SciCrunch

MMPC-University of Cincinnati Medical Center Cardiovascular and Renal Function Core

Core that offers services in testing animal physiological variables such as blood pressure, heart rate, pulse pressure and activity after inserting a PA-C10 telemetry device in them.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

MMPC-University of California Davis Endocrinology and Metabolism Core

Core that provides phenotyping services for the assessment of endocrine function and metabolic pathways in mouse models of obesity, diabetes, and related metabolic diseases including dyslipidemia and fatty liver disease.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Mouse Metabolic Phenotyping Centers

Organization whose mission is to advance medical and biological research by providing the scientific community with standardized, high quality metabolic and physiologic phenotyping services for mouse models of diabetes, diabetic complications, obesity and related disorders.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

MMPC-University of California Davis

Center that provides the scientific community with metabolic and physiologic phenotyping tests, services, and procedures for mouse models of diabetes, diabetic complications, obesity and related disorders in order to advance medical and biological research.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

MMPC-University of California Davis Animal Care Surgery and Pathology Core

Core that provides importation/exportation, colony management, customized mouse models, rederivation and creation of genetically-modified mutant mice (e.g. CRISPR), and re-animation of a variety of models cryopreserved within the KOMP or MMRRC repositories. It also provides ancillary services and procedures, including blood sampling for in vivo testing for glucose tolerance tests and insulin tolerance tests.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Boston Children's Hospital Center of Excellence in Molecular Hematology Zebrafish Core

Zebrafish core facility which generates and maintains transgenic and mutant fish lines for hematology research. It also provides expertise and training in model production, study design, and fish production for research.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

MMPC-University of Michigan Medical School Metabolism Bariatric Surgery and Behavior Core

Core whose services include in vivo physiological assessments encompassing glucose homeostasis (glucose tolerance, insulin tolerance, hyperinsulinemic/euglycemic clamps), energy homeostasis (indirect calorimetry by CLAMS, dietary challenge), ultradian hormone secretion (Culex platform for serial biological fluid sampling from unrestrained mice), behavioral measurements (locomotor activity, meal pattern analysis, operant conditioning) and generation of bariatric surgery models.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

MMPC-Vanderbilt University School of Medicine Cardiovascular Pathophysiology Core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 6th,2023. Core whose objective is to provide investigators at Vanderbilt and outside institutions a means to accurately assess cardiovascular phenotypes in mouse models of diabetes and metabolic disease. The CPC uses validated approaches and state-of-the-art instrumentation that allow for sensitive screening of phenotypic variations.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Boston Children's Hospital Center of Excellence in Molecular Hematology Stem Cell Engineering and Analysis Core

Core facility for basic and translational stem cell research. The core's areas of expertise include human pluripotent stem cell biology, cGMP cell manufacturing, reprogramming, genome editing, genotyping, laboratory automation, chemical screening, and imaging/image analysis.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Yale Cooperative Center of Excellence in Hematology

Research center that provides access to and training in hematology technologies via three technology cores, Pilot and Feasibility funding, and an Enrichment Program.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Boston Children's Hospital Center of Excellence in Molecular Hematology Mouse Embryonic Stem(ES) Cell and Gene Targeting Core

Core facility which generates genetically modified mice with gene knockout/knockin lines for analysis gene function in hematopoiesis.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Yale Cooperative Center of Excellence in Hematology Animal Modeling Core

Core facility which provides expertise, technical assistance, and mice for human-into-mouse xenotransplantation studies. Mouse models include MITRG-SKI (KnockIn) mice that express human cytokines and huSIRPa from the endogenous murine loci in the Rag-/- IL-2Ry -/- background. It also offers training and technical assistance in the study of hematopoiesis and benign hematologic questions in mice.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Boston Children's Hospital Center of Excellence in Molecular Hematology

Research center investigating molecular hematology through mouse and zebrafish models.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Indiana University Cooperative Center of Excellence in Hematology Optical Microscopy Core

Core facility which provides access to and training on optical microscopy instruments to Indiana University researchers.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Indiana University School of Medicine Flow Cytometry Core Facility

Core facility which provides flow cytometry consultation, technical advice, flow cytometric analysis and cell sorting services as well as flow cytometric image analysis.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Indiana University Cooperative Center of Excellence in Hematology Angiogenesis Core

Core facility which conducts validated and reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

MMPC-University of Michigan Medical School Animal Care and Germ-Free Mouse Core

Core that provides services to the University of Michigan community and can also ship germ-free mice to locations worldwide. Its projects include studies investigating inflammatory bowel disease and cancer, host microbiome interactions, infectious disease pathogenesis, and mammalian and bacterial metabolism.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Indiana University Cooperative Center of Excellence in Hematology

Research center for hematology research. It provides services through four scientific core facilities: the Experimental Mouse Resources Core, the Optical Microscopy Services Core, the Angiogenesis Core, and the Flow Cytometry Core in addition to the Enrichment Program of the Center.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Indiana University Cooperative Center of Excellence in Hematology Experimental Mouse Resources Core

Core facility which maintains on-site breeding colonies of mouse strains essential for study of murine and human hematopoietic cells in vivo. It also provides specialized core services and consultation to CHSCC investigators and serves as an educational resource for CHSCC laboratories.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

Center for Iron and Heme Disorders at the University of Utah

Research center for iron and hematology research. It hosts cores that provide services for mutation generation and detection, metabolomics, and iron and heme experiments and research. In addition to these cores, it has an Enrichment Program, and Internal and External Advisory Committees, and a Pilot and Feasibility program.

Resource
SciCrunch
10 years ago - submitted by Kristen Jensen

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