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Genolevures: Genomic Exploration of the Hemiascomycete Yeasts (RRID:SCR_013203)Copy Citation Copied
URL: http://cbi.labri.fr/Genolevures/
Proper Citation: Genolevures: Genomic Exploration of the Hemiascomycete Yeasts (RRID:SCR_013203)
Description: Gnolevures provides annotated sequence data and classifications for the genomes of eighteen species of hemiascomycete yeasts, including nine complete genomes. The Gnolevures web resources provides genetic element pages, orthologs defined by syntenic homology, protein families, a genome browser for interspecies comparison, and data sets for downloading. It also provides exploratory tools and curated data sets relative to nine complete and seven partial genome sequences determined and manually annotated by the Gnolevures Consortium, to facilitate comparative genomic studies of Hemiascomycete yeasts. The 2008 update to the Gnolevures database provides four new genomes in complete (subtelomere to subtelomere) chromosome sequences, 50 000 protein-coding and tRNA genes, and in silico analyses for each gene element. A key element is a novel classification of conserved multi-species protein families and their use in detecting synteny, gene fusions and other aspects of genome remodeling in evolution. The purpose is to release high-quality curated data from complete genomes, with a focus on the relations between genes, genomes and proteins. It is a large-scale comparative genomics project between Saccharomyces cerevisiae and other yeast species representative of the various branches of the Hemiascomycetous class. They sequence and manually curate both complete genomes and random genomic libraries. It addresses basic questions concerning molecular evolution: species-specific and class-specific genes, distribution of genes among functional families, rate of divergence, mechanisms of chromosome shuffling. With their relative small genome size, yeasts offer a unique opportunity for exploring eukaryotic genome evolution by comparative analysis of several species. Sponsors: French National center for Scientific Research (CNRS) (GDR 2354, partial); French National Research Agency (ANR) (ANR-05-BLAN-0331; GENARISE, partial); Rgion Aquitaine (Ple de Recherche en Informatique) (2005-1306001AB, partial) and ACI IMPBIO (IMPB114, partial) (Gnolevures En Ligne). Funding for open access charge: CNRS GDR 2354.
Synonyms: Genolevures
Resource Type: data or information resource, database
Keywords: element, evolution, family, fungal genome databases, fusion, genetic, chromosome, classification, coding, comparison, genome, genomic, hemiascomycete, homology, interspecies, mechanism, ortholog, protein, saccharomyces cerevisiae, sequence, size, specie, subtelomere, trna, yeast
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Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
