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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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ResearchCrossroads Funding Opportunities Database Resource Report Resource Website |
ResearchCrossroads Funding Opportunities Database (RRID:SCR_007920) | ResearchCrossroads Funding | funding resource | A database of funding opportunities from both public and private funding sources. Search by keyword and the funding opportunities matching your criteria are displayed. Click on the funding title to view the complete record. You may also add opportunities to the ResearchCrossroads database if you have registered. | research funding, research money, database | has parent organization: ResearchCrossroads | SCR_007920 | Research Crossroads Funding | 2026-09-12 12:56:58 | 0 | |||||||||
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BRIG Resource Report Resource Website 500+ mentions |
BRIG (RRID:SCR_007802) | BRIG | software resource | A cross-platform (Windows/Mac/Unix) application that can display circular comparisons between a large number of genomes, with a focus on handling genome assembly data. | bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools has parent organization: SourceForge |
DOI:10.1186/1471-2164-12-402 | OMICS_00929, biotools:brig | https://bio.tools/brig, https://sources.debian.org/src/brig/ | SCR_007802 | BLAST Ring Image Generator | 2026-09-12 12:56:57 | 561 | ||||||
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ERIC Resource Report Resource Website 500+ mentions |
ERIC (RRID:SCR_007644) | ERIC | analysis service resource, data analysis service, data or information resource, database, production service resource, service resource | ERIC is a resource of annotated enterobacterial genomes. Information is available and accessed through a open web portal uniting biological data and analysis tools. ERIC contains information on Escherichia, Shigella, Salmonella, Yersinia, and other microorgansims. ERIC has recently been moved over to PATRIC: The PATRIC BRC is now responsible for all bacterial species in the NIAID Category A-C Priority Pathogen lists for biodefense research, and pathogens causing emerging/reemerging infectious diseases. For ERIC users, we understand that the resource was valuable to your work. As such, we will be doing our very best to create a useful PATRIC resource to continue supporting your work. We realize that the transition will cause disruptions. However, it is a priority for us to work with established BRC users and communities to identify and prioritize our transition efforts. We have concentrated on the transfer of genomic data for this initial release. We anticipate adding new data, tools, and website features over the next several months. We look forward to working with you during the next 5 years., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | enterobacteria, enterobacteria pathogen, biodefense, disease bioinformatics, human disease, pathogen, pathogenic bacteria, cronobacter, enterobacter, erwinia, klebsiella, pectobacterium, photorhabdus, proteus, serratia, escherichia, shigella, salmonella, yersinia, citrobacter, FASEB list | has parent organization: Virginia Polytechnic Institute and State University; Virginia; USA | NIAID | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-02813 | http://www.ericbrc.org | SCR_007644 | Enteropathogen Resource Integration Center (ERIC), Enteropathogen Resource Integration Center | 2026-09-12 12:56:57 | 950 | |||||
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MetaCore Resource Report Resource Website 1000+ mentions |
MetaCore (RRID:SCR_008125) | data analysis software, data processing software, software application, software resource | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 17, 2022. An integrated software suite for functional analysis of experimental data. The scope of data types includes microarray and SAGE gene expression, SNPs and CGH arrays, proteomics, metabolomics, pathway analysis, Y2H and other custom interactions. MetaCore is based on a proprietary manually curated database of human protein-protein, protein-DNA and protein compound interactions, metabolic and signaling pathways and the effects of bioactive molecules in gene expression. | expression, gene, dna, interaction, metabolomics, microarray, pathway, protein, proteomic, software | is listed by: Metabolomics Workbench | THIS RESOURCE IS NO LONGER IN SERVICE. | nif-0000-20874 | http://www.genego.com/metacore.php | SCR_008125 | 2026-09-12 12:57:00 | 1182 | ||||||||
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MedGene Resource Report Resource Website 1+ mentions |
MedGene (RRID:SCR_008122) | software resource | An algorithm that generates lists of genes associated with a gene or one or more disorders. The algorithm can be used in high-throughput screening experiments, can create disease-specific micro-arrays, and can sort the results of gene profiling data. Based on the co-citations of all Medline records, MedGene can retrieve the following relationships: 1. A list of human genes associated with a particular human disease in ranking order 2. A list of human genes associated with multiple human diseases in ranking order 3. A list of human diseases associated with a particular human gene in ranking order 4. A list of human genes associated with a particular human gene in ranking order 5. The sorted gene list from other disease related high-throughput experiments, such as micro-array 6. The sorted gene list from other gene related high-throughput experiments, such as micro-array | gene, disease, human order, microarray | has parent organization: Harvard University; Cambridge; United States | nif-0000-20869 | SCR_008122 | MedGene | 2026-09-12 12:57:00 | 4 | |||||||||
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BraInSitu: A homepage for molecular neuroanatomy Resource Report Resource Website 1+ mentions |
BraInSitu: A homepage for molecular neuroanatomy (RRID:SCR_008081) | BraInSitu | atlas, data or information resource, database, experimental protocol, expression atlas, image, narrative resource | Database of detailed protocols for single and double in situ hybridization (ISH) method, probes used by Yamamori lab and others useful for studies of brain, and many photos of mammalian (mostly mouse and monkey) brains stained with various gene probes. Also includes a brain atlas of gene expression. Currently, the atlas comprises a series of un-annotated images showing the localization of a particular probe or molecule, e.g., AChE. | function, gene expression, gene, anatomical structure, brain, central nervous system, cerebral cortex, in situ hybridization, mammalian, neocortex, pcr cloning, probe, molecular neuroanatomy resource, neuroanatomy, in situ hybridization protocol | has parent organization: National Institute for Basic Biology; Okazaki; Japan | nif-0000-11633 | SCR_008081 | 2026-09-12 12:56:59 | 4 | |||||||||
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Psychology Post-doctoral Training Program, US Department of Veterans affairs, Salt Lake City, UT Resource Report Resource Website |
Psychology Post-doctoral Training Program, US Department of Veterans affairs, Salt Lake City, UT (RRID:SCR_008076) | data or information resource, funding resource, job resource, organization portal, portal, postdoctoral program resource, training resource | This web site is an overview of the post-doctoral psychology training program at the VA Salt Lake City Health Care System (VA SLC HCS). Its purpose is to help prospective psychology post-docs learn about the training and professional growth opportunities that are available. The VA Salt Lake City Health Care System postdoctoral fellowship is a full-time, 12-month continuous appointment focused on specialty training in the evaluation and treatment of veterans with Post-Traumatic Stress Disorder. Postdoctoral Fellows will be active members of two interdisciplinary treatment teams: - The PTSD Clinical Team through the Mental Health Department - The Polytrauma Team through the Physical Medicine and Rehabilitation Department. Fellows will also provide community outreach to returning veterans from Afghanistan and Iraq. Especially relevant to the VA Mental Health Strategic Plan, psychological services are provided within the complementary areas of emotional trauma (e.g., military combat, military sexual trauma), physical trauma (e.g., TBI, orthopedic injuries), substance abuse, and couples/family discord, primarily within the OEF/OIF veteran population. Sponsors: This work is funded by the US Department of Veterans Affairs, Salt Lake City. | emotional trauma, fellowship, injury, internship, military combat, military sexual trauma, opportunity, orthopedic, physical trauma, polytrauma, post-doctoral, post-traumatic stress disorder, program, psychology, substance abuse, tbi, training | nif-0000-10540 | SCR_008076 | USDVA Training Programs | 2026-09-12 12:56:59 | 0 | ||||||||||
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University of Washington Integrated Brain Project Resource Report Resource Website 1+ mentions |
