Curator Dashboard

Private research university in Greater St. Louis with its main campus mostly in unincorporated St. Louis County, Missouri and Clayton, Missouri.

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• RRID-Legacy
• 7 years ago - submitted by Edyta Vieth

Central micro/nano fabrication facility of Northwestern University. Provides range of nanofabrication equipment and technical expertise. Supports research in all areas of science, engineering, medicine, and interdisciplinary fields.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core to apply advanced molecular genetic techniques in rodent models of physiology and disease. Generates novel mutant mouse strains by using gene targeting in embryonic stem cells (ESCs) and by developing novel methods of modifying rodent genomes and assaying genetically modified cells in vivo.Offers sperm and embryo cryopreservation and storage technologies for strain preservation and recovery.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility specializes in high resolution chemical imaging by three dimensional atom probe tomography. APT produces three-dimensional (3D) atom-by-atom elementally and isotopically resolved image with sub-nanometer spatial resolution of sample volume typically 100 x 100 x 300 nm^3, by simultaneous high resolution direct-space imaging and atom-by-atom time of flight mass spectrometry. APT is particularly suited to study nano- or nanostructured materials.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core offers multiple types of experiments from simple protein identification to protein quantitation (both relative and absolute), performs both traditional bottom-up proteomics, where proteins are digested with enzyme prior to analysis and intact, top-down proteomics analyses. Core proteomics specialists help guide your project to completion.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides high-resolution instruments capable of quantitatively imaging biologically essential elements in individual cells. Used for analyzing metal quotas at scales ranging from subcellular level to entire ecosystems.Provides access to imaging and quantification instrumentation while supporting its use with an expert technical staff that offers range of services, including instrument training, sample preparation and analysis, experiment design, and grant proposal assistance.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Shared use and training facility. Servies include Confocal Laser Scanning Microscopy, DIC (Differential Interference Contrast Microscopy), FCS (Fluorescence Correlation Spectroscopy), FLIP (Fluorescence-Loss-In-Photobleaching), FRAP (Fluorescence Recovery After Photobleaching),FRET (Fluorescence/ Forster Resonance Energy Transfer),Live-cell Imaging,Phase Contrast Microscopy,Widefield Fluorescence Microscopy,Image Processing and Analysis. Services include poster printing, and specimen preparation. Provides training for most instruments. Instruments include Leica DM6B Fluorescent Microscope (Hogan 5-112), Leica TCS SP8 Confocal Microscope (Hogan 5-128),Leica SP5 II Confocal Microscope (Hogan 5-114),Leica Spinning Disk Confocal Microscope (Hogan 5-113),DeltaVision Deconvolution Microscope (Hogan 5-111),Olympus IX83 Inverted Fluorescent Microscope (Silverman Hall 1-567),Olympus IX53 Inverted Color Microscope (Silverman Hall 1-567), LionHeart Automated Microscope BioTeck (Hogan 5-110).

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core facility that provides access to genome-wide collections of cDNAs and siRNAs that can be used to interrogate cellular models of signal transduction pathways and phenotypes. Services include cell lines, hit-picking clones and various screening sets, and access to equipment.Provides instruments:Analyst Molecular Devices,Embla Molecular Devices, Envision Perkin Elmer, Platemate Matrix, Tecan M200, Wellmate Matrix.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides expertise and resources for large scale biology. Helps to set up, run, gather data and perform analysis in drug discovery research, biochemistry, cell and organismal biology, functional genomic screening, and synthetic genetic. Works with proteins, nucleic acids, small model organisms, and microbial strains. Provides tissue culture,produces and uses lentivirus particles, screens compound libraries, does experiments for investigators,generates preliminary data to figure out if idea is workable, discusses project development. Services include Macromolecular binding, biochemical, and cell-based assays,High content screening with widefield or confocal optics,Nanoliter liquid handling up to 1536-well density,Whole-plate kinetic assays (ion currents, GPCR signaling),Compound library screening,CRISPR/Cas9 screening (multiplexed libraries),Analysis of large data sets,Fluorescence Thermal Shift assay (measures protein melting),Complex liquid handling work flows.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

ELISA for the detection of phosphorylated neurofilament H (pNF-H) in plasma, serum, cerebrospinal fluid, tissue extracts and other fluids. Elevate levels of pNF-H in blood and CSF indicate axonal injury and/or degeneration and are related to the onset and progression of a variety of serious diseases including amyotrophic lateral sclerosis, multiple sclerosis, traumatic brain injury and spinal cord injury.

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• SciCrunch
• 7 years ago - submitted by Gerry Shaw

ELISA for the detection of phosphorylated neurofilament H (pNF-H) in plasma, serum, cerebrospinal fluid, tissue extracts and other fluids. Elevate levels of pNF-H in blood and CSF indicate axonal injury and/or degeneration and are related to the onset and progression of a variety of serious diseases including amyotrophic lateral sclerosis, multiple sclerosis, traumatic brain injury and spinal cord injury.

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• SciCrunch
• 7 years ago - submitted by Gerry Shaw

Facility offers high throughput sequencing and library building services for UMass campuses and outside customers. Operates several types of Illumina next gen sequencers, and is closely integrated with PacBio Core Enterprise and Molecular Biology Core Labs.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides instrumentation for determination of crystal structures using X-ray diffraction techniques.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core offers light microscopy platforms providing guidance to researchers with their projects from sample preparation to data analysis, expertise in cellular imaging including live cell imaging, FRAP, FLIM, FRET, FCS, image correlation spectroscopy, TIRF, spectral imaging, high content screening, multi-photon imaging, laser capture micro-dissection, cellular image analysis, and custom image analysis, consultations, image processing, image analysis and preparation of data for publication.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core for full DNA and RNA analysis services. Canada's largest integrated provider of sequencing, genotyping and biochips services. Offers scientific community around the world genomic services in support of research in human health, agrifood, forestry and sustainable development.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility provides flow cytometric analysis and cell sorting services to all UConn researchers as well as researchers at neighboring institutions. Located on 6th floor of E building in room E6014, consists of lab space, complete with fume hood, centrifuge, and sink space and has instruments available for cellular analysis and cell sorters.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core to evaluate, select, and implement computational solutions for analysis of biological data.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Resource offers range of mass spectrometry instrumentation, expertise in analysis of RNA, RNA modifications, and proteins involved in RNA metabolism/regulation, supports projects involving analysis of biomolecules, metabolites, and small synthetic molecules, provides consulting on experimental design, sample preparation and data interpretation, whole project development and grant writing contributions.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core sassist users with all their microscopic imaging needs, from the conception of an idea, to final image analysis and presentation.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core for researchers who want to apply advanced molecular genetic techniques in rodent models of physiology and disease. Generates novel mutant mouse strains by using gene targeting in embryonic stem cells (ESCs) and by developing novel methods of modifying rodent genomes and assaying genetically modified cells in vivo.Offers sperm and embryo cryopreservation and storage technologies for strain preservation and recovery.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth