Curator Dashboard

Core provides instruments for live cell imaging including Leica SP8-X confocal microscope and other fluorescence microscopes. Facility provides workstation for confocal image processing, ancillary equipment required for transmission electron microscopy. Services are provided as self services after user training by IMF staff or as full services done by core facility staff.

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• 6 years ago - submitted by Edyta Vieth

Standard model SZ61 Zoom Stereomicroscope with magnification range from 6.7x to 45x (using 10x eyepieces), with wide zoom ratio of 6.7:1, enabling macro to micro zooming that speeds routine workflows. Inward angle allows combination of high level flatness and depth of focus for 3D viewing.

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• 6 years ago - submitted by Raghava Jagadeesh

Microscope with differential interference contrast ,bright field, dark field components. TR30-2 Trinocular observation head with WH10X 22 eyepieces. 0.5X parfocal C mount camera adapter. Universal reflected and transmitted light stage. Capable of both transmitted and reflected light observations.

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• 6 years ago - submitted by Raghava Jagadeesh

Digitizer offers analog I/O, digital I/O, and four 32‑bit counters/timers for PWM, encoder, frequency, event counting, and more. Delivers functionality leveraging high throughput PCI Express bus and multicore optimized driver and application software. Suited for broad range of applications, from basic data logging to control and test automation.

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• 6 years ago - submitted by Raghava Jagadeesh

Two channel, differential amplifier by A-M Systems, intended for extracellular recording and/or stimulating with high impedance metal microelectrodes. Used for single cell spike recordings, applications requiring extracellular neurophysiological recording from excitable tissue such as nerve, muscle EMG, EEG, EKG, and ERG recordings. Each channel contains high gain, low noise differential amplifier stage followed by low pass, high pass, and notch filters. Three operating modes are available to accomodate recording, stimulating, and verification of electrode impedance.

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• 6 years ago - submitted by Raghava Jagadeesh

Flexible stimulus isolator since it is optically isolated. Unit can be switched to constant current or constant voltage. You can get bipolar pulses by connecting two isolators.

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• 6 years ago - submitted by Raghava Jagadeesh

Cluster microelectrode for recording or stimulation in chronic applications. Custom Microelectrode Code CE2C55 with Inner Pole Diameter 25 um and Length 50mm.

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• 6 years ago - submitted by Raghava Jagadeesh

Slice keeper holds four sets of brain slices and features container with lid and integrated air stone for bubbling carbogen into ACSF, needle valve for adjusting gas flow included, and curved bottom designed to keep bubbles away from slices while promoting fresh solution flow over slices.

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• 6 years ago - submitted by Raghava Jagadeesh

Software tool for visualizing research papers from computational psychiatry as two dimensional map. Shows distribution of papers along neuroscientific, psychiatric, and computational dimensions to enable anyone to find niche research and deepen their understanding of the field. Database for visualizing research papers.

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• 6 years ago - by Anonymous

Software R package for creation of HTML report of differential expression analyses of count data. Integrates some of code mentioned in DESeq2 and edgeR vignettes, and reports ranked list of genes according to fold changes mean and variability for each selected gene.

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• SciCrunch
• 6 years ago - by Anonymous

Software tool as image analysis and processing solution for quantitative microscopy which provides control of Leica microscopes and Leica digital cameras. Capability ranges from simple interactive image measurements to automatic, multi-parameter measurements. Available in editions including QWin Runner, QWin Lite, QWin Plus, QWin Standard and QWin Professional.

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• 6 years ago - by Anonymous

Portal for islet research community. Data for eight scRNA-seq datasets are combined to give consensus overview of islet cell type defining genes. Tools are provided for interacting with and comparing novel genesets generated.

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• SciCrunch
• 6 years ago - by Anonymous

Web tool where one component is front end Xena Browser and another component is back end Xena Hubs. Web based Xena Browser empowers biologists to explore data across multiple Xena Hubs with variety of visualizations and analyses. Xena Hubs host genomics data from laptops, public servers, behind firewall, or in cloud, and can be public or private. Xena Browser receives data simultaneously from multiple Xena Hubs and integrates them into single coherent visualization within browser. Allows users to explore functional genomic data sets for correlations between genomic and/or phenotypic variables.

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• 6 years ago - by Anonymous

Web tool as HMM plus similar protein based gene prediction. Used for multiple gene prediction in genomic DNA with using information from similar protein. Used if you know protein sequence similar with protein which is encoded by gene in your sequence.

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• SciCrunch
• 6 years ago - by Anonymous

Web server for macromolecular structure model optimisation and databank of optimised structure models. Focuses on automating final steps of crystallographic process: optimisation of structure model through refinement, rebuilding, and validation. Can automatically optimise most of crystallographic structure models based on input model and diffraction data. Web server works on user provided data, databank has updated versions of Protein Data Bank entries based on original experimental data that were deposited with atomic coordinates in PDB.

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• 6 years ago - by Anonymous

Web server for alignment of protein structures in presence of conformational changes. Used for 3D alignment of crystal structures of different protein molecules in presence of conformational change. Can identify structurally equivalent regions also when distant in terms of sequence and separated by other movable domains.

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• 6 years ago - by Anonymous

High-speed fluorescence-activated cell sorter (FACS) used in biological and medical research to analyze and physically separate specific types of cells from a complex mixture. It works by passing individual cells in a fluid stream past lasers and capturing target cells based on their unique light-scattering and fluorescent properties. Cell sorter features hardware and software enhancements that improve overall ease of use, flexibility,and aseptic capability. Offers new options in lasers and nozzles to support more advanced multicolor applications. Built on fixed alignment technology. FACSAria II cell sorter is first generation of BD FACSAria system where flow cell is in true fixed alignment with laser, to reduce startup time and improve reproducibility.

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• 6 years ago - by Anonymous

Software tool for limiting dilution analysis, with particular attention to needs of stem cell assays. Provides confidence intervals for all LDA data sets, including those with 0% or 100% responses. Other features include test of adequacy of single hit hypothesis, tests for frequency differences between multiple data sets, and ability to take advantage of cases where number of cells in sample is counted exactly.

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• 6 years ago - by Anonymous

Microplate Reader from Molecular Devices is ideal for UV-Vis life science applications, especially DNA analysis. Multi channel design mimics dual beam spectrophotometer. Each sample has discrete sample beam and reference beam so that each well is measured directly, eliminating error due to variations in light output between optic fibers. System consists of eight sample beams and detectors and eight reference beams and detectors to deliver both precision and speed of reading across microplate through 4.0 OD. Detects 16 ng per well of DNA and quantitates 50 ng of DNA.

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• 6 years ago - by Anonymous

Software R package to produce publication ready volcano plots with enhanced colouring and labeling. Used to visualise results of differential expression analyses.

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• 6 years ago - submitted by Christopher Haga