University of Washington Integrated Brain Project (RRID:SCR_008075) | controlled vocabulary, data or information resource, ontology, software resource | The UW Integrated Brain Project is one project within the national Human Brain Project, a national multi-agency effort to develop informatics tools for managing the exploding amount of information that is accumulating about the human brain. The objective of the UW Integrated Brain Project effort is to organize and integrate distributed functional information about the brain around the structural information framework that is the long term goal of our work. This application therefore extends the utility of the Digital Anatomist Project by using it to organize non-structural information. The initial driving neuroscience problem that is being addressed is the management, visualization and analysis of cortical language mapping data. In recent years, advances in imaging technology such as PET and functional MRI have allowed researchers to observe areas of the cortex that are activated when the subject performs language tasks. These advances have greatly accelerated the amount of data available about human language, but have also emphasized the need to organize and integrate the sometimes contradictory sources of data, in order to develop theories about language organization. The hypothesis is that neuroanatomy is the common substrate on which the diverse kinds of data can be integrated. A result of the work done by this project is a set of software tools for generating a 3-D reconstruction of the patient''s own brain from MRI, for mapping functional data to this reconstruction, for normalizing individual anatomy by warping to a canonical brain atlas and by annotating data with terms from an anatomy ontology, for managing individual lab data in local laboratory information systems, for integrating and querying data across separate data management systems, and for visualizing the integrated results. Sponsors: This Human Brain Project research is funded jointly by the National Institute on Deafness and Other Communication Disorders, the National Institute of Mental Health, and the National Institute on Aging. | functional mri, anatomy, brain, imaging, neuroanatomy, neuroscience, open source license, pet, technology | Aging | nif-0000-10536 | SCR_008075 | UW Brain Project | 2026-09-12 12:56:59 | 1 | |||||||||
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Gladstone Institute of Neurological Disease Resource Report Resource Website 1+ mentions |
Gladstone Institute of Neurological Disease (RRID:SCR_008072) | data or information resource, job resource, organization portal, portal, training resource | GIND provides a highly interactive academic environment and state-of-the-art research facilities that are ideal for training in neuroscience and biomedical research. GIND Investigators hold university appointments at UCSF and participate in educational activities, including the teaching and training of graduate students and postdoctoral fellows. Additionally, GIND is actively engaged in efforts to translate scientific discoveries into better treatments for major diseases of the nervous system. Sponsors: Support for GIND comes from the University of California at San Francisco. | biomedical, disease, nervous system, neuroscience, research, treatment | is related to: Collaboratory of AIDS Researchers for Eradciation (CARE) | nif-0000-10522 | SCR_008072 | GIND | 2026-09-12 12:56:59 | 2 | |||||||||
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Multimodal Imaging Laboratory Resource Report Resource Website |
Multimodal Imaging Laboratory (RRID:SCR_008071) | MMIL | data or information resource, laboratory portal, organization portal, portal | An interdisciplinary group of scientists and clinicians who study the human brain using a variety of imaging, recording, and computational techniques. Their primary goal is to bridge non-invasive imaging technologies to the underlying neurophysiology of brain neuronal circuits for a better understanding of healthy human brain function, and mechanisms of disruption of this function in diseases such as Alzheimer's, epilepsy and stroke. The other goal of the MMIL is to develop and apply advanced imaging techniques to understanding the human brain and its disorders. In order to ground these methodological developments in their underlying neurobiology, invasive studies in humans and animals involving optical and micro physiological measures are also performed. These methodologies are applied to understanding normal function in sleep, memory and language, development and aging, and diseases such as dementia, epilepsy and autism. | dti, eeg, epilepsy, fmri, function, aging, alzheimer's, autism, brain, dementia, development, disease, disorder, human, mechanism, memory, microphysiological, neurobiology, neuronal circuit, neurophysiology, noninvasive methodology, pet, sleep, stroke, structural mri, language, meg, structural mri, meg |
has parent organization: University of California at San Diego; California; USA is parent organization of: Pediatric Imaging Neurocognition and Genetics |
Aging | nif-0000-10521 | SCR_008071 | 2026-09-12 12:56:59 | 0 | ||||||||
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GoatMap Database Resource Report Resource Website |
GoatMap Database (RRID:SCR_008144) | data or information resource, data repository, database, portal, service resource, storage service resource, topical portal | THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 16, 2013. This website contains information about the mapping of the caprine genome. It contains loci list, phenes list, cartography, gene list, and other sequence information about goats. This website contains 731 loci, 271 genes, and 1909 homologue loci on 112 species. It also allows users to summit their own data for Goatmap. ARK-Genomics is not-for-profit and has collaborators from all over the world with an interest in farm animal genomics and genetics. ARK-Genomics was initially set up in 2000 with a grant awarded from the BBSRC IGF (Investigating Gene Function) initiative and from core resources of the Roslin Institute to provide a laboratory for automated analysis of gene expression using state-of-the-art genomic facilities. Since then, ARK-Genomics has expanded considerably, building up considerable expertise and resources. | farm, gene, animal, caprine, cartography, genome, genomic, goat, homologue, locus, map, mapping, phene, sequence | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-20978 | SCR_008144 | GoatMap | 2026-09-12 12:57:00 | 0 | |||||||||
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Bacterial Genomes Resource Report Resource Website 10+ mentions |
Bacterial Genomes (RRID:SCR_008141) | data analysis software, data or information resource, data processing software, database, software application, software resource | This website includes a list of projects that the Sanger Institute is currently working on or completed. All projects consist of the genomic sequencing of different bacteria. Each description of the bacteria includes its classification, a description, and the types of diseases that the bacteria is likely to cause. The Sanger Institute bacterial sequencing effort is concentrated on pathogens and model organisms. Data is accessible in a number of ways; for each organism there is a BLAST server, allowing users to search the sequences with their own query and retrieve the matching contigs. Sequences can also be downloaded directly by FTP. Data is accessible in a number of ways; for each organism there is a BLAST server, allowing you to search the sequences with your own query and retrieve the matching contigs. Sequences can also be downloaded directly by FTP. The primary sequence viewer and annotation tool, Artemis is available for download. This is a portable Java program which is used extensively within the Microbial Genomes group for the analysis and annotation of sequence data from cosmids to whole genomes. The Artemis Comparison Tool (ACT) is also useful for interactive viewing of the comparisons between large and small sequences. | bacteria, bacterial, classification, description, disease, genomic, model, organism, pathogen, sequence, sequencing, model |
is listed by: 3DVC has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom |
nif-0000-20963 | SCR_008141 | Bacterial Genomes | 2026-09-12 12:57:00 | 12 | |||||||||
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Human Gut Microbiome Initiative Resource Report Resource Website |
Human Gut Microbiome Initiative (RRID:SCR_008137) | data or information resource, database, portal, topical portal | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 19,2022. Human Gut Microbiome Initiative (HGMI) seeks to provide simply annotated, deep draft genome sequences for 100 cultured representatives of the phylogenetic diversity documented by 16S rRNA surveys of the human gut microbiota. Humans are supra-organisms, composed of 10 times more microbial cells than human cells. Therefore, it seems appropriate to consider ourselves as a composite of many species - human, bacterial, and archaeal - and our genome as an amalgamation of human genes and the genes in ''our'' microbial genomes (''microbiome''). In the same sense, our metabolome can be considered to be a synthesis of co-evolved human and microbial traits. The total number of genes present in the human microbiome likely exceeds the number of our H. sapiens genes by orders of magnitude. Thus, without an understanding of our microbiota and microbiome, it not possible to obtain a complete picture of our genetic diversity and of our normal physiology. Our intestine is home to our largest collections of microbes: bacterial densities in the colon (up to 1 trillion cells/ml of luminal contents) are the highest recorded for any known ecosystem. The vast majority of phylogenetic types in the distal gut microbiota belong to just two divisions (phyla) of the domain Bacteria - the Bacteroidetes and the Firmicutes. Members of eight other divisions have also been identified using culture-independent 16S rRNA gene-based surveys. Metagenomic studies of complex microbial communities residing in our various body habitats are limited by the availability of suitable reference genomes for confident assignment