Curator Dashboard

Core facility for genomics research offers range of DNA sequencing, assistance and advising in planning, data acquisition, and data analysis. Provides genetic and genomic support to environmental and biomedical research projects. Creates education and training opportunities for students and professionals.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core for biological microscopy and image analysis. Offers high-end equipment,user training,ongoing support, including experiment design and data interpretation,twenty-four hour access Services,3D Printing, Transfer Files, Image Analysis,Histology,Instrument Training.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides investigators with access to imaging technologies and strategies to image live animals on organ, tissue, cell, or molecular level.Core for studying and monitoring disease in small living subjects.Performs noninvasive and nonlethal three-dimensional imaging. Equipped with instruments for micromagnetic resonance imaging, micropositron emission tomography, X-ray microcomputed tomography, bioluminescence and fluorescence scanning, and high-frequency ultrasound.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 20,2025. Core to study immune cell phenotype and function, characterizes antitumor immune responses, determines mechanisms of immune escape and evasion, and develops biomarkers that predict patient outcomes or possible toxicities. Offers services for immune monitoring,provides expert knowledge that guides choice of technologies used for study, coordinates purchase, quality control, and use of reagents. Stand-alone services include high-quality cell processing and storage to support correlative studies. These services allow convenient batched analysis of trial samples.Staff purifies peripheral blood mononuclear cells daily from clinic visits and another staff member is available for on-demand and after-hours processing. Samples are cryopreserved on-site in temperature-monitored LN2 freezers for short-term storage. For long-term storage, samples are transferred to Novare Biologistics,off-site cGMP-compliant, New York State-licensed, and FDA-registered biorepository. Routinely assess quality of processing and cryopreservation. Core meets performance targets for cell viability and recovery necessary for certification by Integrated Biobank of Luxembourg. Offers service for isolating tumor-infiltrating lymphocytes using dissociation protocols optimized for various tumor tissues. Offers flow cytometry at Perlmutter Cancer Center, along with expert service and training. Sterile fluorescence-activated cell sorting (17 colors) is routinely performed with options for high-speed (50K cells per second), single-cell deposition (into polymerase chain reaction plates), and BSL-3 sorting for unscreened or infected human material. Data analysis workstations are also available.Offers single-cell analysis through our cutting-edge 30-parameter flow cytometry technology and Integrated Molecular Cytometry Platforms (IMCPs).

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core offers custom metabolomics services,specializes in mass spectrometry based metabolomics, offering global (untargeted) and targeted methods for metabolite identification and quantification.Commonly assayed targets include glycolytic and tricarboxylic acid (TCA) cycle intermediates, amino acids, nucleotides, and lipids. Using custom-targeted method, we can perform absolute or relative quantification, flux analysis, and biotransformation analysis.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core offers comprehensive light and electron microscopy technologies. Our scientists use light microscopes and electron microscopes at resolutions ranging from centimeters to angstroms, providing clear and detailed images.We assist at every stage of your experiment, offering research-design consultation and instrument training, as well as guidance in study execution, analysis, and presentation for publication.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides liquid chromatography and gas chromatography mass spectrometry instrumentation for selective identification and reproducible quantification of trace-level biomolecules in complex samples. Services include qualitative, quantitative and structural analysis of proteins, lipids, metabolites, pesticides, pharmaceuticals and volatile organic compounds. Tests can be performed as long as molecules of interest are amenable to ionisation technique employed in source of mass spectrometer. Depending on instrument type, samples may be solid, liquid or gas. Mass spectrometry platforms include Liquid Chromatography Mass Spectrometry (LC-MS) and Gas Chromatography Mass Spectrometry (GC-MS). Analysis include volatile organic compounds (odour analysis),pharmacokinetics (bioavailability, bioefficacy),drug development (determining structures of drugs and metabolites),clinical testing (biomarkers discovery and endogenous compounds),genomics (oligonucleotide sequencing) epigenetics (global DNA methylation analysis),environmental research (testing water, soil, food and air quality).

