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The Handbook of Genetic Counseling is a wikibook designed as an introduction to the discipline and practice of genetic counseling. The text provides an introduction to genetic counseling as a clinical practice and includes sample counseling outlines and letters for students of genetic counseling. Additional outline and letter examples are highly encouraged. Wikibooks contains books on many medical topics; however, no warranty whatsoever is made that any of the books are accurate.

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• SciCrunch
• 16 years ago - by Anonymous

Draft release 3 for genome-wide SNP genotyping and targeted sequencing in DNA samples from a variety of human populations (sometimes referred to as the HapMap 3 samples). This release contains the following data: * SNP genotype data generated from 1184 samples, collected using two platforms: the Illumina Human1M (by the Wellcome Trust Sanger Institute) and the Affymetrix SNP 6.0 (by the Broad Institute). Data from the two platforms have been merged for this release. * PCR-based resequencing data (by Baylor College of Medicine Human Genome Sequencing Center) across ten 100-kb regions (collectively referred to as ENCODE 3) in 712 samples. Since this is a draft release, please check this site regularly for updates and new releases. The HapMap 3 sample collection comprises 1,301 samples (including the original 270 samples used in Phase I and II of the International HapMap Project) from 11 populations, listed below alphabetically by their 3-letter labels. Five of the ten ENCODE 3 regions overlap with the HapMap-ENCODE regions; the other five are regions selected at random from the ENCODE target regions (excluding the 10 HapMap-ENCODE regions). All ENCODE 3 regions are 100-kb in size, and are centered within each respective ENCODE region. The HapMap 3 and ENCORE 3 data are downloadable from the ftp site.

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• SciCrunch
• 16 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. An experiment management system for researchers studying language organization in the brain. Data from thirteen patients are available as a public demo. Language Map EMS

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• SciCrunch
• 17 years ago - by Anonymous

OSCAR is software for the semantic annotation of chemistry papers. The modules OPSIN (a name to structure converter) and ChemTok (a tokeniser for chemical text) are also available as standalone libraries. This tool for shallow, chemistry-specific parsing of chemical documents identifies (or attempts to identify): * Chemical names: singular nouns, plurals, verbs etc., also formulae and acronyms, some enzymes and reaction names. * Ontology terms: if you can do it by string-matching, you can get OSCAR to do it. * Chemical data: Spectra, melting/boiling point, yield etc. in experimental sections. In addition, where possible the chemical names that are detected are annotated with structures, either via lookup or name-to-structure parsing (OPSIN), and with identifiers from the chemical ontology ChEBI Current work on OSCAR3 by Peter Corbett focuses on its use in SciBorg, a framework for the deep parsing of chemical text. OSCAR3 also includes the Oscar Server, a Jetty-powered set of servlets. These provide the following services: * Parsing of text/HTML by OSCAR. * Text/InChI/SMILES/SMILES substructues/SMILES similarity search of papers, coupled with keyword and ontology-based search, using Lucene and the CDK. * List of all names found / all names that co-occur with a search term or terms. * Online management of a chemical/stopword lexicon. * Manual editing of SciXML fragments containing named entities, for creating of gold standards and training data. Oscar3 can be found on SourceForge: http://sourceforge.net/projects/oscar3-chem/

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• SciCrunch
• 16 years ago - by Anonymous

Established in 1970, the University of Miami Tissue Bank (UMTB) is the oldest academic institution of its kind in the United States. UMTB came about and evolved in an effort to provide safe and effective bone and soft tissue grafts to patients long before allograft bone transplantation was widely accepted. UMTB has always been focused on safety and the advancement of knowledge in allograft use. More scientific peer-reviewed articles, book chapters and innovations have come from UMTB either directly or indirectly than from any other organization of its kind. UMTB continues to be a leader in transplantation research and has maintained an impeccable safety record. As the only university-run tissue bank, UMTB works closely with surgeons and basic science investigators to advance the field of bone and soft tissue transplantation. Our scientific endeavors include clinical trials to confirm and improve graft efficacy for oral surgery, orthopedic tumor and spine surgery, and sports injuries. When warranted, we engage commercial entities for these studies. As a multidisciplinary organization of surgeons, pathologists, scientists and technicians, we have safely recovered, processed, distributed and implanted aseptically processed bone, cartilage and soft tissue grafts in thousands of patients. We make extraordinary efforts to ensure aseptic recovery and processing to protect the biologic activity, integrity, bio attributes, and safety of the graft. We believe that the American Association of Tissue Banks (AATB) has adopted appropriate guidelines for Tissue Banking in the United States and the University of Miami is a proud member of this organization.

