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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00047250
Source Database: WormBase (WB)
Affected Genes: WBGene00001207(egl-43)
Genomic Alteration: WBGene00001207(egl-43)
Availability: unknown
Source References: EMPTY
Synonyms: egl-43(bmd136[LoxP::gfp::egl-43(long)]) II.
Notes: GFP reporter inserted into N-terminus of endogenous egl-43 locus specifically tags the long isoform. Reference: Medwig-Kinney TN, et al. Development. 2020 Jan 2;147(1).|"Made_by: Taylor N. Medwig-Kinney"
Proper citation: RRID:WB-STRAIN:WBStrain00047250 Copy
http://www.wormbase.org/db/get?name=WBStrain00047253
Source Database: WormBase (WB)
Affected Genes: WBGene00000911(daf-15)
Genomic Alteration: WBGene00000911(daf-15)
Availability: unknown
Source References: EMPTY
Synonyms: daf-15(re147[daf-15::mNG::2xHA]) IV.
Notes: Made_by: Tam Duong|"mNeonGreen tag inserted at 3' end of endogenous daf-15 locus. Ubiquitous expression."
Proper citation: RRID:WB-STRAIN:WBStrain00047253 Copy
http://www.wormbase.org/db/get?name=WBStrain00047243
Source Database: WormBase (WB)
Affected Genes: WBGene00013462(micu-1)
Genomic Alteration: WBGene00013462(micu-1)
Availability: unknown
Source References: EMPTY
Synonyms: micu-1(ju1155) IV/nT1 [qIs51] (IV;V).
Notes: Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested nT1[qIs51] aneuploids, and non-GFP micu-1 homozygotes. Homozygous nT1[qIs51] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Tang NH, et al. Curr Biol. 2020 Jan 15. pii: S0960-9822(19)31694-X. doi: 10.1016/j.cub.2019.12.061.
Proper citation: RRID:WB-STRAIN:WBStrain00047243 Copy
http://www.wormbase.org/db/get?name=WBStrain00047244
Source Database: WormBase (WB)
Affected Genes: WBGene00013462(micu-1)
Genomic Alteration: WBGene00013462(micu-1)
Availability: unknown
Source References: PMID:31983639
Synonyms: micu-1(ju1783[micu-1::gfp]) IV.
Notes: GFP reporter inserted into C-terminus of endogenous micu-1 locus. Diffuse GFP signals throughout the body. Reference: Tang NH, et al. Curr Biol. 2020 Jan 15. pii: S0960-9822(19)31694-X. doi: 10.1016/j.cub.2019.12.061.
Proper citation: RRID:WB-STRAIN:WBStrain00047244 Copy
http://www.wormbase.org/db/get?name=WBStrain00047248
Source Database: WormBase (WB)
Affected Genes: WBGene00001207(egl-43)
Genomic Alteration: WBGene00001207(egl-43)
Availability: unknown
Source References: PMID:37039075
Synonyms: egl-43(bmd88[LoxP::gfp::egl-43]) II.
Notes: GFP reporter inserted internally into endogenous egl-43 locus. Reference: Medwig-Kinney TN, et al. Development. 2020 Jan 2;147(1).|"GFP::EGL-43 endogenous tag"|"Made_by: Taylor N. Medwig-Kinney"
Proper citation: RRID:WB-STRAIN:WBStrain00047248 Copy
http://www.wormbase.org/db/get?name=WBStrain00047249
Source Database: WormBase (WB)
Affected Genes: WBGene00001949(hlh-2)
Genomic Alteration: WBGene00001949(hlh-2)
Availability: unknown
Source References: PMID:37039075
Synonyms: hlh-2(bmd90[LoxP::GFP::hlh-2]) I.
Notes: GFP reporter inserted into N-terminus of endogenous hlh-2 locus. Reference: Medwig-Kinney TN, et al. Development. 2020 Jan 2;147(1).|"GFP::HLH-2 endogenous tag"|"Made_by: Taylor N. Medwig-Kinney"
Proper citation: RRID:WB-STRAIN:WBStrain00047249 Copy
http://www.wormbase.org/db/get?name=WBStrain00047260
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:33677541
Synonyms: reSi5 I.
Notes: Made_by: Tam Duong|"reSi5 [ges-1p::TIR1::F2A::mTagBFP2::AID*::NLS::tbb-2 3'UTR] (I:-5.32). Intestinal-specific expression of TIR1 co-factor for AID, and tissue-specific AID-tagged blue protein in intestinal nuclei."|"WBStrain mapped, WBPaper00061130 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00047260 Copy
http://www.wormbase.org/db/get?name=WBStrain00047263
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: reSi12 II.
Notes: Made_by: Tam Duong|"reSi12 [ges-1p::TIR1::F2A::mTagBFP2::AID*::NLS::tbb-2 3'UTR] (II:0.77). Intestinal-specific expression of TIR1 co-factor for AID, and tissue-specific AID-tagged blue protein in intestinal nuclei."
Proper citation: RRID:WB-STRAIN:WBStrain00047263 Copy
http://www.wormbase.org/db/get?name=WBStrain00047264
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: EMPTY
Synonyms: egxSi126 I; unc-119(ed3) III
Notes: egxSi126 [mex-5p::hsp-3(aa1-19)::halotag::HDEL::pie-1 3UTR + unc-119(+)] I. Superficially wild-type. Stable expression of Halotag in the ER lumen in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Xintao Fan"
Proper citation: RRID:WB-STRAIN:WBStrain00047264 Copy
http://www.wormbase.org/db/get?name=WBStrain00047255
Source Database: WormBase (WB)
Affected Genes: WBGene00000911(daf-15)
Genomic Alteration: WBGene00000911(daf-15)
Availability: unknown
Source References: EMPTY
Synonyms: daf-15(re257[daf-15::mNG::AID]) IV.
Notes: Made_by: Tam Duong|"mNeonGreen tag inserted at 3' end of endogenous daf-15 locus; AID at 3' end of mNeonGreen. Ubiquitous expression. Transgene can be degraded in a background expressing TIR1 co-factor and supplemented with auxin."
Proper citation: RRID:WB-STRAIN:WBStrain00047255 Copy
http://www.wormbase.org/db/get?name=WBStrain00047257
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:33677541, PMID:37651423, PMID:37773960, PMID:38483995
Synonyms: reSi1[col-10p::TIR1::F2A::mTagBFP2::AID*::NLS::tbb-2 3'UTR] I:-5.32
Notes: Made_by: Tam Duong|"reSi1 [col-10p::TIR1::F2A::mTagBFP2::AID*::NLS::tbb-2 3'UTR] (I:-5.32). Hypodermal-specific expression of TIR1 co-factor for AID, and tissue-specific AID-tagged blue protein in hypodermal nuclei."|"Supplementary_genotype reSi1 [col-10p::TIR1::F2A::mTagBFP2:: AID*::NLS::tbb-2 3'UTR] I"|"Supplementary_genotype reSi1[Pcol-10::TIR1::F2A::mTagBFP2::AID*::NLS::tbb-2 3'UTR]"|"WBStrain mapped, WBPaper00061130 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00047257 Copy
http://www.wormbase.org/db/get?name=WBStrain00047237
Source Database: WormBase (WB)
Affected Genes: WBGene00003514(myo-2)|WBGene00005016(sqt-1)|WBGene00045342(mir-785)
Genomic Alteration: WBGene00003514(myo-2), WBGene00005016(sqt-1), WBGene00045342(mir-785)
Availability: unknown
Source References: EMPTY
Synonyms: mir-785(umn32[lox2272 myo-2p::wrmScarlet + lox511I sqt-1(d) hsp::CRE HygR Lox511I + Lox2272]) X.
Notes: Made_by: Julie Knott & Marcus Vargas|"mir-785 pre-miRNA deletion strain deletion allele in which mir-785 pre-miRNA was replaced by myo-2p::wrmScarlet. Rollers. Generated in parental strain N2. [NOTE: Low levels of Cre activity can lead to excision of the SEC, causing the strain to lose the Roll phentoype. Pick Rollers to retain full transgene cassette.]"
Proper citation: RRID:WB-STRAIN:WBStrain00047237 Copy
http://www.wormbase.org/db/get?name=WBStrain00047239
Source Database: WormBase (WB)
Affected Genes: WBGene00003514(myo-2)|WBGene00005016(sqt-1)
Genomic Alteration: WBGene00003514(myo-2), WBGene00005016(sqt-1)
Availability: unknown
Source References: EMPTY
Synonyms: mir-356(umn42[lox2272 myo-2p::wrmScarlet + lox511I sqt-1(d) hsp::CRE HygR LoX511I + Lox2272]) III.
Notes: Made_by: Julie Knott & Marcus Vargas|"mir-356 pre-miRNA deletion strain deletion allele in which mir-356 pre-miRNA was replaced by myo-2p::wrmScarlet. Rollers. Generated in parental strain N2. [NOTE: Low levels of Cre activity can lead to excision of the SEC, causing the strain to lose the Roll phentoype. Pick Rollers to retain full transgene cassette.]"
Proper citation: RRID:WB-STRAIN:WBStrain00047239 Copy
http://www.wormbase.org/db/get?name=WBStrain00047291
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: goeEx737.
