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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
https://www.jax.org/strain/000483
Source Database: JAX Mice and Services
Affected Genes: accelerated autoimmunity and lymphoproliferation transposition
Genomic Alteration: accelerated autoimmunity and lymphoproliferation
Availability: embryo
Notes: gene symbol note: accelerated autoimmunity and lymphoproliferation transposition; mutant strain|congenic strain: Yaa
Proper citation: RRID:IMSR_JAX:000483 Copy
Issue
https://www.jax.org/strain/019104
Source Database: JAX Mice and Services
Affected Genes: Kras proto-oncogene; GTPase
Genomic Alteration: targeted mutation 4; Tyler Jacks
Availability: sperm
Notes: gene symbol note: Kras proto-oncogene; GTPase; mutant strain|congenic strain: Kras
Proper citation: RRID:IMSR_JAX:019104 Copy
Issue
https://www.jax.org/strain/018963
Source Database: JAX Mice and Services
Affected Genes: |villin 1|transgene insertion 997; Deborah L Gumucio
Genomic Alteration: transgene insertion 997; Deborah L Gumucio
Availability: sperm
Synonyms: B6N.Cg-Tg(Vil-cre)997Gum/J
Notes: gene symbol note: |villin 1|transgene insertion 997; Deborah L Gumucio; mutant strain|congenic strain: |Vil1|Tg(Vil1-cre)997Gum
Proper citation: RRID:IMSR_JAX:018963 Copy
Issue
https://www.jax.org/strain/018907
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 55; Hidde Ploegh|transgene insertion; Jeffrey S Chamberlain|beta-2 microglobulin|beta-2-microglobulin|major histocompatibility complex; class I; B
Genomic Alteration: transgene insertion 55; Hidde Ploegh|transgene insertion; Jeffrey S Chamberlain|targeted mutation 1; University of North Carolina
Availability: sperm
Notes: gene symbol note: transgene insertion 55; Hidde Ploegh|transgene insertion; Jeffrey S Chamberlain|beta-2 microglobulin|beta-2-microglobulin|major histocompatibility complex; class I; B; mutant strain|congenic strain: Tg(B2M)55Hpl|Tg(HLA-B*0702)#Chmb|B2m|B2M|HLA-B
Proper citation: RRID:IMSR_JAX:018907 Copy
Issue
https://www.jax.org/strain/021456
Source Database: JAX Mice and Services
Affected Genes: accelerated autoimmunity and lymphoproliferation transposition|CD8 subunit alpha
Genomic Alteration: accelerated autoimmunity and lymphoproliferation|targeted mutation 1; Tak Mak
Availability: embryo
Notes: gene symbol note: accelerated autoimmunity and lymphoproliferation transposition|CD8 subunit alpha; mutant strain|congenic strain: Yaa|Cd8a
Proper citation: RRID:IMSR_JAX:021456 Copy
Issue
https://www.jax.org/strain/021455
Source Database: JAX Mice and Services
Affected Genes: Fc fragment of IgG receptor and transporter|accelerated autoimmunity and lymphoproliferation transposition
Genomic Alteration: targeted mutation 1; Derry C Roopenian|accelerated autoimmunity and lymphoproliferation
Availability: embryo
Notes: gene symbol note: Fc fragment of IgG receptor and transporter|accelerated autoimmunity and lymphoproliferation transposition; mutant strain|congenic strain: Fcgrt|Yaa
Proper citation: RRID:IMSR_JAX:021455 Copy
Issue
https://www.jax.org/strain/021569
Source Database: JAX Mice and Services
Affected Genes: accelerated autoimmunity and lymphoproliferation transposition|systemic lupus erythmatosus susceptibility 1
Genomic Alteration: accelerated autoimmunity and lymphoproliferation|NZM2410/Aeg
