; CRL-12584. Discontinued: JCRB; NIHS0200. Derived from metastatic site: Pleural effusion. DT Created: 04-04-12; Last updated: 05-07-19; Version: 31

Proper Citation

CLS Cat# 300273/p2720_MCF-7, RRID:CVCL_0031


Cancer cell line DT Created: 04-04-12; Last updated: 05-07-19; Version: 31


DT Created: 04-04-12; Last updated: 05-07-19; Version: 31


MCF 7, MCF.7, MCF7, Michigan Cancer Foundation-7, ssMCF-7, ssMCF7, MCF7/WT, IBMF-7, MCF7-CTRL DT Created: 04-04-12, Last updated: 05-07-19, Version: 31



Cat Num


Cross References

BTO; BTO:0000093 CLO; CLO_0007601 CLO; CLO_0007605 CLO; CLO_0007606 CLO; CLO_0050868 EFO; EFO_0001203 MCCL; MCC:0000307 CLDB; cl3366 CLDB; cl3367 CLDB; cl3368 CLDB; cl3369 CLDB; cl3370 CLDB; cl3371 CLDB; cl3372 CLDB; cl3373 CLDB; cl3375 AddexBio; C0006008/402 ArrayExpress; E-MTAB-2706 ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 ArrayExpress; E-TABM-157 ArrayExpress; E-TABM-244 ATCC; CRL-12584 ATCC; HTB-22 BCRC; 60436 BCRJ; 0162 BioSample; SAMN01821575 BioSample; SAMN01821646 BioSample; SAMN01821698 BioSample; SAMN03473276 BioSample; SAMN05292458 BioSample; SAMN10988179 CCLE; MCF7_BREAST CCRID; 3111C0001CCC000013 CCRID; 3111C0001CCC000328 CCRID; 3131C0001000700074 CCRID; 3142C0001000000054 CCTCC; GDC0055 Cell_Model_Passport; SIDM00148 ChEMBL-Cells; CHEMBL3308403 ChEMBL-Targets; CHEMBL387 CLS; 300273/p2720_MCF-7 Cosmic; 687490 Cosmic; 755293 Cosmic; 809239 Cosmic; 871143 Cosmic; 875876 Cosmic; 877449 Cosmic; 894096 Cosmic; 897419 Cosmic; 904373 Cosmic; 905946 Cosmic; 912001 Cosmic; 921976 Cosmic; 923059 Cosmic; 934534 Cosmic; 944293 Cosmic; 947352 Cosmic; 949189 Cosmic; 970089 Cosmic; 979723 Cosmic; 991328 Cosmic; 997916 Cosmic; 1000123 Cosmic; 1010932 Cosmic; 1017161 Cosmic; 1018463 Cosmic; 1019310 Cosmic; 1046936 Cosmic; 1047712 Cosmic; 1066224 Cosmic; 1071901 Cosmic; 1092612 Cosmic; 1102382 Cosmic; 1136341 Cosmic; 1152527 Cosmic; 1175832 Cosmic; 1176603 Cosmic; 1176648 Cosmic; 1183770 Cosmic; 1287893 Cosmic; 1289391 Cosmic; 1305382 Cosmic; 1308991 Cosmic; 1312369 Cosmic; 1326278 Cosmic; 1434950 Cosmic; 1436031 Cosmic; 1477426 Cosmic; 1481420 Cosmic; 1523770 Cosmic; 1524349 Cosmic; 1571788 Cosmic; 1603215 Cosmic; 1609459 Cosmic; 1945860 Cosmic; 1995500 Cosmic; 1998454 Cosmic; 2162161 Cosmic; 2165024 Cosmic; 2301233 Cosmic; 2301526 Cosmic; 2307194 Cosmic; 2318370 Cosmic; 2361358 Cosmic; 2525755 Cosmic; 2553502 Cosmic; 2560248 Cosmic; 2668278 Cosmic-CLP; 905946 DepMap; ACH-000019 DSMZ; ACC-115 ECACC; 86012803 ENCODE; ENCBS000AAA ENCODE; ENCBS001AAA ENCODE; ENCBS017ENC ENCODE; ENCBS034XKZ ENCODE; ENCBS036ENC ENCODE; ENCBS037ENC ENCODE; ENCBS050QMU ENCODE; ENCBS053YJT ENCODE; ENCBS056AAA ENCODE; ENCBS094ENC ENCODE; ENCBS095ENC ENCODE; ENCBS096ENC