of short sequence reads generated by highly parallel DNA sequencers, and by knowledge of the professions (niches) of community members. Therefore, HGMI, which represents a collaboration between Washington University''s Genome Center and its Center for Genome Sciences, seeks to provide simply annotated, deep draft genome sequences for 100 cultured representatives of the phylogenetic diversity documented by 16S rRNA surveys of the human gut microbiota. | ecosystem, firmicutes, bacterial, bacteroidetes, body, cell, diversity, genome, gut, habitat, human, metabolom, microbial, microbiome, microbiota, phylogenetic, rrna, sequence, specie, synthesis | has parent organization: Washington University in St. Louis; Missouri; USA | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-20960 | http://genome.wustl.edu/projects/athaliana/ | SCR_008137 | HGMI | 2026-09-12 12:57:00 | 0 | |||||||
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dbEST Resource Report Resource Website 100+ mentions |
dbEST (RRID:SCR_008132) | data or information resource, data repository, database, service resource, storage service resource | Database as a division of GenBank that contains sequence data and other information on single-pass cDNA sequences, or Expressed Sequence Tags, from a number of organisms. | data, sequence, single, pass, cDNA, express, tag, bio.tools, gold standard |
is listed by: Debian is listed by: bio.tools has parent organization: NCBI |
PMID:8401577 | biotools:dbest, nif-0000-20937, r3d100010648 | http://www.ncbi.nlm.nih.gov/dbEST/, https://bio.tools/dbest, https://doi.org/10.17616/R3FG8P | SCR_008132 | database Expressed Sequence Tag (EST), database Expressed Sequence Tag | 2026-09-12 12:57:00 | 186 | |||||||
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Laboratory of Molecular Neuroscience, University of Oslo Resource Report Resource Website 1+ mentions |
Laboratory of Molecular Neuroscience, University of Oslo (RRID:SCR_008097) | UiO LMN | data or information resource, portal, topical portal | A laboratory that investigates the molecular mechanisms involved in the development of acute and chronic neurodegenerative disease, with a focus on the role of glutamate excitotoxicity. It aims at unraveling the molecular basis for cell death and edema development in stroke, and explores the pathophysiology of Alzheimer's disease and temporal lobe epilepsy. The main objective of the LMN is to advance understanding of the role of glutamate, as a transmitter substance in the normal brain and as a mediator of excitotoxicity in pathological conditions such as stroke. To this end the LMN employs several vital and nonvital imaging techniques. Model systems includes organotypic slice cultures and transgenic animals. An important focus of the LMN is to explore the role of DNA damage and repair in the pathogenesis of neurodegenerative disease. LMN is also engaged in research on molecular mechanism underlying brain edema, epilepsy, and Alzheimer's disease. | epilepsy, excitotoxicity, acute, alzheimer's disease, brain, brain edema, cell death, chronic, damage, dna, glutamate, imaging, model systems, molecular, molecular mechanism, neurodegenerative disease, neuroprotective, neuroscience, repair, stroke, transmitter | has parent organization: University of Oslo; Oslo; Norway | nif-0000-11675 | SCR_008097 | University of Oslo LMN | 2026-09-12 12:57:00 | 2 | ||||||||
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University of Southern California; Los Angeles; USA Resource Report Resource Website 1+ mentions |
University of Southern California; Los Angeles; USA (RRID:SCR_008093) | USC | university | American private research university in Los Angeles, California. Founded in 1880, it is the oldest private research university in California. USC has historically educated a large number of the nation's business leaders and professionals. | private, research, university, American |
is related to: Alzheimers Disease Genetics Consortium is related to: Clinical and Translational Science Awards Consortium is related to: The Pancreatic Beta-Cell Consortium is parent organization of: Wavelet Analysis of Image Registration is parent organization of: wANNOVAR is parent organization of: Gene Aging Nexus is parent organization of: Bioscholar is parent organization of: Resource Center for Medical Ultrasonic Transducer Technology is parent organization of: Brainstorm is parent organization of: Biomedical Simulations Resource is parent organization of: Brain Operation Database is parent organization of: Karma is parent organization of: PANTHER is parent organization of: Biomedical Informatics Research Network is parent organization of: MethPipe is parent organization of: SPOT - Biological prioritization after a SNP association study is parent organization of: Bis-SNP is parent organization of: MLML is parent organization of: ENIGMA: Enhancing Neuro Imaging Genetics Through Meta-Analysis is parent organization of: lapdftext is parent organization of: Brain Architecture Management System is parent organization of: BIRN Coordinating Center is parent organization of: University of Southern California Department of Neuroscience is parent organization of: RSEG is parent organization of: University of Southern California Brain Project is parent organization of: Center for Premature Infant Health and Developement is parent organization of: Sub-Volume Thresholding Analysis is parent organization of: jViewbox is parent organization of: MultiPhase-SEG is parent organization of: LONI Java Image I/O Plugins is parent organization of: DualSurfaceMin is parent organization of: Charged Fluid Model for Brain Image Segmentation is parent organization of: CpG Island Searcher is parent organization of: Longitudinal Study of Generations is parent organization of: Biomarker Network is parent organization of: Nihon University Japanese Longitudinal Study of Aging is parent organization of: PhenoExplorer is parent organization of: Piranha is parent organization of: USC Flow Cytometry Core is parent organization of: University of Southern California School of Pharmacy Lentiviral Laboratory Core Facility is parent organization of: University of Southern California School of Pharmacy Graduate Programs is parent organization of: University of Southern California School of Pharmacy Histology Laboratory Core Facility is parent organization of: University of Southern California School of Pharmacy Translational Research Laboratory is parent organization of: University of Southern California Epigenome Center Data Production Facility is parent organization of: USC Stem Cell Core Facility is parent organization of: University of Southern California Labs and Facilities is parent organization of: USC Immune Monitoring Core Facility is parent organization of: USC Cancer Research Informatics Core is parent organization of: University of Southern California Keck School of Medicine; California; USA is parent organization of: muliAlignFree is parent organization of: GPSeq is parent organization of: CEDER is parent organization of: W3C Provenance Incubator Group Wiki is parent organization of: FadE is parent organization of: PerM is parent organization of: Clippers is parent organization of: NIMH Repository and Genomics Resources is parent organization of: CROP is parent organization of: NeuroScholar is parent organization of: GPCR Network is parent organization of: ENIGMA-DTI Pipeline is parent organization of: TomoMiner is parent organization of: MOCA is parent organization of: TopDom is parent organization of: NMF Toolbox is parent organization of: Data Archive BRAIN Initiative is parent organization of: Mouse Connectome Project is parent organization of: MethBase is parent organization of: OntoSoft is parent organization of: riborex is parent organization of: PombeX is parent organization of: University of Southern California CHLA Cellular Imaging Core Facility is parent organization of: University of Southern California CHLA Extracellular Vesicle Core Facility is parent organization of: ReproRehab Research Education Course is parent organization of: Global Alzheimers Association Interaction Network is parent organization of: USC-SIPI Image Database has organization facet: Neurodevelopmental MRI Database |
grid.42505.36, Wikidata:Q4614, ISNI:0000 0001 2156 6853, Crossref funder ID:100006034, nlx_24939 | https://ror.org/03taz7m60 | SCR_008093 | University of Southern California | 2026-09-12 12:57:00 | 8 | |||||||
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University of West Bohemia; Pilsen; Czech Republic Resource Report Resource Website |
University of West Bohemia; Pilsen; Czech Republic (RRID:SCR_008203) | UWB | university | The University of West Bohemia is a university in Pilsen, Czech Republic. It was founded in 1991 and consists of nine faculties. | is parent organization of: EEGbase | nlx_50579 | SCR_008203 | 2026-09-12 12:57:01 | 0 | ||||||||||
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BiQAnalyzer HT Resource Report Resource Website 10+ mentions |
BiQAnalyzer HT (RRID:SCR_008045) | BiQAnalyzer HT | software resource | Software that currently allows to process an amount of bisulfite sequencing reads obtained in one or several bisulfite sequencing experiments. | is listed by: OMICtools | OMICS_00631 | SCR_008045 | 2026-09-12 12:56:59 | 12 | ||||||||||
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Tulane National Biomedical Research Center Resource Report Resource Website 500+ mentions |