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• SciCrunch
• 16 years ago - by Anonymous

Resource for the storage, retrieval and annotation of plant ESTs, with a focus on comparative genomics. PGN comprises an analysis pipeline and a website, and presently contains mainly data from the Floral Genome Project. However, it accepts submission from other sources. All data in PGN is directly derived from chromatograms and all original and intermediate data are stored in the database. The current datasets on PGN come from the floral genome project and includes the following species: Acorus americanus, Amborella trichopoda, Asparagus officinalis, Cucumis sativus, Eschscholzia californica, Eschscholzia californica, Illicium parviflorum, Ipomopsis aggregata, Liriodendron tulipifera, Mesembryanthemum crystallinum, Mimulus guttatus, Nuphar advena, Papaver somniferum, Persea americana, Prymnesium parvum, Ribes americanum, Saruma henryi, Stenogyne rugosa, Vaccinium corymbosa, Welwitschia mirabilis, Yucca filamentosa, Zamia fischeri. For functional annotation, blast is used to compare find the best match of each unigene sequence to in the Genbank NR database, and the in complete coding sequences from Arabidopsis. These annotations are stored in the database and serve as the primary source of annotation. The annotation framework will be extended to Gene Ontology annotations in the future.

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• SciCrunch
• 16 years ago - by Anonymous

CAS REGISTRY, the gold standard for substance information, is the only integrated, comprehensive source of chemical information from a full range of disclosed material including patents, journals, and reputable web sources. When you need to positively identify a chemical substance, you can rely on the authoritative source for chemical names and structures of CAS REGISTRY. CAS databases are curated and quality-controlled by CAS scientists, and recognized by chemical and pharmaceutical companies, universities, government organizations, and patent offices around the world as authoritative. By combining these databases with advanced search and analysis technologies (SciFinder, STN, and Science IP products and services), CAS delivers the most current, complete, and cross-linked secure digital information environment for scientific discovery. You can identify your substance of interest by its CAS Registry Number, which is the best way to identify a substance, regardless of what name you have for it. You can also use CAS REGISTRY to locate * literature references to the substance * experimental and predicted property data (boiling and melting points, etc.) * commercial availability * preparative methods * spectra * regulatory information from international sources

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• SciCrunch
• 16 years ago - by Anonymous

Software package provides statistical tools. Derives copy number and BAF from variety of NGS data including WES, WGS, targeted panel, and shallow sequencing as well as Microarray data. Multifaceted desktop software for rapid discovery of genomic alterations. Accepts data from various manufacturers and technologies including Infinium GSA and CytoScan XON.

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• SciCrunch
• 13 years ago - by Anonymous

The IBC Research Foundation BioBank is a secure, privacy-protected collection of biological specimens from ibc-diagnosed patients (cases, and, unlike the former George Washington University IBC Registry, ibc patients who have died, those who are under legal age, and those living but unable to make decisions for themselves, may be consented to participate in the IBC Research Foundation BioBank by their authorized representative) and from those not diagnosed with ibc (controls), volunteering following a consent decision making process, and signing an Informed Consent. Clinical Data and a comprehensive questionnaire will also be obtained for those diagnosed with ibc. The Inflammatory Breast Cancer Research Foundation (ibcRF) has established a BioBank and Clinical Database. The BioBank contains non-tumor RNA and DNA, tumor RNA and DNA, blocks and slides from diagnostic pathology, and medical records describing clinical and pathologic findings at diagnosis.

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• SciCrunch
• 16 years ago - by Anonymous

Established in 1987, LifeGift is a not-for-profit organ procurement organization that recovers organs and tissue for individuals needing transplants in 109 Texas counties in North, Southeast and West Texas. Our Role * Help grieving families consider the decision to give the gift of life. Inform families of registered donors of their loved ones����?? wishes to donate. * Coordinate the organ and tissue recovery process with surgeons, other transplant professionals and transplant centers. Collect data for use in transplantation research. * Partner with hospitals to continually develop effective, government-regulated donation systems to help increase the number of donated organs available for transplant. * Educate the public about the need for organ and tissue donation. Serve the African-American, Latino and Asian minority communities with specific educational programs. * Continue to support and maintain contact with donor families following the donation process, facilitating communication between recipients and donor families, if both parties desire.

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• SciCrunch
• 16 years ago - by Anonymous

An affiliation of organ and tissue recovery organizations across the United States that is committed to saving and improving lives by connecting one life to another through donation and transplantation. DCI Donor Services (DCIDS) supports families who have sustained the loss of a loved one by providing an opportunity for organ, eye and tissue donation and by facilitating the recovery and transplantation of these gifts to help others in need. They also provide after-care support to donor families while at the same time working to inspire universal acceptance of donation throughout the hospitals and communities we serve to ensure every person in need receives the Gift of Life.

