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Genetic Alliance Registry and BioBank is a centralized, clinical data registry and sample repository (including DNA, serum, cells and tissues) that enables translational research. It is a nonprofit organization established by seven patient advocacy organizations. These organizations share resources for their BioBanks, such as the contract to the independent lab that processes the samples, but each organization will maintain ownership, control and costs associated with their sample collection. Founded in 2003, this cooperative venture provides shared infrastructure and customized solutions for disease advocacy organizations to lead sophisticated research initiatives. Genetic Alliance Registry and BioBank is an advocacy owned repository for biological samples and clinical data. It provides: * Centralized, standardized collection and archiving * Highest biorepository and participant protection standards * Open access for all organization approved researchers * Advocacy organization control

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• SciCrunch
• 16 years ago - by Anonymous

RUCDR is a biobank and a service organization that maintains human blood, serum, saliva, tissue and the genetic products derived from those. Services include technical consultation and logistical support for biobanking. Researchers can order biomaterials and apply for phenotypic / genotypic data.

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• SciCrunch
• 16 years ago - by Anonymous

The Molecular Modeling DataBase (MMDB), also known as Entrez Structure, is a database of experimentally determined structures obtained from the RCSB Protein Data Bank (PDB). MMDB is developed by the Structure Group of the NCBI Computational Biology Branch. The data processing procedure at NCBI results in the addition of a number of useful features that facilitate computation on the data and link them to many other data types in the Entrez system. The structure database is considerably smaller than Entrez''s Protein or Nucleotide databases, but a large fraction of all known protein sequences have homologs in this set, and one may often learn more about a protein by examining 3-D structures of its homologs. These are accessible as Related Structures in the Links menu of Entrez Protein sequence records (illustrated example). It is then possible to align the query protein to the structure-based sequence, as shown in the illustration on this page. Additional resources can be used along with MMDB to interactively view the structures, find similar 3D structures, learn about the types of interactions and bound chemicals that have been found to exist among the similar 3D structures, and more.

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• SciCrunch
• 16 years ago - by Anonymous

BioBancUSA is a leading biotechnology company specializing in white blood cell collection, processing, cryopreservation and storage service. BioBancUSA, a private company headquartered in Monterey, California, is the exclusive licensee of the original patent for the collection, processing and cryopreservation technology of white blood cells, giving you the assurance of both technical integrity and legal legitimacy that you can count on. BioBancUSA is dedicated to providing our clients with the highest quality immune cell preservation for their future medical use. We are committed to the most advanced technology, exceptional, personalized service and leading-edge innovation to benefit our customers, health care providers, shareholders and employees.

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• SciCrunch
• 16 years ago - by Anonymous

Project to develop tools that explore single neuron function via sophisticated image analysis. ORION software bridges advanced optical imaging and compartmental modeling of neuronal function by rapidly, accurately, and robustly generating, from structural image data, a cylindrical morphology model suitable for simulating neuronal function.

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• SciCrunch
• 16 years ago - by Anonymous

Access service resource which connects labs needing and offering experimental services. Users can search for academic and government labs and experimental services, request and compare service quotes, and directly communicate with labs to arrange orders.

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• SciCrunch
• 16 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented on October 6, 2011. A project to collect, store and study DNA samples from tens of thousands of healthy volunteers and patients with diseases of major public importance. It aims to identify genes that are risk factors for the conditions. The network consists of 13 collections led by different clinicians throughout the UK. At its heart is an archive infrastructure which manages the DNA and the information associated with it. The European Collection of Cell Cultures in Porton Down handles the blood, peripheral blood lymphocytes and EBV-transformed cell lines, while the Centre for Integrated Genomic Medical Research at Manchester University manages the DNA. These banked samples are available to UK and international researchers, who can examine data and set up collaborative work by registering at the DNA Network's website. The conditions for which samples are currently collected and stored are: Acute leukemia, Asthma and eczema, Late onset Alzheimer's disease, Breast cancer, Colorectal cancer, Coronary artery disease, Glomerulonephritis, Hypertension, Age-related macular degeneration, Multiple sclerosis, Parkinson's disease, Type 2 diabetes, Unipolar depression.

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• SciCrunch
• 16 years ago - by Anonymous

Families of Spinal Muscular Atrophy is dedicated to creating a treatment and cure by: - Funding and advancing a comprehensive research program; - Supporting SMA families through networking, information and services; - Improving care for all SMA patients; - Educating health professionals and the public about SMA; - Enlisting government support for SMA; - Embracing all touched by SMA in a caring community. Our vision is a world where Spinal Muscular Atrophy is treatable and curable.

