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Core catalyzes translation of scientific discoveries into novel protein cancer therapies. Offers therapeutic antibody and enzyme discovery, engineering, and optimization services.
Software Python package for the capture of provenance information during the execution of Python scripts that process data. Alpaca provides a simple API for recording the details of the functions being executed, the data flow, and a description of parameters used. Using simple Python decorators, this is accomplished with minimal code instrumentation and user intervention. Provenance information is structured and serialized according to a model based on the W3C PROV format. In addition, provenance information can be simplified and prepared for interactive visualization by the researcher.
Software application to Pan-cancer characterization of ncRNA synergistic competition. Used to predict ncRNA synergistic competition network from gene expression data and predicted ncRNA-related ceRNA networks.
Institutional resource collaboratively run by Office of Research Operations and Department of Pathology and Laboratory Medicine that provides services in support of Dartmouth Research Communities and in alignment with Institutional Review Board approved protocols including Clinical Trials. Provides collection, processing, storage, and distribution of annotated human bio-specimens to clinicians and other investigators in support of clinical trials, industry sponsored projects, and scientific investigations.
Company offers sample preparation solutions for Mass Spectrometry Imaging. HTX delivers customized solutions for sample preparation and workflow automation of advanced analytical platforms.
Sprayer builds on capabilities of HTX TM-Sprayer providing innovative M5 chassis, high velocity stage and heated sample holder drawer. Sample plate holder is mounted on drawer mechanism to allow easy loading of samples, better protection of user and better alignment of various plate types. New High-Velocity XY stage allows nozzle displacement speed of up to 5,600mm/min and expands process range. Super dry spray can be achieved at high flow rates of solvent further improving instrument performance. E/Z trough gutter design improves chemical containement and is easy to remove and clean. Bulkhead connectors are directly mounted on it to also allow easy access to in line filter.
Allows users to adjust both gas flow rate and nozzle velocity to control drying time, preventing analyte delocalization and formation of large matrix crystals, known to create hot spots on MALDI images. Allows to heat matrix solution as it is being applied to their sample. By increasing temperature of matrix solution, absorption of matrix into sample is increased, resulting in greater MALDI image resolution.
Sample preparation platform offering automated advanced MALDI matrix sprayer.
Allows liquid surface extraction of analytes on surfaces and further analysis in HPLC-MS detector. Surface sample to be analyzed is mounted in custom sample tray. Then optical image of mounted sample is acquired using flatbed scanner controlled with DropletProbe Premium software.
Automated MALDI matrix deposition system offering speed, reproducibility, and smallest available crystals for sub-micron resolution mass spectrometry imaging. Features rectangular vacuum chamber that achieve sublimation conditions extremely quickly to maximize efficiency for imaging MS sample preparation.
Software tool for simulation, computation, and visualization of low compexity regions in biological data. Used for alignment free simulation, mapping, and visualization of low complexity regions in FASTA data. Provides ability of fast sequence characterization through low complexity regions, ideally for scenarios entangling presence of new or unknown sequences. Effective in whole genomes, specifically those reconstructed with support of long reads.
Imaging and cytometry facility of the Montpellier area.
Software R package to analyze oligonucleotide arrays at probe level. Supports Affymetrix (CEL files) and NimbleGen arrays (XYS files). Used for annotation of Affymetrix Gene Array data.
CKX41 inverted microscope suitable for regular cell observation including GFP and other fluorescence applications. High angle tilting head is for simple visual checks, while advanced Universal Infinity System 2 (UIS2) optics produce images. Olympus relief contrast increases visibility with non-glass cell culture vessels and improves productivity with its pre centered slider. Post acquisition analysis, documentation, and archiving can be achieved with digital cameras and software.
Scientific microscope camera for documentation and image analysis. Has dynamic range of 64 dB allowing users to image unevenly lit samples. Allows for long exposure times of several minutes.
Structured curated collection of protein based and of metabolic human molecular pathways. Human molecular pathways database with tools for activity calculating and visualization.All pathways are functionally classified according to GO terms enrichment patterns. All pathway participants, their interactions and reactions are uniformly processed and annotated, and are ready for numeric analysis of experimental expression data.For every comparison graph is generated summarizing top up and down regulated pathways.
Software library to calculate Pathways Activation Levels. It takes file that contains gene symbols in HGNC format, their expression levels for one or more samples and calculates PAL values for each pathway in each sample.
Video based phenotyping platform for laboratory mouse. Provides complete details of software and hardware, including 3D designs used for data collection. Data acquisition system consists of video collection hardware and software, behavior labeling and active learning app, and online database for sharing classifiers. Hardware and software solution collects high quality data for behavior analysis.