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• SciCrunch
• 16 years ago - by Anonymous

Welcome to the website of the Fourth International Conference on Science in Society, to be held at the University of California, Berkeley, USA from 17 to 19 November 2012. This Conference will address disciplinary and interdisciplinary challenges in the sciences, and in particular the relationships of science to society. Key themes addressed by the Conference include the social impacts of science, the values and ethics of science, the pedagogies of science, the knowledge-making processes of science, the politics of science and the economics of science. At first glance, the scope and concerns of the Conference are enormous. However, in contrast to conferences with a specialist disciplinary focus, this Conference aims to explore, in an interdisciplinary spirit, linkages between different areas of concern and practices of investigation. We welcome presentation proposals which range from broad explorations of philosophical, theoretical, methodological and policy questions, to proposals which present finely grained evidence of the connections of science to society in microcosms of research, teaching and practice. Participants at the Conference will include researchers, teachers, administrators and policy makers from the basic natural-physical sciences, the applied sciences, the social sciences, history and philosophy of science, the humanities, and the professions. Plenary speakers will include some of the world's leading thinkers in the various fields which are concerned with the relationships of science to society, as well as numerous paper, colloquium and workshop presentations by practitioners, teachers and researchers. Participants are welcome to submit a presentation proposal either for a 30-minute paper, 60-minute workshop, or a jointly presented 90-minute colloquium session. Parallel sessions are loosely grouped into streams reflecting different perspectives or disciplines. Each stream also has its own talking circle, a forum for focused discussion of issues. For those unable to attend the Conference in person, virtual participation is also available. We encourage all presenters to submit written papers to The International Journal of Science in Society, a fully refereed academic Journal. Virtual participants may also may also submit papers for consideration by the Journal. All Conference participants who have finalized their registration will receive a complimentary online subscription to the Journal. This subscription is valid until one year after the Conference end date. If you would like to know more about this Conference, bookmark the Science in Society site and return for further information-the site is regularly updated. You may also wish to subscribe to the Conference and Journal Newsletter.

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• SciCrunch
• 16 years ago - by Anonymous

CFC International holds the world''s largest collection of blood and tissue from people affected by CFC and their immediate relatives. It is the only centralized repository in the world. The CFC BioBank provides medical researchers with genetic and biological material from CFC patients and their families, so that research on CFC and other related syndromes can be performed. CFC International joined the Genetic Alliance BioBank in 2004 to make certain that your privacy and confidentiality are protected and your samples are available to any approved research project. The bank serves as a resource for researchers around the world who are willing to search to find the gene(s) responsible for the Cardio-Facio-Cutaneous Syndrome. As you know, Cardio-Facio-Cutaneous Syndrome is an extremely rare condition. Thus while access to cell lines is essential for studying the biology and genetics of the disorder, there are very few cell lines in existence. Because an integral part of CFC''s mission is to stimulate interest in CFC research, there is an increased need for cell lines. The CFC BioBank will ensure that need is met! The goals of The CFC BioBank are to promote: * Sufficient availability of cells for approved research projects * Incentive for new research projects * Study of the biochemical basis for CFC Syndrome * Discoveries leading to new treatments for children with CFC Syndrome If you are interested in donating to the CFC BioBank please call 607-772-9666, or e-mail us at bconger_at_cfcsyndrome.org and indicate your interest. Researchers with an interest in either donating CFC Syndrome cell lines or in applying to use material from the bank should also call or write.

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• SciCrunch
• 16 years ago - by Anonymous

Established in 2004, SPH Biorepository was built to create a centralized facility for many research programs, as well as for new ones; more effective use of the available storage space; development of new database management tools; and quality control of sample processing and banking. While maintaining ultimate control of the samples accumulated in their research projects, PIs will have the assurance of competent handling of their biological samples, reliable access, safe storage, and expert advice from the Biorepository personnel. In the long-term, the Biorepository will provide: * Safe and orderly storage of banked samples * Samples diversification in case of a major disaster *Leverage for additional funding for the new projects Over 145,000 thousands of various biological and environmental samples have been stored and archived through the CHAMACOS, Vitamin, FACES, IBD, and other projects. The Biorepository (Holland - Director) has accumulated substantial expertise in the development of customized databases to barcode and monitor sample location, transfer, and use.

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• SciCrunch
• 16 years ago - by Anonymous

This project explores the use of a wiki as an online collaborative tool for improving and updating peer-reviewed systematic reviews. Posted on this wiki is a copy of the article: Second-line therapy in patients with type 2 diabetes inadequately controlled with metformin monotherapy: A systematic review and mixed treatment comparisons meta-analysis. Readers are invited to edit the article by adding to, deleting or modifying its contents.