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• SciCrunch
• 16 years ago - by Anonymous

A cell culture collection to service the research community and provide an International Depository Authority recognized patent depository for Europe. The collections currently hold over 40,000 cell lines representing 45 different species, 50 tissue types, 300 HLA types, 450 monoclonal antibodies and at least 800 genetic disorders. ECACC has developed a comprehensive range of cell culture services and diversified into new product areas such as high quality genomic DNA extracted from cell lines. ECACC is one of the four collections which constitute the Health Protection Agency Culture Collections (HPA Culture Collections). Its products include: General Cell Collection, Hybridoma Collection, Primary Cells, Neuron Culture Kits, HepaRG Cells, GPCR Cell Lines, HLA-Typed Collection, Human Random Control Collection, Human Genetic Collection, and DNA Products. Its services include: Assay Ready Cells, Cell Culture Management Services, Contract Cell Culture, Cell Line Identity Verification, Genetic Support Services, Mycoplasma Testing and Eradication, Patent Deposits, Safe Deposits, Sterility Testing, and Training.

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• SciCrunch
• 16 years ago - by Anonymous

AutoCSA (Automatic Comparative Sequence Analysis) is a mutation detection program designed to detect small mutations (1-50 bases) in sequence traces. The software is capable of detecting both homozygous and heterozygous base substitutions, as well as small insertions and deletions, to a high sensitivity. It has specifically been written with high throughput environments in mind, so it is easy to automate the analysis of large amounts of data with little manual intervention. AutoCSA is written in java and will run under java 1.4 or later versions which must be downloaded and installed on your computer. It should be emphasised that AutoCSA uses the raw sequence channels from the trace files generated by the ABI sequencers (.ab1 file extension). Traces which have been processed and the raw channels removed are not suitable for use with the software. The software has been tested successfully under Linux, MS windows XP, and Mac OS X 10.

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• SciCrunch
• 16 years ago - by Anonymous

Not yet vetted by NIF curator

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• SciCrunch
• 16 years ago - by Anonymous

As both the public health survey of Quebec, and the Quebec resource for scientists interested in personalized medicine, genomics and public health, this public resource operates under a governance framework and consists of a databank and a biobank. The database contains environmental, demographic and health data. The biobank contains DNA, blood and urine samples. Access to CARTaGENE will be granted to researchers who are seeking to better understand how genes interact with other genes, with the environment and with lifestyle factors. They have collected in-depth information on over 20 000 Quebecers, including 446 sociodemographic, life-style and health data, 190 physiological parameters, 22 types of biochemical analyses and 41 types of haematological analyses. They have also collected 11 types of blood, plasma, serum and urine samples from most participants. Genealogical reconstruction of recruited participants, in collaboration with BALSAC Project, is also possible. CARTaGENE data and samples include the following: Health Questionnaire, Physical measures, Biochemical and hematological analysis, Biological samples stored in the Biobank. CARTagene is currently contacting participants (who have agreed to be recontacted) to collect additional data on environmental exposure. Data on dietary habits will be collected during the second phase of this component which will begin soon. Any scientific researcher working in a public or private organization at the national or international level may apply for access to CARTaGENE samples or data.

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• SciCrunch
• 16 years ago - by Anonymous

We developed this Web site for researchers, primary care physicians, caregivers, students and those with a general interest in Alzheimer's Disease. Utilizing the many resources and web links, we think you will find this a useful portal to understanding the many facets of Dementia. The center is part of nationwide and statewide programs. The ADC has several important goals: * Educate health professionals and the public about Alzheimer's disease and related dementias * Conduct research in clinical and community populations into the causes and potential treatments for dementia * Advocate changes in health policy and practice that will enhance the recognition, treatment and management of dementia * Serve as an expert referral center for the diagnosis of dementia

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• SciCrunch
• 16 years ago - by Anonymous

A software application for the de novo assembly of genomes from fragments of DNA that specifically attacks the question of scalability.

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• SciCrunch
• 13 years ago - by Anonymous

The University Memory and Aging Center (formerly known as University Alzheimer Center) is a partnership of Case Western Reserve University and University Hospitals of Cleveland promoting the best possible care for persons with memory problems, and assisting their families, through an integrated program of clinical services, research, and education. Our staff includes a wide range of professionals dedicating their time and efforts to understand and work for the betterment of those affected by any disorder which affects cognitive abilities. We include Neuroscientists, Neurologists, Psychologists, Sociologists, Social Workers, Nurses, Clinical trials coordinators, Research Assistants, Data Managers and Administrative staff. We work with researchers in Cleveland, throughout the US and around the globe.