ENCODE; ENCBS097ENC ENCODE; ENCBS098ENC ENCODE; ENCBS102ENC ENCODE; ENCBS103ENC ENCODE; ENCBS104ENC ENCODE; ENCBS105ENC ENCODE; ENCBS108ENC ENCODE; ENCBS123ZGI ENCODE; ENCBS134PJO ENCODE; ENCBS135SOE ENCODE; ENCBS143XXF ENCODE; ENCBS155VQC ENCODE; ENCBS158RRU ENCODE; ENCBS168ISE ENCODE; ENCBS174OTK ENCODE; ENCBS200IWR ENCODE; ENCBS216AOQ ENCODE; ENCBS236AAA ENCODE; ENCBS237AAA ENCODE; ENCBS240AAA ENCODE; ENCBS241AAA ENCODE; ENCBS242AAA ENCODE; ENCBS243AAA ENCODE; ENCBS244AAA ENCODE; ENCBS245AAA ENCODE; ENCBS246AAA ENCODE; ENCBS247AAA ENCODE; ENCBS248AAA ENCODE; ENCBS249AAA ENCODE; ENCBS250AAA ENCODE; ENCBS251AAA ENCODE; ENCBS252AAA ENCODE; ENCBS254AYH ENCODE; ENCBS267CRP ENCODE; ENCBS308QKF ENCODE; ENCBS325VCY ENCODE; ENCBS328UKJ ENCODE; ENCBS331EJR ENCODE; ENCBS488MMM ENCODE; ENCBS496HCC ENCODE; ENCBS530DHL ENCODE; ENCBS536NWC ENCODE; ENCBS546VBU ENCODE; ENCBS547AXB ENCODE; ENCBS564FRY ENCODE; ENCBS567IJO ENCODE; ENCBS581MUA ENCODE; ENCBS584TFV ENCODE; ENCBS609QTY ENCODE; ENCBS614ENC ENCODE; ENCBS615ENC ENCODE; ENCBS616ENC ENCODE; ENCBS616MBU ENCODE; ENCBS661RDG ENCODE; ENCBS670IYV ENCODE; ENCBS705BBA ENCODE; ENCBS747ZRJ ENCODE; ENCBS748WRO ENCODE; ENCBS789UPK ENCODE; ENCBS866ZXX ENCODE; ENCBS867ORK ENCODE; ENCBS873NNF ENCODE; ENCBS912WOF ENCODE; ENCBS957OEW ENCODE; ENCBS959SHH ENCODE; ENCBS967MVZ ENCODE; ENCBS974BZV GDSC; 905946 GEO; GSM1723 GEO; GSM2111 GEO; GSM2137 GEO; GSM2153 GEO; GSM50183 GEO; GSM50247 GEO; GSM69199 GEO; GSM73693 GEO; GSM115111 GEO; GSM155207 GEO; GSM156025 GEO; GSM185091 GEO; GSM185092 GEO; GSM211175 GEO; GSM274640 GEO; GSM276773 GEO; GSM276774 GEO; GSM276775 GEO; GSM276776 GEO; GSM276777 GEO; GSM276778 GEO; GSM276779 GEO; GSM320172 GEO; GSM344347 GEO; GSM344397 GEO; GSM350552 GEO; GSM378140 GEO; GSM388212 GEO; GSM421869 GEO; GSM459726 GEO; GSM472936 GEO; GSM481303 GEO; GSM510510 GEO; GSM533396 GEO; GSM533413 GEO; GSM590108 GEO; GSM679692 GEO; GSM679693 GEO; GSM679694 GEO; GSM736581 GEO; GSM736588 GEO; GSM739996 GEO; GSM739997 GEO; GSM739998 GEO; GSM750771 GEO; GSM750777 GEO; GSM750778 GEO; GSM750801 GEO; GSM783949 GEO; GSM799320 GEO; GSM799383 GEO; GSM816438 GEO; GSM816627 GEO; GSM816670 GEO; GSM822295 GEO; GSM822305 GEO; GSM825711 GEO; GSM827593 GEO; GSM847394 GEO; GSM847490 GEO; GSM844586 GEO; GSM844587 GEO; GSM887291 GEO; GSM888366 GEO; GSM923442 GEO; GSM935445 GEO; GSM935477 GEO; GSM935563 GEO; GSM945269 GEO; GSM945274 GEO; GSM945854 GEO; GSM945857 GEO; GSM967819 GEO; GSM967823 GEO; GSM970217 GEO; GSM970218 GEO; GSM987741 GEO; GSM987742 GEO; GSM987743 GEO; GSM1008565 GEO; GSM1008581 GEO; GSM1008603 GEO; GSM1008904 GEO; GSM1010734 GEO; GSM1010764 GEO; GSM1010768 GEO; GSM1010769 GEO; GSM1010783 GEO; GSM1010791 GEO; GSM1010800 