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• SciCrunch
• 16 years ago - by Anonymous

This is a blog that combines an update of the current scientific research on psychology (and all its related disciplines) along with criticism, personal thoughts and commentary. Since psychology, along with its many other facets, is a social science I consider its connection with society to be an essential part of it. Therefore, the criticism and the commentary I make will often take things to the larger scale of society whether the research concerns neurology, cognitive psychology or anything else. Holding true to this spirit, this blog will many times incorporate current news from all over the world in an attempt to establish the missing link that differentiates mainstream psychology from the real out-of-the-lab world. I hope that this blog really brings something different to just a simple updating of the current research, because there are, indeed, many blogs that do this job. The author describes this blog as some occasional psycho-rant by a former student (now graduate) of psychology (and post graduate in artificial intelligence), while combining of course an update on the current research with a critical view and the occasional satiric spirit.

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• SciCrunch
• 16 years ago - by Anonymous

Samaritan Health Services (SHA) is a non-profit network of hospitals, physician clinics and health services caring for the communities of the mid-Willamette Valley and central Oregon Coast. We''ve joined together to provide innovative medicine and world-class quality in a way that''s consistent with the values of the places we serve. That includes care and compassion for everyone, regardless of the ability to pay. Samaritan Health Services is a values-driven, church-related organization governed by community members, physicians and other health care providers. We seek to be the first choice of consumers in the region and to lead collaborative efforts among those who share similar goals.

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• SciCrunch
• 16 years ago - by Anonymous

OpenAnesthesia.org is a wiki promoting evidence-based medicine in anesthesiology, critical care and pain management. It is divided into several, major Units (Anesthesia Text, Critical Care Manual, Practice-Changing Articles, Controversies in Anesthesia, ABA keywords, Audio/Video Archives, CME, GME, Pharmacology...), each of which is subdivided into Chapters (or in some cases, even smaller subdivisions, such as sections, individual key words, topics, points of interest, or bibliographic references). The goal of Anasthesia Text is to collect and distribute evidence-based information regarding all aspects of anesthesia. This section is similar to a traditional textbook in the broad range of topics covered, but different in that it will provide this information in the form of a wiki (i.e. anyone can edit, add, or subtract to it). OpenAneshesia.org provides anesthesia residents with GME credit and Program Directors with a tool to document core competency activities for Accreditation Council for Graduate Medical Education (ACGME)-mandated learning portfolios. Residents are invited invited to read the Anesthesia & Analgesia article of the month and listen to an interview with one of the article''s authors. During the interview, the author will discuss the specifics of the article as well as general topics geared towards improving each resident''s appreciation of basic or clinical research. After listening to the podcast and reading the article, residents can answer 5 questions in order to demonstrate their mastery of the topics discussed (similar to the Anesthesia & Analgesia Continuing Medical Education (CME) section). Like the CME section, after demonstrating proficiency, a resident will receive a printable certificate that will specify which ACGME core competencies were addressed in the article and interview. The certificates can be put in each resident''s ACGME-required learning portfolio.

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• SciCrunch
• 16 years ago - by Anonymous

Established in 1985, LifeLink Tissue Bank is a not-for-profit organization dedicated to serving patients in need of transplantation therapy. It is one of five divisions of the LifeLink Foundation and the largest not-for-profit tissue bank in the Southeast and one of the largest in the United States. LifeLink Tissue Bank is inspected and accredited by The American Association of Tissue Banks (AATB). Our goal is to provide the safest, most clinically effective allografts while remaining cognizant of the rising cost of medical care. Donors and their families are the core of our organization. We treat them with respect, show them compassion, and offer them comfort in knowing that their confidentiality is protected and their gifts optimally utilized. Our allografts are utilized by surgeons and hospitals that trust LifeLink to provide them with safe and clinically effective allografts. Every effort is made to ensure that our allografts are placed back in the hospitals of the communities that we serve with organ and tissue recovery services.

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• SciCrunch
• 16 years ago - by Anonymous

Central repository of information on neuronal cell types mainly accumulating information on: Genetically labeled cell types in mouse brain and genetically engineered mouse lines for cell type research. Mouse lines are annotated with * Atlas for examining transgene expression patterns * Information on construct used to generate transgene * Associated publications * Anatomical regions where transgene is expressed (based on Atlas) * Information on where to obtain the animals Currently, the mouse lines in the database are mostly generated at Cold Spring Harbor Lab, Scripps Research Institute, Baylor College of Medicine and Brandeis University with few other exceptions. In the future, they will incorporate more mouse lines useful for neuronal cell type research. Cell types are annotated with * Anatomical region * Properties (frequently used terms in neuroscience research) * Mouse line used to define the cell type * Genome wide transcriptome data (if available) * Specific (marker) genes (if available) * Marker immunostaining data (if available) * Associated publications * Electrophysiological characterizations (when available) * Morphological characterizations (when available)

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• SciCrunch
• 16 years ago - by Anonymous