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Showing 20 out of 28,805 Resources on page 1053

LumbriBASE

LumbriBASE is aa research tool for both Earthworm biology and environmental pollution monitoring.It provides a simple, easy-to-use access point to the publicly available Lumbricus rubellus sequence and functional data. It is a research tool for both Earthworm biology and environmental pollution monitoring. It is currently being developed by the Worm Consortium.

  • Resource
  • SciCrunch
  • 17 years ago - by Anonymous

LPFC: A Library of Protein Family Cores

LPFC is a database of structural alignments of protein families and computed average core structures for each family. The core structures can be divided into residues with low spatial variation and those with high spatial variation. Amino acids with low spatial variance occupy essentially the same relative position in all family members. This library is useful for building models, threading, and exploratory analysis. It is also a useful mechanism for summarizing variability in NMR structures., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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  • SciCrunch
  • 17 years ago - by Anonymous

LipOXygenases DataBase

The lipoxygenases database (LOX-DB) aims to be a web accessible compendium of information in particular on the mammalian members of this multigene family. This resource includes molecular structures, reference data, tools for structural and computational analysis as well as links to related information maintained by others. The data can be retrieved by the use of various search options and analyzed applying publicly available visualization tools. Lipoxygenases are a family of enzymes involved in a variety of human diseases like inflammation, asthma, artherosclerosis and cancer.

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  • SciCrunch
  • 17 years ago - by Anonymous

LOCATE: subcellular localization database

LOCATE is a curated database that houses data describing the membrane organization and subcellular localization of proteins from the RIKEN FANTOM4 mouse and human protein sequence set. The membrane organization is predicted by the high-throughput, computational pipeline MemO. The subcellular locations were determined by a high-throughput, immunofluorescence-based assay and by manually reviewing peer-reviewed publications.

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  • SciCrunch
  • 17 years ago - by Anonymous

Lipase Engineering Database

Database that integrates information on sequence and structure of lipases and related proteins sharing the same a/b hydrolase fold to facilitate protein engineering. Users can browse the database by classification, organism, hierarchic tree, and structure. They can also perform homology searches against the lipase database, and query the Lipase Engineering Database using SQL.

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  • SciCrunch
  • 14 years ago - by Anonymous

Legume Information System

LIS is a publicly accessible legume resource that integrates genetic and molecular data from multiple legume species and enables cross-species genomic, transcript and map comparisons. The intent of the LIS is to help researchers leverage data-rich model plants to fill knowledge gaps across crop plant species and provide the ability to traverse between interrelated data types. LIS, a component of the Model Plant Initiative (MPI), is being developed as part of a cooperative research agreement between the National Center for Genome Resources (NCGR) and the USDA Agricultural Research Service (ARS).

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  • SciCrunch
  • 17 years ago - by Anonymous

LEGER: the post-genome Database for Listeria Research

Knowledge database and visualization tool for comparative genomics of pathogenic and non-pathogenic Listeria species.Provides information on gene functions (as annotated or supposed by literature from homologous organisms) , protein expression levels under defined experimental conditions ,subcellular localization of proteins (expected and/or experimentally validated) , biological meaning of genes and proteins based on KEGG, InterPro and Gene Ontology.

  • Resource
  • SciCrunch
  • 17 years ago - by Anonymous

KinMutBase: A registry of disease-causing mutations in protein kinase domains

KinMutBase is a comprehensive database of disease-causing mutations in protein kinase domains. The current release of the database contains 582 mutations in 20 tyrosine kinase domains and 13 serine/threonine kinase domains. The database refers 1790 cases from 1322 families. KinMutBase is a registry of mutations in human protein kinases related to disorders. Kinases are essential cellular signaling molecules, in which mutations can lead to diseases, including immunodeficiencies, cancers and endocrine disorders. Mutations appear both in conserved hallmark residues of the kinases as well as in non-homologous sites. The KinMutBase WWW pages provide plenty of information, namely mutation statistics and display, clickable sequences with mutations and changes to restriction enzyme patterns.