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides fast, accurate, convenient, and affordable genotyping technologies. We use conventional polymerase chain reaction (PCR) and gel electrophoresis methods. By pooling samples from group of users, we can better ensure accuracy, cost-effectiveness, and quality control.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides mass spectrometers including Thermo Q Exactive Plus,Bruker impact II ,Bruker microflex LRF,Bruker ULTRAFLEX III,Shimadzu GCMS-QP2010S,Waters Acquity LCMS.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core mission is to drive scientific discovery through use of human specimens.Helps facilitate translational research, match human specimen resources to scientific needs, foster multi-investigator collaborative projects, and catalyze scientific innovation,improving researcher access to existing biospecimen resources, and enhancing institution-wide tissue-banking efforts and capacity. Another priority is to implement campus-wide policy for human biospecimen collection and storage to ensure regulatory compliance.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides range of services related to genome, epigenome, and transcriptome analysis. Offers technologies including Illumina deep sequencing and sample preparation for variety of applications, including DNA and RNA sequencing (DNA- and RNA-seq), exome sequencing, targeted capture, chromatin immunoprecipitation sequencing (ChIP-seq), methylation sequencing (Methyl-seq), metagenomics, and many others;Automation of Illumina library and targeted capture preps, including 16S ribosomal RNA (rRNA) sequencing;Oxford Nanopore sequencing (long reads);Bio-Rad Droplet Digita polymerase chain reaction (PCR);Nanostring nCounter;Single-cell RNA- and DNA-seq using the C1 Auto Prep System from Fluidigm, and 10x Genomics Chromium System.Provides expertise on strategies to achieve research goals in any field related to genomics, and can tailor bioinformatics analysis to individual project. If you supply us with nucleic acids, we can perform every step required to help you achieve your desired results.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides services, access to instruments, and training to facilitate production of animal tissue samples for morphological and molecular analyses. Supports multiplex immunofluorescence staining, RNA in situ hybridization (ISH), and imaging analysis. Services include tissue preparation, processing, and sectioning, as well as histochemistry and immunohistochemistry of fresh, frozen, and fixed animal tissues, can optimize and validate commercial or proprietary antibodies for chromogenic or fluorescence-based immunohistochemistry including seven-color multiplexing.Provides access to database listing antibodies that have been tested in lab to date and are currently in stock.Offers basic imaging resources and digital whole-slide scanning of stained tissue sections, which allows researchers to view their slides online at their convenience.Researchers can also rent our self-service instruments. These include embedding station, microtome, cryostat, and vibratome. Provides access to brightfield and fluorescence upright and dissecting microscopes,laser capture microdissection scope, and high-throughput multispectral imaging system.To reserve time on instrument, faculty, staff, and investigators must be registered in iLab.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides sample preparation, metal extraction, dissolved solids measurement, analytic consultation, and technical writing assistance) in support of wide range of clinical and biomedical research projects.Instruments include Agilent 5100 SVDV Inductively-Coupled Plasma-Optical Emission Spectrometer, SPS3 Robotic Autosampler,MARS5 Microwave Sample Digestion Oven,ICPExpert Advanced Workstation.Analytic Capabilities:Simultaneous, multi-element quantitation over wide dynamic range;Broad elemental detection capability with high precision and sensitivity;Compatible with range of clinical, nutritional, basic research, and pharmaceutical samples;Tolerant of high total dissolved solids and complex matrix components;NIST-traceable calibrants, standards, and other QA/QC controls included in analyses.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core offers specialized expertise for analysis of proteins and peptides using mass spectrometry. Develops new methods and customized approaches for proteomic analysis and suggests experimental strategies and sample preparation prior to mass spectrometry analysis. Services include:comprehensive protein identification ,analysis of affinity purified complexes,characterizing protein post-translational modifications,de novo sequencing,label and label-free quantitation ,multiplexed quantitation global phosphorylation and ubiquitin analysis,analysis of laser-capture microdissected formalin-fixed paraffin-embedded tissue,secretome analysis,crosslinking analysis,disulfide mapping.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides cell cultures (mammalian and insect), media, supplies and expertise and consultation regarding cell culture needs, media, and experimental design.Provides tested media, serum, and cell lines at exceptionally low prices, large scale production of cells, expansion and harvesting of hybridoma lines,cryopreservation of cell lines, Cell Authentication by STR analysis provided in conjunction with DNA Sequencing Facility, Mycoplasma screeening,Use of 2 laminar flow hoods for mammalian or insect cell manipulation.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core offers imaging modalities, techniques, and services for in vivo imaging of small animals and ex vivo imaging of tissue/organ specimens. iSAIRR sub-cores feature magnetic resonance imaging and spectroscopy (MRIS); optical imaging (bioluminescence and fluorescence); positron emission tomography, single photon emission computed tomography, and computed tomography (PET/SPECT/CT).Services include Assistance with experimental design,Assisted and/or independent image acquisition,Veterinary support for all imaging modalities,Assistance with data processing and interpretation.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Shared macromolecular x-ray crystallography facility provides instruments and expertise for screening, optimizing, imaging, growing, and storing crystals of biological macromolecules. The X-Ray Facility coordinates single crystal x-ray diffraction data collection at third generation synchrotron x-ray source using FSU's membership at the National Synchrotron Light Source II at Brookhaven National Lab, Upton, NY. XRF also offers custom buffer preparation, optimization, and crystal set-up using multi-well format crystallization blocks and plates.XRF has ARI Crystal Gryphon robot, Formulatrix Rock Imager, Formulator 16, Rock Maker software, RUMED incubator, Cryo storage and shipping dewars, Leica S8 AP0 Zoom microscope and other amenities.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides production of mouse models to support fundamental and translational research. Provides transgenic, gene targeting,DNA microinjection services, CRISPR/Cas9 microinjection, ES cell manipulation and other microinjection services to generate transgenic mice, knock-in/knock-out mice and chimeric mice harboring select genetic mutations. Other services include mouse sperm cryopreservation and recovery, in vitro fertilization (IVF), rederivation of pathogen free mouse lines and derivation of mouse embryonic stem cell lines. Provides general consultations on experimental designs and vectors for gene modification-related projects, DNA preparation, recombinant ES clones, mouse genotyping, colony breeding and husbandry, customize services as requested to support development of animal models for modeling human diseases.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides imaging capabilities, including magnetic resonance imaging, magnetoencephalolgraphy, electroencephalography, magnetocardiography, and ultrasound,expertise in cognitive neuroscience, neurobiology, biomedical physics, and computing, together with support team of technologists, nurses, research associates, and research assistants. Through strong collaborations, these individuals assist with study design, collection of data, analysis, and interpretation of results. HBIC supports investigators with new technique development, feasibility studies, pilot funding, preparing grant applications and manuscripts, and compliance. Carries out investigator-initiated research and research/clinical trials sponsored by public and private agencies. Offers education and training.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides access to NMR technology. Users can collect their own data, facility staff can do it all for you, or collaborative projects can be developed. Provides training in instrument operation and can offer advice for data analysis or project feasibility. Facility houses two 600 MHz Bruker Avance III spectrometers with cryogenically cooled probes.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth