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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040744
Source Database: WormBase (WB)
Affected Genes: WBGene00018636(oef-1)
Genomic Alteration: WBGene00018636(oef-1)
Availability: available
Source References: EMPTY
Synonyms: oef-1(vr25) IV.
Alternate IDs: WB-STRAIN:YL585, CGC_YL585
Notes: Made_by: Catherine McManus|"vr25 is a Crispr/Cas9-induced 56 bp deletion in exon 2 of oef-1/F49E8.2 causing a frameshift and presumptive null allele. Accelerated rate of germ cell progression, precocious Z2/Z3 division in L1s, increased brood size and sperm generation, and increased germline apoptosis. Reference: McManus, CE & Reinke, V. Genetics. 2017; https:"
Proper citation: RRID:WB-STRAIN:WBStrain00040744 Copy
http://www.wormbase.org/db/get?name=WBStrain00040745
Source Database: WormBase (WB)
Affected Genes: WBGene00002783(let-607)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00002783(let-607), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: let-607(tm1423) I; unc-119(ed3) III; vrIs121.
Alternate IDs: WB-STRAIN:YL651, CGC_YL651
Notes: vrIs121 [let-607(fosmid)::GFP + unc-119(+)]. let-607 locus in fosmid tagged at the carboxy-terminus with GFP. Derived by crossing the LET-607::GFP transgenic strain (YL529) to let-607(tm1423) mutants. vrIs121 transgene rescues the lethal mutant phenotype of let-607(tm1423) homozygous mutants. Reference: Weicksel SE, et al. Development. 2016 Oct 1;143(19):3540-3548.
Proper citation: RRID:WB-STRAIN:WBStrain00040745 Copy
http://www.wormbase.org/db/get?name=WBStrain00040742
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; vrIs83.
Alternate IDs: WB-STRAIN:YL448, CGC_YL448
Notes: Made_by: Reinke Lab|"Modern strain"|"vrIs83 [ges-1p::dpl-1::GFP::FLAG::dpl-1 3'UTR + unc-119(+)]."
Proper citation: RRID:WB-STRAIN:WBStrain00040742 Copy
http://www.wormbase.org/db/get?name=WBStrain00040718
Source Database: WormBase (WB)
Affected Genes: WBGene00000235(baf-1)|WBGene00000254(bli-4)|WBGene00001578(ges-1)|WBGene00002246(lag-2)|WBGene00003514(myo-2)|WBGene00003983(pes-10)
Genomic Alteration: WBGene00000235(baf-1), WBGene00000254(bli-4), WBGene00001578(ges-1), WBGene00002246(lag-2), WBGene00003514(myo-2), WBGene00003983(pes-10)
Availability: available
Source References: EMPTY
Synonyms: baf-1(gk324) III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); qIs19 V.
Alternate IDs: WB-STRAIN:YG1011, CGC_YG1011
Notes: qIs19 [lag-2p::GFP::unc-54 3'UTR + rol-6(su1006)] V. Heterozygotes are Rollers with pharyngeal GFP signal, and segregate arrested hT2 aneuploids, and non-GFP gk324 homozygotes (Sterile and Unc). All worms express lag-2p::GFP at the distal tip cells. qIs48 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and a gut promoter driving GFP in the intestine, and is homozygous lethal.
Proper citation: RRID:WB-STRAIN:WBStrain00040718 Copy
http://www.wormbase.org/db/get?name=WBStrain00040715
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00016151(smc-5)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00016151(smc-5)
Availability: available
Source References: EMPTY
Synonyms: smc-5(tm2868)/mIn1 [mIs14 dpy-10(e128)] II.
Alternate IDs: WB-STRAIN:YE59, CGC_YE59
Notes: Homozygous viable mutation balanced by GFP- and dpy-10-marked inversion. Heterozygotes are WT with relatively dim pharyngeal GFP signal, and segregate WT dim GFP, Dpy bright GFP (mIn1 homozygotes), and non-GFP tm2868 homozygotes. Pick WT dim GFP and check for correct segregation of progeny to maintain. tm2868 homozygotes are morphologically wild-type but show ~30% reduction in fertilized eggs and a trans-generational increase in sterility. Maintain under normal conditions. Reference: Bickel JS, et al. PLoS Genet. 2010 Jul 22;6(7):e1001028.|"Made_by: Jeremy Bickel"
Proper citation: RRID:WB-STRAIN:WBStrain00040715 Copy
http://www.wormbase.org/db/get?name=WBStrain00040714
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00010056(smc-6)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00010056(smc-6)
Availability: available
Source References: PMID:39115289
Synonyms: smc-6(ok3294)/mIn1 [mIs14 dpy-10(e128)] II.