Availability: sperm
Notes: gene symbol note: accelerated autoimmunity and lymphoproliferation transposition|systemic lupus erythmatosus susceptibility 1; mutant strain|congenic strain: Yaa|Sle1
Proper citation: RRID:IMSR_JAX:021569 Copy
Issue
https://www.jax.org/strain/021565
Source Database: JAX Mice and Services
Affected Genes: CD1 antigen complex|accelerated autoimmunity and lymphoproliferation transposition
Genomic Alteration: targeted mutation 1; Michael Grusby|accelerated autoimmunity and lymphoproliferation
Availability: embryo
Synonyms: BXSB.Yaa CD1-/-. BXSB-Cd1-/-. BXSB.Yaa Cd1d1/Cd1d2-/-. CD1-deficient BXSB.Yaa
Notes: gene symbol note: CD1 antigen complex|accelerated autoimmunity and lymphoproliferation transposition; mutant strain|congenic strain: Cd1|Yaa
Proper citation: RRID:IMSR_JAX:021565 Copy
Issue Issue
https://www.jax.org/strain/021873
Source Database: JAX Mice and Services
Affected Genes: interleukin 6
Genomic Alteration: targeted mutation 1; Manfred Kopf
Availability: embryo
Synonyms: BXSB.129S6(B6)-Il6
Notes: gene symbol note: interleukin 6; mutant strain|congenic strain: Il6
Proper citation: RRID:IMSR_JAX:021873 Copy
Issue
https://www.jax.org/strain/022350
Source Database: JAX Mice and Services
Affected Genes: nitric oxide synthase 2; inducible|Fas cell surface death receptor
Genomic Alteration: targeted mutation 1; Victor E Laubach|lymphoproliferation
Availability: sperm
Notes: gene symbol note: nitric oxide synthase 2; inducible|Fas cell surface death receptor; mutant strain|congenic strain: Nos2|Fas
Proper citation: RRID:IMSR_JAX:022350 Copy
Issue
https://www.jax.org/strain/023807
Source Database: JAX Mice and Services
Affected Genes: notch 3
Genomic Alteration: targeted mutation 1; Tom Gridley
Availability: sperm
Synonyms: FVB.129S1(B6)-Notch3
Notes: gene symbol note: notch 3; mutant stock: Notch3
Proper citation: RRID:IMSR_JAX:023807 Copy
Issue
https://www.jax.org/strain/025099
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 99; Derry C Roopenian|Fc fragment of IgG receptor and transporter|accelerated autoimmunity and lymphoproliferation transposition
Genomic Alteration: transgene insertion 99; Derry C Roopenian|targeted mutation 1; Derry C Roopenian|accelerated autoimmunity and lymphoproliferation
Availability: embryo
Notes: gene symbol note: transgene insertion 99; Derry C Roopenian|Fc fragment of IgG receptor and transporter|accelerated autoimmunity and lymphoproliferation transposition; mutant strain|congenic strain: Tg(FCGRT)99Dcr|FCGRT|Fcgrt|Yaa
Proper citation: RRID:IMSR_JAX:025099 Copy
Issue
https://www.jax.org/strain/026016
Source Database: JAX Mice and Services
Affected Genes: urotensin 2|apolipoprotein E
Genomic Alteration: targeted mutation 1; Adel Giaid Schwertani|targeted mutation 1; University of North Carolina
Availability: sperm
Notes: gene symbol note: urotensin 2|apolipoprotein E; mutant strain|congenic strain: Uts2|Apoe
Proper citation: RRID:IMSR_JAX:026016 Copy
Issue
https://www.jax.org/strain/033761
Source Database: JAX Mice and Services
Affected Genes: gene trap ROSA 26; Philippe Soriano|NK3 homeobox 1|phosphatase and tensin homolog|Kras proto-oncogene; GTPase|
Genomic Alteration: targeted mutation 3; Hongkui Zeng|targeted mutation 4; Michael M Shen|targeted mutation 1; Hong Wu|targeted mutation 4; Tyler Jacks
Availability: live
Notes: gene symbol note: gene trap ROSA 26; Philippe Soriano|NK3 homeobox 1|phosphatase and tensin homolog|Kras proto-oncogene; GTPase|; mutant stock: Gt(ROSA)26Sor|Nkx3-1|Pten|Kras|
Proper citation: RRID:IMSR_JAX:033761 Copy
Issue
https://www.jax.org/strain/033910
Source Database: JAX Mice and Services
Affected Genes: insulin II|insulin I
Genomic Alteration: targeted mutation 1; Massimo Trucco|targeted mutation 1; Jacques Jami
Availability: sperm
Notes: gene symbol note: insulin II|insulin I; mutant strain|congenic strain: Ins2|Ins1
Proper citation: RRID:IMSR_JAX:033910 Copy
Issue
https://www.taconic.com/knockout-mouse/csmd1-targeted
Source Database: Taconic Biosciences
Affected Genes: CUB and Sushi multiple domains 1
Genomic Alteration: targeted mutation 1; Lexicon Genetics
Availability: archived
Notes: gene symbol note: CUB and Sushi multiple domains 1; mutant strain: Csmd1
Proper citation: RRID:IMSR_TAC:TF0137 Copy
Issue
https://www.jax.org/strain/030896
Source Database: JAX Mice and Services
Affected Genes: C-C motif chemokine receptor 2|C-C motif chemokine receptor 5|apolipoprotein E
Genomic Alteration: targeted mutation 1.1; Bruno Luckow|targeted mutation 3.1; Bruno Luckow|targeted mutation 1; University of North Carolina
Availability: embryo
Notes: gene symbol note: C-C motif chemokine receptor 2|C-C motif chemokine receptor 5|apolipoprotein E; mutant strain|congenic strain: Ccr2|Ccr5|Apoe
Proper citation: RRID:IMSR_JAX:030896 Copy
Issue
https://www.jax.org/strain/030892
Source Database: JAX Mice and Services
Affected Genes: C-C motif chemokine receptor 1|apolipoprotein E
Genomic Alteration: targeted mutation 1; Ji-Liang Gao|targeted mutation 1; University of North Carolina
Availability: sperm
Notes: gene symbol note: C-C motif chemokine receptor 1|apolipoprotein E; mutant strain|congenic strain: Ccr1|Apoe
Proper citation: RRID:IMSR_JAX:030892 Copy
Issue
https://www.jax.org/strain/030893
Source Database: JAX Mice and Services
Affected Genes: C-C motif chemokine receptor 2|apolipoprotein E
Genomic Alteration: targeted mutation 1.1; Bruno Luckow|targeted mutation 1; University of North Carolina
Availability: sperm
Notes: gene symbol note: C-C motif chemokine receptor 2|apolipoprotein E; mutant strain|congenic strain: Ccr2|Apoe
Proper citation: RRID:IMSR_JAX:030893 Copy
Issue
https://www.jax.org/strain/032429
Source Database: JAX Mice and Services
Affected Genes: Cre recombinase and estrogen receptor 1 fusion gene|pancreatic and duodenal homeobox 1|transformation related protein 53|transgene insertion; Douglas A Melton|Kras proto-oncogene; GTPase
Genomic Alteration: transgene insertion; Douglas A Melton|targeted mutation 1; Anton Berns|targeted mutation 4; Tyler Jacks
Availability: live
Notes: gene symbol note: Cre recombinase and estrogen receptor 1 fusion gene|pancreatic and duodenal homeobox 1|transformation related protein 53|transgene insertion; Douglas A Melton|Kras proto-oncogene; GTPase; mutant stock: cre/Esr1|Pdx1|Trp53|Tg(Pdx1-cre/Esr1*)#Dam|Kras
Proper citation: RRID:IMSR_JAX:032429 Copy
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The data sets included in this resource are published in Kravitz et al, 2012. Distinct roles for direct and indirect pathway striatal neurons in reinforcement (Nat. Neurosci).