Tulane National Biomedical Research Center (RRID:SCR_008167) | TNPRC | data or information resource, disease-related portal, organization portal, portal, topical portal | Center focused on understanding human health problems, including infectious diseases that require the use of nonhuman primates to develop diagnostics, therapeutics and preventive strategies. Primary research interests include developing vaccines, treatments and diagnostic tools for infectious diseases such as AIDS, tuberculosis, CMV, COVID-19, Lyme disease, and malaria. TNPRC has both biosafety level 2 and biosafety level 3 laboratories facilities to accommodate various research needs, and is the only National Primate Research Center with Regional Biosafety Laboratory. | NPRC, NPRC Consortium, ORIP, primate research, |
is listed by: National Primate Research Center Consortium has parent organization: Tulane University; Louisiana; USA |
NIH Office of the Director P51 OD011104; NIH Office of the Director U42 OD010568; NIH Office of the Director U42 OD024282 |
nif-0000-24360 | https://orip.nih.gov/comparative-medicine/programs/vertebrate-models | SCR_008167 | Tulane National Primate Research Center | 2026-09-12 12:57:00 | 866 | ||||||
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Interaction Proteome Project Resource Report Resource Website 1+ mentions |
Interaction Proteome Project (RRID:SCR_008043) | IPP | data or information resource, portal, simulation software, software application, software resource, topical portal | THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 28, 2013. (URL is no longer valid) A platform for high-throughput proteomic analysis. Major objectives of IPP include the establishment of a broadly applicable platform of routine methods for the analysis of protein interaction networks in bio-medical research. A multidisciplinary approach will address; * their validation by cell biological, biochemical and biophysical methods. * their collection in a new type of public database. * their exploitation and use for in silico simulations of protein-interaction networks. The innovations generated in IPP will provide the basis for an efficient analysis and systems modeling of fundamental biological processes in health and disease. It will develop novel technology, including a high-end mass spectrometer with extremely large dynamic range, high-density peptide arrays, and improved visualization technology for light and electron microscopy. Additionally, the novel technologies will be validated with selected model systems of high relevance to medicine and biotechnology. Extensive bioinformatics support is a key element in the project to cope with the massive increase in experimental data on protein interactions obtained using the novel technologies. In particular, the efficient integration of disparate data sets represents a key challenge in proteomics and functional genomics. Therefore, the consortium includes the creator of the only European protein-interactions database, MINT. The multi-disciplinary efforts required in the scientific program of IPP are organized into four sub-projects (SP): * SP1: Tools for interaction analysis - SP1 is dedicated to the development of innovative proteomics technology to map protein-interaction networks and their cellular topology for the interaction analyses in SP2 and SP3. * SP2: Identification of interaction partners for protein domains - SP2 will generate (high throughput) data for important protein-protein interactions defined by bioinformatics and biomedical interest and by SP3, utilizing technology developed in SP1. * SP3: Functional analysis of interactions - SP3 focuses on the validation of technologies and tools developed in SP1. It will perform functional analyses of protein-interactions in medically and biochemically relevant prokaryotic and eukaryotic (mammalian) model systems. * SP4: Interactome database and modelling - SP4 provides the required bioinformatics infrastructure for the project, comprising the improvement of the public MINT database for the collection and dissemination of the interactome data; modelling and simulation of protein-interaction networks characterised in SP2 and SP3; and the dissemination of the technology developments to the scientific community. | electron, eukaryotic, biochemical, bioinformatics, biological, biomedical, biophysical, biotechnology, cell, development, disease, domain, genomics, health, interaction, light, mammalian, map, mass spectrometer, medicine, microscopy, model, modeling, network, peptide array, prokayotic, protein interaction, proteome, proteomics, silico, simulation, system, technology, tool, protein interaction | has parent organization: Max Planck Institute of Biochemistry; Martinsried; Germany | European Union | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-10259 | SCR_008043 | Interaction Proteome | 2026-09-12 12:56:59 | 1 |
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The data sets included in this resource are published in Kravitz et al, 2012. Distinct roles for direct and indirect pathway striatal neurons in reinforcement (Nat. Neurosci).