Alternate IDs: WB-STRAIN:YE58, CGC_YE58
Notes: Homozygous viable mutation balanced by GFP- and dpy-10-marked inversion. Heterozygotes are WT with relatively dim pharyngeal GFP signal, and segregate WT dim GFP, Dpy bright GFP (mIn1 homozygotes), and non-GFP ok3294 homozygotes. Pick WT dim GFP and check for correct segregation of progeny to maintain. ok3294 homozygotes are morphologically wild-type but show ~30% reduction in fertilized eggs and a trans-generational increase in sterility. Maintain under normal conditions. Reference: Bickel JS, et al. PLoS Genet. 2010 Jul 22;6(7):e1001028.|"Made_by: Jeremy Bickel"
Proper citation: RRID:WB-STRAIN:WBStrain00040714 Copy
http://www.wormbase.org/db/get?name=WBStrain00040716
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: ([baf-1p::GFP::lmn-1 L535P unc-119(+)]; unc-119 (ed3))
Alternate IDs: WB-STRAIN:YG499
Notes: Created as part of the paper markup
Proper citation: RRID:WB-STRAIN:WBStrain00040716 Copy
http://www.wormbase.org/db/get?name=WBStrain00040793
Source Database: WormBase (WB)
Affected Genes: WBGene00001620(glt-1)|WBGene00001621(glt-3)
Genomic Alteration: WBGene00001620(glt-1), WBGene00001621(glt-3)
Availability: available
Source References: PMID:31306683
Synonyms: glt-3(bz34) IV; glt-1(ok206) X.
Alternate IDs: WB-STRAIN:ZB1106, CGC_ZB1106
Notes: Reference: Mano et al. (2007) J Biol Chem 282(47):34412-9.
Proper citation: RRID:WB-STRAIN:WBStrain00040793 Copy
http://www.wormbase.org/db/get?name=WBStrain00040792
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZB1105
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040792 Copy
http://www.wormbase.org/db/get?name=WBStrain00040710
Source Database: WormBase (WB)
Availability: available
Source References: PMID:33976151
Synonyms: ypIn2 II.
Alternate IDs: WB-STRAIN:YA1197, CGC_YA1197
Notes: ypIn2 [daz-1p::pot-1::mCherry::tbb-2 3'UTR + Cbr-unc-119(+)] II. Single copy MosSCI insertion at ttTi5605 locus on LG II. Reference: Shtessel L, et al. G3 (Bethesda). 2013 Feb;3(2):305-13.
Proper citation: RRID:WB-STRAIN:WBStrain00040710 Copy
http://www.wormbase.org/db/get?name=WBStrain00040798
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZB1336
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040798 Copy
http://www.wormbase.org/db/get?name=WBStrain00040712
Source Database: WormBase (WB)
Affected Genes: WBGene00007395(dcar-1)
Genomic Alteration: WBGene00007395(dcar-1)
Availability: available
Source References: EMPTY
Synonyms: dcar-1(tm2484) V.
Alternate IDs: WB-STRAIN:YC307, CGC_YC307
Notes: Defective avoidance to water-soluble repellent. Reference: Aoki R., et al. J Neurosci. 2011 Nov 16;31(46):16603-10.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00040712 Copy
http://www.wormbase.org/db/get?name=WBStrain00040797
Source Database: WormBase (WB)
Affected Genes: WBGene00001612(glr-1)|WBGene00001613(glr-2)|WBGene00001621(glt-3)
Genomic Alteration: WBGene00001612(glr-1), WBGene00001613(glr-2), WBGene00001621(glt-3)
Availability: unknown
Source References: EMPTY
Synonyms: glr-2(ak10) glr-1(ky176) III; glt-3(bz34) IV; nuIs5 V.
Alternate IDs: WB-STRAIN:ZB1335
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040797 Copy
http://www.wormbase.org/db/get?name=WBStrain00040729
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00003821(nst-1)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00003821(nst-1)
Availability: available
Source References: EMPTY
Synonyms: nst-1(vr6)/mIn1 [mIs14 dpy-10(e128)] II.
Alternate IDs: WB-STRAIN:YL108, CGC_YL108
Notes: mIn1 carries a GFP marker. Heterozygotes are GFP+ and segregate heterozygotes (wild-type GFP+), mIn1 homozygotes (Dpy GFP+) and vr6 homozygotes (GFP- and arrest as L1/L2 larvae). Maintain by picking GFP+ and checking for proper segregation of progeny. Reference: Kudron et al. (2008) PLos Genet 4(8):e1000181.
Proper citation: RRID:WB-STRAIN:WBStrain00040729 Copy
http://www.wormbase.org/db/get?name=WBStrain00040728
Source Database: WormBase (WB)
Affected Genes: WBGene00000272(bro-1)
Genomic Alteration: WBGene00000272(bro-1)
Availability: unknown
Source References: EMPTY
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:YK149
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040728 Copy
http://www.wormbase.org/db/get?name=WBStrain00040722
Source Database: WormBase (WB)
Affected Genes: WBGene00000235(baf-1)|WBGene00000254(bli-4)|WBGene00001159(eff-1)
Genomic Alteration: WBGene00000235(baf-1), WBGene00000254(bli-4), WBGene00001159(eff-1)
Availability: available
Source References: EMPTY
Synonyms: baf-1(gk324) III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); eff-1(ok1021) II; syIs78.
Alternate IDs: WB-STRAIN:YG1046, CGC_YG1046
Notes: syIs78 [ajm-1::GFP + unc-119(+)] is probably on LG I (not on II, III, V or X). Heterozygotes are slow-growing DpyUnc with cell fusion problems and pharyngeal GFP signal. Segregates arrested hT2 aneuploids, and non-GFP DpyUnc gk324 homozygotes (Sterile, Dpy and Unc). All worms express ajm-1::GFP(Junction Associated Protein). qIs48 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and a gut promoter driving GFP in the intestine, and is homozygous lethal.
Proper citation: RRID:WB-STRAIN:WBStrain00040722 Copy
http://www.wormbase.org/db/get?name=WBStrain00040724
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00000386(cdc-25.1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00000386(cdc-25.1)
Availability: available
Source References: EMPTY
Synonyms: cdc-25.1(bn115) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:YHS2, CGC_YHS2
Notes: Homozygous sterile deletion balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP bn115 homozygotes (sterile). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Kim J, et al. (2009) Mol Cell 28:43-8.
Proper citation: RRID:WB-STRAIN:WBStrain00040724 Copy
http://www.wormbase.org/db/get?name=WBStrain00040723
Source Database: WormBase (WB)
Affected Genes: WBGene00012132(ifta-2)
Genomic Alteration: WBGene00012132(ifta-2)
Availability: available
Source References: PMID:38302462
Synonyms: ifta-2(tm1724) IV.
Alternate IDs: WB-STRAIN:YH461, CGC_YH461
Notes: Extended life span. daf-d.
Proper citation: RRID:WB-STRAIN:WBStrain00040723 Copy
http://www.wormbase.org/db/get?name=WBStrain00040720
Source Database: WormBase (WB)
Affected Genes: WBGene00000235(baf-1)|WBGene00000254(bli-4)|WBGene00001578(ges-1)|WBGene00003052(lmn-1)|WBGene00003514(myo-2)|WBGene00003983(pes-10)
Genomic Alteration: WBGene00000235(baf-1), WBGene00000254(bli-4), WBGene00001578(ges-1), WBGene00003052(lmn-1), WBGene00003514(myo-2), WBGene00003983(pes-10)
Availability: available
Source References: EMPTY
Synonyms: baf-1(gk324) III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); ccIs4810 X.
Alternate IDs: WB-STRAIN:YG1021, CGC_YG1021
Notes: ccIs4810 [(pJKL380.4) lmn-1p::lmn-1::GFP::lmn-1 3'utr + (pMH86) dpy-20(+)] X. Heterozygotes are WT with pharyngeal GFP signal, and segregate arrested hT2 aneuploids, non-GFP gk324 homozygotes (Sterile and Unc). All worms express Cel-lamin::GFP (lmn-1 gene is expressed at the nuclear periphery). qIs48 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and a gut promoter driving GFP in the intestine, and is homozygous lethal.
Proper citation: RRID:WB-STRAIN:WBStrain00040720 Copy
http://www.wormbase.org/db/get?name=WBStrain00040770
Source Database: WormBase (WB)
Affected Genes: WBGene00014208(znfx-1)
Genomic Alteration: WBGene00014208(znfx-1)
Availability: available
Source References: PMID:37878696
Synonyms: znfx-1(gg561) II.
Alternate IDs: WB-STRAIN:YY996, CGC_YY996
Notes: Heritable RNAi defective, germline immortality. Reference: Wan G, et al. Nature. 2018 May;557(7707):679-683.|"Supplementary_genotype znfx-1(gg561)"
Proper citation: RRID:WB-STRAIN:WBStrain00040770 Copy
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The data sets included in this resource are published in Kravitz et al, 2012. Distinct roles for direct and indirect pathway striatal neurons in reinforcement (Nat. Neurosci).
