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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040312
Source Database: WormBase (WB)
Affected Genes: WBGene00014028(trxr-2)|WBGene00015553(trxr-1)
Genomic Alteration: WBGene00014028(trxr-2), WBGene00015553(trxr-1)
Availability: available
Source References: EMPTY
Synonyms: trxr-2(tm2047) III; trxr-1(sv47) IV.
Alternate IDs: WB-STRAIN:VZ14, CGC_VZ14
Notes: Made_by: B. Cacho Valadez|"sv47 deletion removes bases 721-2383 of the trxr-1 genomic sequence (as measured from the start of the trxr-1 coding sequence). tm2047 removes bases -128 to +380 relative to the start of the trxr-2 coding sequence (removing part of the proximal promoter). tm2047 outcrossed 6x. sv47 outcrossed 10x. Reference: Cacho-Valadez B, et al. Antioxid Redox Signal. 2012 Jun 15;16(12):1384-400."
Proper citation: RRID:WB-STRAIN:WBStrain00040312 Copy
http://www.wormbase.org/db/get?name=WBStrain00040325
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: vzEx60.
Alternate IDs: WB-STRAIN:VZ184, CGC_VZ184
Notes: Made_by: F Muoz Lobato|"vzEx60 [dnj-27p(2kb)::dnj-27::YFP::KDEL]. Superficially wild-type. Pick YFP+ to maintain. Fluorescence should be easily detected under a dissection scope if present, but array has low transmission rate. Reference: Muoz-Lobato F, et al. Antioxid Redox Signal. 2014 Jan 10; 20(2): 217-235."|"vzEx60 [dnj-27p(2kb)::dnj-27::YFP::KDEL]. Superficially wild-type. Pick YFP+ to maintain. Reference: Muoz-Lobato F, et al. Antioxid Redox Signal. 2014 Jan 10; 20(2): 217-235."
Proper citation: RRID:WB-STRAIN:WBStrain00040325 Copy
http://www.wormbase.org/db/get?name=WBStrain00040328
Source Database: WormBase (WB)
Affected Genes: WBGene00001078(dpy-19)|WBGene00001609(glp-1)|WBGene00008117(gsr-1)
Genomic Alteration: WBGene00001078(dpy-19), WBGene00001609(glp-1), WBGene00008117(gsr-1)
Availability: available
Source References: EMPTY
Synonyms: gsr-1(tm3574)/qC1 dpy-19(e1259) glp-1(q339) nIs281 III.
Alternate IDs: WB-STRAIN:VZ454, CGC_VZ454
Notes: Made_by: Francisco Jos Naranjo-Galindo|"nIs281 [myo-2::RFP] integrated near qC1. Recombination between nIs281 and qC1 has been reported. Fails to complemement all markers on qC1. Heterozygotes are WT and segregate WT, Dpy Sterile, and tm3574 homozygotes. gsr-1(tm3574) is embryonic lethal. gsr-1(m+,z-) animals are viable and reach adulthood with no visible phenotype and lay eggs that invariably arrest at the pregastrula stage; they are slightly short-lived, have increased mitochondrial fragmentation, decreased mitochondrial DNA content and have induced mitochondrial UPR measured by hsp-6::GFP levels. gsr-1(m-,z-) have aberrant perinuclear distribution of interphasic chromatin. NOTE: The RFP-labeled balancer is reportedly not entirely stable in this strain and will occasionally segregate recombinants of two types: sterile RFP+ animals (most likely homozygous qC1 [nIs281] worms that are able to grow to adulthood but do not develop germline), and non-RFP animals that lay viable progeny. Maintain by picking fertile RFP+ animals and confirming that non-RFP progeny lay 100% arrested embryos. Reference: Mora-Lorca JA, et al. Free Radic Biol Med. 2016 Jul;96:446-61."
Proper citation: RRID:WB-STRAIN:WBStrain00040328 Copy
http://www.wormbase.org/db/get?name=WBStrain00040322
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: vzEx32.
Alternate IDs: WB-STRAIN:VZ119, CGC_VZ119
Notes: vzEx32 [(pVZ35) trx-3p::GFP + (pRF4) rol-6(su1006)]. Rollers. Pick Rollers to maintain. GFP expression in intestine. Reference: Jimnez-Hidalgo M, et al. Free Radic Biol Med. (2014) 68:205-219.|"vzEx32 [trx-3p::GFP + rol-6(su1006)]. Rollers. Pick Rollers to maintain. GFP expression in intestine. Reference: Jimnez-Hidalgo M, et al. Free Radic Biol Med. (2014) 68:205-219."
Proper citation: RRID:WB-STRAIN:WBStrain00040322 Copy
http://www.wormbase.org/db/get?name=WBStrain00040324
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: vzEx41.
Alternate IDs: WB-STRAIN:VZ149, CGC_VZ149
Notes: Made_by: F Muoz Lobato|"vzEx41 [dnj-27p(2kb)::dnj-27::dnj-27 3'UTR + unc-122p::GFP]. Superficially wild-type. Pick GFP+ to maintain. Reference: Muoz-Lobato F, et al. Antioxid Redox Signal. 2014 Jan 10; 20(2): 217-235."
Proper citation: RRID:WB-STRAIN:WBStrain00040324 Copy
http://www.wormbase.org/db/get?name=WBStrain00040372
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00004775(sep-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00004775(sep-1)
Availability: available
Source References: PMID:32273538
Synonyms: sep-1(e2406) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:WH216, CGC_WH216
Notes: Heterozygotes have myo-2::GFP [qIs48] strongly expressed in the pharynx and are viable at 25C. 100% of sep-1 homozygotes are strongly Sterile Unc at 25C (at 20C, 100% are Sterile but no so Unc). Up to 30% of the homozygotes are Sterile at 16C. hT2[qIs48] homozygotes are dead. Note: qIs48 has been observed to recombine off hT2, typically leaving behind a functional homozygous viable hT2 with Bli-4 phenotype.|"Reference WBPaper00059538 added based on published strain data identified by Textpresso literature search."
Proper citation: RRID:WB-STRAIN:WBStrain00040372 Copy
http://www.wormbase.org/db/get?name=WBStrain00040370
Source Database: WormBase (WB)
Affected Genes: WBGene00006795(unc-61)
Genomic Alteration: WBGene00006795(unc-61)
Availability: available
Source References: EMPTY
Synonyms: unc-61(n3169) V.
Alternate IDs: WB-STRAIN:WH202, CGC_WH202
Notes: Poor backward movement. Protrusive vulva. Gonad extrusion. Egg-laying defects. Recessive.
Proper citation: RRID:WB-STRAIN:WBStrain00040370 Copy
http://www.wormbase.org/db/get?name=WBStrain00040377
Source Database: WormBase (WB)
Affected Genes: WBGene00001018(dnc-2)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00001018(dnc-2), WBGene00006843(unc-119)
Availability: available
Source References: PMID:37684042
Synonyms: unc-119(ed3) III; ojIs57.
Alternate IDs: WB-STRAIN:WH258, CGC_WH258
Notes: ojIs57 [pie-1::GFP::dnc-2 + unc-119(+)]|"Supplementary_genotype unc-119(ed3) III; ojIs5"
Proper citation: RRID:WB-STRAIN:WBStrain00040377 Copy
http://www.wormbase.org/db/get?name=WBStrain00040378
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00013168(arp-1)
Genomic Alteration: WBGene00006843(unc-119), WBGene00013168(arp-1)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; ojIs47.
Alternate IDs: WB-STRAIN:WH259, CGC_WH259
Notes: ojIs47 [arp-1::GFP + unc-119(+)].
Proper citation: RRID:WB-STRAIN:WBStrain00040378 Copy
http://www.wormbase.org/db/get?name=WBStrain00040308
Source Database: WormBase (WB)
Affected Genes: WBGene00013164(Y53F4B.18)
Genomic Alteration: WBGene00013164(Y53F4B.18)
Availability: available
Source References: EMPTY
Synonyms: Y53F4B.18(vq3) II.
Alternate IDs: WB-STRAIN:VV213, CGC_VV213
Notes: Made_by: Alan To|"Superficially wild-type. Reference: Chen AL, et al. Nat Chem Biol. 2019 Mar 25. doi: 10.1038/s41589-019-0243-4."
Proper citation: RRID:WB-STRAIN:WBStrain00040308 Copy
http://www.wormbase.org/db/get?name=WBStrain00040309
Source Database: WormBase (WB)
Affected Genes: WBGene00015062(trx-1)
Genomic Alteration: WBGene00015062(trx-1)
Availability: available
Source References: PMID:37258276, PMID:38446031
Synonyms: trx-1(ok1449) II.
Alternate IDs: WB-STRAIN:VZ1, CGC_VZ1
Notes: B0228.5 Homozygous. Exhibits slightly shortened lifespan compared to wild-type. Outer Left Sequence: cgccgtggttaacctcttta. Outer Right Sequence: ttatcggacaataggcggac. Inner Left Sequence: ctgttgactcccaacaccct. Inner Right Sequence: ttgcaaaagaaattttcgcc. Inner Primer PCR Length: 2357. Estimated Deletion Size: about 850 bp. This strain was provided by the C. elegans Gene Knockout Project at OMRF, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. URL: www.mutantfactory.ouhsc.edu/ Reference: Miranda-Vizuete A, et al. FEBS Lett. 2006 Jan 23;580(2):484-90.|"Made_by: A. Miranda Vizuete"|"Supplementary_genotype trx-1(ok1449)"
Proper citation: RRID:WB-STRAIN:WBStrain00040309 Copy
http://www.wormbase.org/db/get?name=WBStrain00040383
Source Database: WormBase (WB)
Affected Genes: WBGene00004027(pie-1)|WBGene00006843(unc-119)|WBGene00016395(spcs-1)
Genomic Alteration: WBGene00004027(pie-1), WBGene00006843(unc-119), WBGene00016395(spcs-1)
Availability: available
Source References: PMID:30489010, PMID:37684042, PMID:39167497
Synonyms: unc-119(ed3) III; ojIs23.
Alternate IDs: WB-STRAIN:WH327, CGC_WH327
Notes: ojIs23 [pie-1p::GFP::C34B2.10].|"Reference WBPaper00055815 added based on published strain data identified by Textpresso literature search."|"Supplementary_genotype unc-119(ed3) III; ojIs23 [Ppie-1GFP::SP12]"
Proper citation: RRID:WB-STRAIN:WBStrain00040383 Copy
http://www.wormbase.org/db/get?name=WBStrain00040386
Source Database: WormBase (WB)
Affected Genes: WBGene00004274(rab-11.1)
Genomic Alteration: WBGene00004274(rab-11.1)
Availability: unknown
Source References: EMPTY
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:WH0347
Notes: Retired following removal of zero padded strain public_names.
Proper citation: RRID:WB-STRAIN:WBStrain00040386 Copy
http://www.wormbase.org/db/get?name=WBStrain00040380
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; ojIs12.
Alternate IDs: WB-STRAIN:WH279, CGC_WH279
Notes: ojIs12 [cyk-4::GFP + unc-119(+)]. Strain is not very healthy. Described as integratred array but appears to segregate Uncs. Maintain at 15-20C.
Proper citation: RRID:WB-STRAIN:WBStrain00040380 Copy
http://www.wormbase.org/db/get?name=WBStrain00040304
Source Database: WormBase (WB)
Affected Genes: WBGene00045328(mir-794)|WBGene00045329(mir-795)
Genomic Alteration: WBGene00045328(mir-794), WBGene00045329(mir-795)
Availability: available
Source References: EMPTY
Synonyms: mir-794 mir-795(maDf5) I.