Notes: goeEx737 [flp-24p::SL1::GCaMP3.35-SL2::SL2::mKate2::unc-54 3'UTR + unc-119(+)]. ALA-specific expression of GCaMP with an additional mKate marker for expression reference. Pick mKate+ to maintain. High transmission rate (>99%). Reference: Konietzka et al. 2019. Current Biology (accepted).|"Made_by: Dr. Jan Konietzka"
Proper citation: RRID:WB-STRAIN:WBStrain00047291 Copy
http://www.wormbase.org/db/get?name=WBStrain00047293
Source Database: WormBase (WB)
Affected Genes: WBGene00003834(nxf-1)
Genomic Alteration: WBGene00003834(nxf-1)
Availability: unknown
Source References: EMPTY
Synonyms: nxf-1(t2160) V.
Notes: Made_by: Angelina Zheleva, Juan Cabello, Ralf Schnabel|"Temperature-sensitive. Maintain at 15-20C. 100% embryonic lethal at 25C. Pharynx unattached (Pun) and morphogenic defects. Reference: Zheleva A, et al. PLoS Genet. 2019 Sep 16;15(9):e1008338."
Proper citation: RRID:WB-STRAIN:WBStrain00047293 Copy
http://www.wormbase.org/db/get?name=WBStrain00047294
Source Database: WormBase (WB)
Affected Genes: WBGene00003834(nxf-1)
Genomic Alteration: WBGene00003834(nxf-1)
Availability: unknown
Source References: PMID:37254647
Synonyms: nxf-1(t2160) V; jcpEx6.
Notes: jcpEx6 [nxf-1p::nxf-1::3xFLAG::eGFP::nxf-1UTR]. jcpEx6 transgene rescues nxf-1(t2160) embryonic lethality at 25C. Temperature-sensitive; maintain at 25C to retain the array. nxf-1(t2160) mutants are 100% embryonic lethal at 25C. Reference: Zheleva A, et al. PLoS Genet. 2019 Sep 16;15(9):e1008338.
Proper citation: RRID:WB-STRAIN:WBStrain00047294 Copy
http://www.wormbase.org/db/get?name=WBStrain00047295
Source Database: WormBase (WB)
Affected Genes: WBGene00003930(pat-3)
Genomic Alteration: WBGene00003930(pat-3)
Availability: unknown
Source References: EMPTY
Synonyms: pat-3(st564) III; mwEx32.
Notes: mwEx32 [pat-3(YYFF) + sur-5::GFP]. Pick GFP+ to maintain. mwEx32 carries a mutant form of pat-3 gene with tyrosine (Y) to phenylalanine (F) mutations; rescues pat-3 null allele. Abnormal DTC migration. Reference: Lee M, et al. J Biol Chem. 2001 Sep 28;276(39):36404-10.
Proper citation: RRID:WB-STRAIN:WBStrain00047295 Copy
http://www.wormbase.org/db/get?name=WBStrain00047296
Source Database: WormBase (WB)
Affected Genes: WBGene00003930(pat-3)
Genomic Alteration: WBGene00003930(pat-3)
Availability: unknown
Source References: EMPTY
Synonyms: pat-3(st564) III; mwEx443.
Notes: mwEx443 [pat-3(+) + sur-5::GFP]. Pick GFP+ to maintain. mwEx443 contains wild type contains pat-3 genomic DNA, rescues pat-3 null allele. Reference: Lee M, et al. J Biol Chem. 2001 Sep 28;276(39):36404-10.
Proper citation: RRID:WB-STRAIN:WBStrain00047296 Copy
http://www.wormbase.org/db/get?name=WBStrain00047330
Source Database: WormBase (WB)
Affected Genes: WBGene00022257(puf-11)
Genomic Alteration: WBGene00022257(puf-11)
Availability: unknown
Source References: EMPTY
Synonyms: puf-11(q971) IV.
Notes: Made_by: Kim Haupt|"Superficially wild-type."
Proper citation: RRID:WB-STRAIN:WBStrain00047330 Copy
http://www.wormbase.org/db/get?name=WBStrain00047287
Source Database: WormBase (WB)
Affected Genes: WBGene00016173(fust-1)
Genomic Alteration: WBGene00016173(fust-1)
Availability: unknown
Source References: EMPTY
Synonyms: fust-1(rt255) II.
Notes: Made_by: Saba Baskoylu|"Superficially wild-type. This is the appropriate control strain for FUS disease models HA2846 and HA2847. This control strain contains presumably silent edits inserted by CRISPR editing while creating the FUS disease models in HA2846 and HA2847, and was back-crossed to remove the pha-1 allele used in strain construction. Reference: Baskoylu S, et al. bioRxiv 799932; doi: https:"
Proper citation: RRID:WB-STRAIN:WBStrain00047287 Copy
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