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Laboratory Support supplies support services for laboratory-based programs at the University of Hawai?i Cancer Center. This resource is operated in order to streamline and make more centralized common laboratory needs.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented January 24, 2019. Core aims to promote multidisciplinary collaboration, and enhance the research excellence and productivity of CRCH by providing access to biomedical informatics expertise and computational support to all members of the Center. The prime objective of the ISR is to facilitate the management, sharing, and integration of diverse data types in cancer research, as well as the synthesis and analysis of more focused data sets from the basic, clinical, genomics and population sciences. The bioinformatics group of the ISR supports a dedicated scientific computing network for computational cancer biology, and leads the development and application of advanced algorithms and software tools that enable Center investigators to take a more integrative approach to cancer research for the purpose of accelerating the translation of basic research results into the clinic.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core to provide bioinformatics analysis and consulting service, to increase the research capacity in bioinformatics in the State of Hawaii, to provides software applications, hardware, access, and support to researchers who utilize genomic and proteomic data. Undertake collaborative project with INBRE researchers to develop novel tools or applications that address specific needs. Develop an academic program in bioinformatics with the John A. Burns School of Medicine (JABSOM). Recruit a full-time junior faculty member to lead the academic program. Conduct training workshops and courses, and run a user support help desk.

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• SciCrunch
• 13 years ago - by Anonymous

HSFL was established in May 2007 within the School of Ocean and Earth Science and Technology (SOEST) and the College of Engineering (CoE) at the University of Hawaii. As a multidisciplinary research and education center HSFL brings together individuals from diverse areas to work on the exploration and understanding of the space environment. The mission of HSFL is to: * Promote innovative engineering and science research for terrestrial and planetary space missions. * Develop, launch, and operate small spacecraft from the Hawaiian Islands to accelerate the validation of new space technologies. * Provide workforce training in all aspects of unmanned space missions. * Build synergistic collaborations among educational, governmental, and corporate institutions interested in space exploration. Hawaii is located in a unique position to become a low-cost gateway to space and to place the University of Hawaii as the only university in the world to have both satellite fabrication capabilities and unique, direct access to orbital space. This will enable diverse missions that study Earth''s oceans and continents from low-Earth orbit, as well as the testing of engineering experiments in the hostile environment of space.

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• SciCrunch
• 13 years ago - by Anonymous

HURL''s facilities include two deep-diving (2000 m) submersibles Pisces V and Pisces IV, a remotely operated vehicle RCV-150, and the support ship R/V Ka''imikai-o-Kanaloa. The two submersibles are housed and maintained at Makai Pier. HURL Data Archive: HURL provides a data package for each Pisces IV, Pisces V or RCV-150 dive. This package includes voice transcripts (Pisces IV & V only), graphs of environmental data (Pisces IV & V only), copies of videotapes with videologs, and copies of up to 250 slides with a photolog. The Data Archive is the custodian of the original data which remain the property of HURL. Databases of organisms and substrates observed on the dives are available for use by the principal investigator. Use of dive data by other scientists is subject to principal investigator approval for 2 years. HURL and NOAA-NURP reserve the right to use slides and video from dives for program promotion.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 17,2026. Core facility that provides the following services: DNA and RNA quantification service, DNA quality analysis service, RNA quality analysis service, Genotyping service, Gene expression analysis and DNA copy number analysis service, Pyrosequencing service. The purpose of the Genomics Shared Resource (GSR) laboratory is to provide expertise in the fast developing area of genomic analysis. In response to a growing need for genotyping services by a number of UH Cancer Center investigators, this laboratory was converted into a UH Cancer Center Shared Resource in 1999. Its current mission is to provide nucleic acid extraction, genotyping and expression profiling services in support of the peer-reviewed and IRB-approved research conducted by UH Cancer Center members.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 17, 2026. The Evolutionary Genetics Core Facility (EGCF) at the Hawaii Institute of Marine Biology (HIMB) is located on Coconut Island in Kaneohe Bay, Oahu. The NSF EPSCoR-supported Core Facility provides technical services and support for the faculty and students doing research at HIMB and the University of Hawaii system, as well as other institutions worldwide. The EGCF provides access to various instrumentation and equipment and offers fee-based genomic services including sequence and fragment analysis. The EGCF manager is available to provide services and assist with questions regarding lab instrumentation or protocols.

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• SciCrunch
• 13 years ago - by Anonymous

The Clinical Protocol and Data Management Shared Resource (CPDM) is a component of the Center?s Clinical Trials Unit that provides central management and oversight of all clinical trials activities of the Center. The Shared Resource provides a range of management and quality control functions that are essential for conducting clinical trials research in Hawaii?s decentralized community practice setting. It includes a central location for all cancer protocols, a centralized database of protocol-specific data, an updated list of currently active protocols for the use of Center investigators, and status reports of protocols. It provides a centralized organization for activating and monitoring protocols throughout Hawaii?s multiple community offices and medical centers involving several Institutional Review Boards (IRBs). Quality control functions include: insuring subject safety and compliance with federal requirements through the Data and Safety Monitoring plan, insuring staff competency through training for research nurses, CRAs, clinical trials assistants and community office, clinic, and hospital staff engaged in Hawaii?s cancer clinical trials enterprise, and insuring recruitment of underserved minorities through focused outreach activities.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Transgenic mouse generation, In vitro fertilization (IVF) service, Embryo culture service, Embryo freezing service. The Transgenic and Embryonic Stem Cell Gene Targeting Core is a state-of-the-art facility with the expertise in the production of genetically altered subjects. Transgenic subjects carrying new or novel genes are created by microinjection of DNA into the pronuclei of fertilized eggs. Knock-out lacking specific genes of interest are created by homologous recombination in embryonic stem cells followed by injection into blastocysts to create chimeric subjects. Highly experienced personnel produce transgenic and knock-out subjects for UH investigators at very reasonable cost and with very short lead times. (http://www.ibr.hawaii.edu/tc.html)

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Aortic banding service, Echocardiogram service, Blood pressure measurement service, Osmotic pump implantation service, LAD ligation service, Mini pump insertion service, Isolated perfused heart assay service, Cryoablation service, Cardiac output measurement service, Small animal surgery service, Transverse aortic constriction service, Invasive hemodynamic measurement service, Tail vein injection service, Training and advice for general mouse surgery techniques. The Center for Cardiovascular Research provides a Mouse Phenotyping Core for the use of investigators at the University, and by special arrangement, for investigators anywhere in Hawaii. We can provide murine echocardiography, blood pressure determinations, surgical procedures and phlebotomy, as well as assistance with mouse husbandry and genotyping.(http://www2.jabsom.hawaii.edu/mousecore/)

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Fluorescent microscopy consultation service.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Real-time/quantitative PCR service, Long read (900bp) sequencing service, Microarray sample labeling service, Automated liquid handling service, DNA/RNA sample concentration service, Spectrophotometry service, Microarray scanning service. Offers services in the areas of qPCR, Microarray, Sequencing, and Other Genomic Services. May expand or remove services depending on need or interest. If you have recurring processes that you would like to automate or have us take over, we would be glad to sit down and talk with you to discuss how we can help you acheive your goals. We are aiming to be a self-sustaining entity consisting solely on a chargeback system. Our prices reflect the costs of equipment service contracts, potential and actual maintenence costs, as well as direct and indirect labor costs and administration. Our costs are kept low by being able to provide services in bulk with high throughput, it is therefore sometimes necessary to have minimum orders or fees in order to maintain a positive cost structure.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core provides access to high speed computer hardware and bioinformatics consultation. Research at the facility includes studying of evolutionary change in emergent dengue viruses associated with increasingly severe epidemics and confirm the impact of these changes in experimental models.

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• SciCrunch
• 13 years ago - by Anonymous

The Biostatistics Shared Resource (BSR) provides statistical consultation and support to the research enterprise of the University of Hawai?i Cancer Center. The primary goal of the resource is to improve the quality of the research through sound statistical principles. The resource was established in 1995 and provides access to statistical support to all Center members on all aspects of research. The BSR provides short-term as well as long-term support for research projects. Support is provided to scientists in epidemiology, health behavior and quality of life research, and molecular and clinical oncology. The members of the Shared Resource often serve as co-investigators on epidemiology and cancer prevention and control projects. Consultation is available in the following areas: design, data collection, data analysis, statistical programming, interpretation and dissemination of results, and protocol review. The members of the resource have contributed to the publication of many peer-reviewed manuscripts from Center research projects. In addition, the statisticians work on methodological issues important to the research ongoing at UH Cancer Center. One area of interest is measurement error models that correct for bias in model parameter estimates when the exposure variable is measured with error. The role of dietary intake and sunlight exposure in cancer etiology are of interest at the Center, and these variables are measured with error. Another interest is in how susceptibility genes affect cancer risk, in combination with exposure data. Therefore, statistical techniques for the investigation of genes and lifestyle-gene interactions in cancer models are also studied.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Scanning electron microscopy service, Conventional and energy-filtering transmission electron microscopy service, Laser scanning confocal microscopy service, Fluorescence microscopy service, Laser microdissection and laser tweezing service. The Biological Electron Microscope Facility (BEMF) at the University of Hawai''i is a multi-user/service facility, administered by the Pacific Biosciences Research Center (PBRC). The mission of the BEMF is to provide biological-biomedical researchers with state-of-the-art instrumentation, training and services for high-resolution scanning electron microscopy, conventional and energy-filtering transmission electron microscopy, optical, fluorescence, and laser scanning confocal microscopy, and image analysis on a recharge basis. The facility receives partial support from the Pacific Biosciences Research Center and the UH Manoa Chancellor''s Office. Includes the Richard Allen Image Collection, a unique set of images taken with electron microscopes (http://www5.pbrc.hawaii.edu/allen/).

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 17,2026. A 2000 square foot BSL-3 facility located at the University of Hawaii, JABSOM.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: ELISA-based assay service, Luminex based ELISA assay service, Coenzyme Q10 in plasma analysis by HPLC/ECD (oxidized, reduced and total Q10), DNA analysis by HPLC, Phenolic agents from plasma, urine, breast milk, foods analysis by LC/MSMS, Lipid-phase micronutrients in plasma or foods analysis by HPLC/PDA/FD (12 carotenoids, 2 retinoids, 3 tocopherols), Metabolomics analysis by LCMS, Vitamin A and pro-vitamin A in plasma analysis by HPLC/PDA, Vitamin C in plasma, food analysis by HPLC/ECD or PDA, Vitamin D in plasma analysis by LC/MSMS, Vitamin E in plasma analysis by NP-HPLC/PDA/FD (all tocopherols), Vitamin K analysis by LC/MSMS. The Analytical Biochemistry resource was established to support and facilitate collaborative cancer research between the various disciplines at the Center by providing chemical analyses which contribute to understanding chronic diseases in our population. It also assists in the determination of the nature or structure of biological molecules as well as the quantification of those compounds. The facility is equipped with essential instruments needed to perform analytical chemistry, and modern, state-of-the-art technology for difficult-to-measure and ultra-low concentrated compounds.

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• SciCrunch
• 13 years ago - by Anonymous

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• SciCrunch
• 14 years ago - submitted by Andrea Stagg

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 17,2026. Core facility that provides the following services: MRI image analysis service, MRI image processing service.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Solid state studies service.

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• SciCrunch
• 13 years ago - by Anonymous