Alternate IDs: WB-STRAIN:VT3301, CGC_VT3301
Notes: mir-794 mir-795(maDf5) enhances retarded phenotypes of mir-48 mir-241 (nDF51). maDf5 allele is missing the 1312 nucleotide region between ATACATATTCCGAGAAACGTTACCT and GTGAGGCGCCAAATGCCGGCCTCAC [chrI:12,594,556-12,595,917 of WBcel235/ce11].
Proper citation: RRID:WB-STRAIN:WBStrain00040304 Copy
http://www.wormbase.org/db/get?name=WBStrain00040303
Source Database: WormBase (WB)
Affected Genes: WBGene00045329(mir-795)
Genomic Alteration: WBGene00045329(mir-795)
Availability: available
Source References: EMPTY
Synonyms: mir-795(ma298) I; maIs105 V.
Alternate IDs: WB-STRAIN:VT3299, CGC_VT3299
Notes: maIs105 [col-19::GFP] V. mir-795(ma298) enhances retarded phenotypes of mir-48 mir-241 (nDF51). ma298 allele is missing the 5 nucleotides between CCGAGAAACGTTACCTGCT and AGATTGATCAGCGAGCTTGA [chrI:12,594,565-12,594,608 of WBcel235/ce11].
Proper citation: RRID:WB-STRAIN:WBStrain00040303 Copy
http://www.wormbase.org/db/get?name=WBStrain00040306
Source Database: WormBase (WB)
Affected Genes: WBGene00004780(ser-7)
Genomic Alteration: WBGene00004780(ser-7)
Availability: available
Source References: EMPTY
Synonyms: ser-7(vq2) X.
Alternate IDs: WB-STRAIN:VV207, CGC_VV207
Notes: CRISPR/Cas9-engineered knockout of ser-7. Resistant to exogenous serotonin induced food intake. Reference: Perez-Gomez A., et al. Nat Commun. 2018 Dec 10;9(1):5272.|"Made_by: Alan To"
Proper citation: RRID:WB-STRAIN:WBStrain00040306 Copy
http://www.wormbase.org/db/get?name=WBStrain00040305
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00001842(her-1)|WBGene00003598(nhl-2)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00001842(her-1), WBGene00003598(nhl-2)
Availability: unknown
Source References: EMPTY
Synonyms: nDf50/mIn1 [mIs14 dpy-10(e128)] II; nhl-2(ok818) III; her-1(n695) V.
Alternate IDs: WB-STRAIN:VT3363
Notes: Pick wild-type GFP+ to maintain. Heterozygotes are WT with GFP+ pharynx, and segregate Dpy GFP+ mIn1 homozygotes, and GFP- low viability non-Egl hermaphrodites. Viability of first generation nDf50 homozygotes (GFP-) segregated from balanced heterozygotes is rescued by maternal contribution of mir-35-41 from balancer. Second generation GFP- animals are low viability. Reference: McJunkin K, Ambros V. Genes Dev. 2017 Feb 15;31(4):422-437.
Proper citation: RRID:WB-STRAIN:WBStrain00040305 Copy
http://www.wormbase.org/db/get?name=WBStrain00040388
Source Database: WormBase (WB)
Affected Genes: WBGene00004027(pie-1)
Genomic Alteration: WBGene00004027(pie-1)
Availability: unknown
Source References: EMPTY
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:WH0351
Notes: Retired following removal of zero padded strain public_names.
Proper citation: RRID:WB-STRAIN:WBStrain00040388 Copy
http://www.wormbase.org/db/get?name=WBStrain00040387
Source Database: WormBase (WB)
Affected Genes: WBGene00004274(rab-11.1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004274(rab-11.1), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; ojIs35.
Alternate IDs: WB-STRAIN:WH347, CGC_WH347
Notes: Made_by: Jane Squirrell|"ojIs35 [pie-1::GFP::rab-11.1 + unc-119(+)]."
Proper citation: RRID:WB-STRAIN:WBStrain00040387 Copy
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