  • Resource
  • SciCrunch
  • 17 years ago - by Anonymous

Islander

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 17, 2022. Islander is a comprehensive online database containing genomic islands discovered in completely sequenced bacterial genomes by the algorithm. Islands are transmitted between prokaryotic strains and therefore play a major role in genome evolution. An island often encodes an integrase gene that specifies the island''s position in the host genome. Usually integrases specify tRNA genes, and the island splits the the tRNA gene when it integrates. However the island also carries sequence that replaces the split-off portion, restoring an intact tRNA gene. Thus an island is often marked by a tRNA gene at one end, and a fragment of that gene at the other end. The islands in this database were identified using this principle through the following procedure: :1. Search for tRNA and tmRNA genes using tRNAscan-SE and BRUCE on whole prokaryotic genomes. :2. Search for significant hits to each tRNA and tmRNA gene using BLAST against the source genome. :3. Narrow down hits to those containing integrase genes (required for site-specific integration into the host genome). :4. Remove false positives (e.g., tRNA gene fragment not from end of gene, or in wrong orientation). :5. Enter into mysql database, display on website using Perl CGI pages., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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  • SciCrunch
  • 17 years ago - by Anonymous

NECTAR

A database and web application to annotate disease-related and functionally important amino acids in human proteins., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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  • SciCrunch
  • 13 years ago - by Anonymous

ISED- Influenza Sequence and Epitope Database

It catalogues the influenza sequence and epitope information obtained in Asia and currently hosts a total of 33388 influenza A and 4762 influenza B virus sequence data collected in 21 countries, and a total of 545 amantadine-resistant influenza virus sequences collected in Korea. ISED provides users with pre-built application tools to analyze sequence alignment and difference patterns and allows users to visualize epitope matching structures.

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  • SciCrunch
  • 17 years ago - by Anonymous

IRIS - International Rice Information System

IRIS is the rice implementation of the International Crop Information System (ICIS) which is a database system that provides integrated management of global information on genetic resources and crop cultivars. This includes germplasm pedigrees, field evaluations, structural and functional genomic data (including links to external plant databases) and environmental (GIS) data.

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  • SciCrunch
  • 17 years ago - by Anonymous

IRESite

Database of experimentally verified IRES structures. Presents information about experimentally studied Internal Ribosome Entry Site segments.

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  • SciCrunch
  • 17 years ago - by Anonymous

IRESite

Database of experimentally verified IRES structures. Presents information about experimentally studied Internal Ribosome Entry Site segments.

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  • SciCrunch
  • 17 years ago - by Anonymous

iProLINK

iProLINK (integrated Protein Literature, INformation and Knowledge) has been developed as a resource to facilitate text mining in the area of literature-based database curation, named entity recognition, and protein ontology development. The collection of data sources can be utilized by computational and biological researchers to explore literature information on proteins and their features or properties. The data sources for bibliography mapping and feature evidence attribution include mapped citations (PubMed ID to protein entry and feature line mapping) and annotation-tagged literature corpora. The latter includes several hundred abstracts and full-text articles tagged with experimentally validated post-translational modifications (PTMs) annotated in the PIR protein sequence database.

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  • SciCrunch
  • 17 years ago - by Anonymous

University of Rome Tor Vergata; Rome; Italy

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  • SciCrunch
  • 15 years ago - submitted by Eddy Kim

L1Base

L1Base is a dedicated database containing putatively active LINE-1 (L1) insertions residing in human and rodent genomes: a) intact in the two ORFs, full length L1s (FLI-L1s) and b) L1s with intact ORF2 but disrupted ORF1 (ORF2-L1s). In addition, due to their regulatory potential, the full length (&gt;6000bp) non-intact L1s (FLnI-L1s) were also included in the database.

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  • SciCrunch
  • 17 years ago - by Anonymous

IPD-MHC- Major Histocompatibility Complex

The IPD - MHC Database provides a centralized repository for sequences of the major histocompatibility complex from a number of different species. Through a number of international collaborations IPD is able to provide the MHC sequences of different species. The sequences provided by each group are curated by experts in the field and then submitted to the central database.

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  • SciCrunch
  • 17 years ago - by Anonymous

IPD-KIR - Killer-cell Immunoglobulin-like Receptors

The IPD-KIR database provides a centralized repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.

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  • SciCrunch
  • 17 years ago - by Anonymous

IPD-HPA - Human Platelet Antigens

A centralised repository for the data which define the human platelet antigens (HPA). Alloantibodies against human platelet antigens are involved in neonatal alloimmune thrombocytopenia, post-transfusion purpura and refractoriness to random donor platelets. The Human Platelet Antigen (HPA) nomenclature system was adopted in 1990 to overcome problems with the previous nomenclature. Since then more antigens have been described and meanwhile the molecular basis of many has been resolved, and the nomenclature was revised in 2003.

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  • SciCrunch
  • 17 years ago - by Anonymous