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• SciCrunch
• 16 years ago - by Anonymous

Free medical app for comprising a drug reference, drug interaction checker, disease and condition reference, procedures and protocols and specialty-focused Medical News * Drug Reference: Search prescribing and safety information for over 8,000 brand, generic and OTC drugs, herbals and supplements * Drug Interaction Checker: Check mild interactions to serious contraindications for any combination of drugs, herbals and supplements * Disease & Condition Reference: Review the latest in-depth clinical information for 4,000+ diseases and conditions (enhanced with images and videos) *Procedures & Protocols: Follow detailed stepbystep instructions for 600+ clinical procedures, including 80+ widely used Tables & Protocols * Specialty-focused Medical News: Read in-depth medical news articles daily in 30 specialty areas

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• SciCrunch
• 16 years ago - by Anonymous

The Ontario Institute for Cancer Research (OICR) is a centre of excellence in cancer research with a focus on prevention, early detection, diagnosis and treatment of cancer. The Institute is an independent, not-for-profit corporation bringing together multi-disciplinary, multi-institutional collaborations, which will allow complex questions to be pursued. It is translating research findings into programs, technologies and therapies. Established in December, 2005, the Institute will support more than 50 internationally recognized principal investigators; there will be a strong core of scientists at the MaRS Centre with the remainder in nodes of excellence around the province. The Institute is leveraging the current research excellence at universities, research hospitals and health research institutes across Ontario, leading to greater integration of cancer research efforts across institutions. The Ontario Cancer Research Network, established in 2002, has been incorporated into the Institute. Its initiatives will continue under the umbrella of the Institute and will include: Cancer Research Fund, Clinical Trials Infrastructure Fund, Clinical Trials Network, OntarioCancerTrials.ca, Ontario Cancer Research Ethics Board, and Ontario Tumour Bank.

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• SciCrunch
• 16 years ago - by Anonymous

A collection of over 640,000 specimens of amphibians, reptiles, birds, bird eggs or nests, and mammals, as well as over 50,000 tissue samples from these vertebrate groups. These research collections are ranked as one of the largest in the United States, and the largest of any university museum. In addition, the Museum has numerous special collections that include archived field notes and photographs, historical annotated maps and correspondence, avian sound recordings, chromosome and histology preparations, Milton Hildebrand anatomical and film collections, artwork related to terrestrial vertebrate natural history, and a library of books, reprints, and journals for curation and research activities. Specimen data are accessible online, and the Museum is working to improve data access to the other collections. Museum Collections * Mammal Collection * Herpetological Collection * Bird Collection * Egg & Nest Collection * Tissue Collection * Fieldnotes, Photos, & Map Collection * Other Collections The Museum of Vertebrate Zoology (MVZ) welcomes donations of amphibians, reptiles, birds, bird eggs and nests, mammals and related materials. Acceptance of a donation is at the discretion of MVZ Curators. * Specimens -- May include preserved specimens and/or parts (e.g., tissue samples) as well as unpreserved material (e.g., frozen carcasses, live animals) that will be prepared by Museum Curators, curatorial staff, or students. * Related Materials -- Donations of images (digital or printed photographs or slides), sound recordings, field notes, and other natural history archival material. Materials must be connected to specimens or research projects. Donated material and associated data will be made available for research, education, or public exhibit according to the mission and policies of the Museum and Regents, except by prior signed agreement between the donor and the Museum.

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• SciCrunch
• 16 years ago - by Anonymous

NIA Aged Rodent Tissue Bank (ARTB) is a repository of tissue collected from mice and rats maintained in the NIA Aged Rodent Colonies. Biospecimens are collected, archived, and distributed under a contractual arrangement with the University of Washington, Seattle. The NIA supports the three R’s of research (Replacement, Reduction, and Refinement) through maximizing the use of existing banked samples from mice and rats and providing tissues for research on aging. Researchers can select frozen tissues, unstained slides from formalin-fixed and paraffin-embedded (FFPE) tissues, or tissue microarrays (TMAs).

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• SciCrunch
• 16 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVCE, documented September 6, 2016. This wiki focuses on the process, techniques and tools of high quality searching in the context of evidence-based health care. Information collected in the wiki is primarily intended for medical librarians, but may be of interest to others. Please keep in mind that search strategies and tools here are intended for use by trained professionals in the course of their professional duties, and are not intended for use by the general public. If they are helpful or useful to others that is a plus, but not the primary purpose of the site.

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• SciCrunch
• 16 years ago - by Anonymous