GEO; GSM1010811 GEO; GSM1010825 GEO; GSM1010837 GEO; GSM1010838 GEO; GSM1010839 GEO; GSM1010844 GEO; GSM1010860 GEO; GSM1010861 GEO; GSM1010862 GEO; GSM1010863 GEO; GSM1010864 GEO; GSM1010889 GEO; GSM1010891 GEO; GSM1010892 GEO; GSM1022658 GEO; GSM1022663 GEO; GSM1029440 GEO; GSM1029441 GEO; GSM1029442 GEO; GSM1029443 GEO; GSM1029444 GEO; GSM1029445 GEO; GSM1029446 GEO; GSM1029447 GEO; GSM1029448 GEO; GSM1029449 GEO; GSM1040306 GEO; GSM1040376 GEO; GSM1053687 GEO; GSM1068138 GEO; GSM1068139 GEO; GSM1153389 GEO; GSM1172885 GEO; GSM1181258 GEO; GSM1181263 GEO; GSM1214589 GEO; GSM1238132 GEO; GSM1374643 GEO; GSM1374644 GEO; GSM1374645 GEO; GSM1401653 GEO; GSM1670076 GEO; GSM1833626 GEO; GSM2046560 GEO; GSM2046561 GEO; GSM2046562 GEO; GSM2046563 GEO; GSM2046564 GEO; GSM2046565 GEO; GSM2046566 GEO; GSM2046567 GEO; GSM2046568 GEO; GSM2046569 GEO; GSM2046570 GEO; GSM2046571 GEO; GSM2046572 GEO; GSM2046573 GEO; GSM2046574 GEO; GSM2046575 GEO; GSM2046576 GEO; GSM2046577 GEO; GSM2046578 GEO; GSM2046579 GEO; GSM2046580 GEO; GSM2046581 GEO; GSM2046582 GEO; GSM2046583 GEO; GSM2046584 GEO; GSM2046585 GEO; GSM2046586 GEO; GSM2046587 GEO; GSM2046588 GEO; GSM2046589 GEO; GSM2046590 GEO; GSM2046591 GEO; GSM2046592 GEO; GSM2046593 GEO; GSM2046594 GEO; GSM2046595 GEO; GSM2046596 GEO; GSM2046597 GEO; GSM2046598 GEO; GSM2046599 GEO; GSM2046600 GEO; GSM2046601 GEO; GSM2046602 GEO; GSM2046603 GEO; GSM2046604 GEO; GSM2046605 GEO; GSM2046606 GEO; GSM2046607 GEO; GSM2095708 GEO; GSM2095709 GEO; GSM2124642 GEO; GSM2136630 GEO; GSM2136631 GEO; GSM2136632 GEO; GSM2136633 GEO; GSM2136634 GEO; GSM2136635 GEO; GSM2176269 GEO; GSM2176270 IARC_TP53; 21079 IBRC; C10082 IBRC; C10682 ICLC; HTL95021 IGRhCellID; MCF7 IPD-IMGT/HLA; 12401 IZSLER; BS TCL 38 JCRB; JCRB0134 JCRB; NIHS0200 KCB; KCB 200831YJ KCLB; 30022 LiGeA; CCLE_648 LINCS_HMS; 50029 LINCS_LDP; LCL-1460 Lonza; 113 MeSH; D061986 MetaboLights; MTBLS177 MetaboLights; MTBLS182 MetaboLights; MTBLS241 MetaboLights; MTBLS337 MetaboLights; MTBLS430 NCBI_Iran; C135 NCI-DTP; MCF7 PRIDE; PXD000275 PRIDE; PXD000281 PRIDE; PXD000309 PRIDE; PXD000442 PRIDE; PXD000623 PRIDE; PXD000691 PRIDE; PXD001274 PRIDE; PXD001352 PRIDE; PXD001812 PRIDE; PXD001863 PRIDE; PXD002104 PRIDE; PXD002192 PRIDE; PXD002395 PRIDE; PXD002421 PRIDE; PXD002998 PRIDE; PXD003704 PRIDE; PXD004051 PRIDE; PXD004085 PRIDE; PXD004357 PRIDE; PXD005032 PRIDE; PXD005390 PRIDE; PXD005940 PRIDE; PXD005942 RCB; RCB1904 SKY/M-FISH/CGH; 2814 TKG; TKG 0479 TOKU-E; 2383 TOKU-E; 3748 Wikidata; Q1881253 DT Created: 04-04-12; Last updated: 05-07-19; Version: 31


DT Created: 04-04-12; Last updated: 05-07-19; Version: 31

Originate from Same Individual

DT Created: 04-04-12; Last updated: 05-07-19; Version: 31