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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Discontinued
https://web.expasy.org/cellosaurus/CVCL_T734
Organism: Homo sapiens (Human)
Disease: Esophageal squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_T734 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_V349
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Discontinued: Takara/Clontech; Catalog number 630908., Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16.
Proper citation: RRID:CVCL_V349 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_M624
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Caution: Not to be confused with cell line HEK293 (Cellosaurus=CVCL_0045)., Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=4469665; PubMed=4864103; PubMed=20143388). Originally thought to originate from an embryonic kidney..
Proper citation: RRID:CVCL_M624 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_KS31
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Discontinued: Takara/Clontech; Catalog number 630903., Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
Proper citation: RRID:CVCL_KS31 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_2930
Organism: Homo sapiens (Human)
Disease: Endometrial adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: MD Anderson Cell Lines Project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2930 Copy
Contaminated Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_2926
Organism: Homo sapiens (Human)
Disease: Endometrial adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese., Problematic cell line: Contaminated. HEC-155 and HEC-180 have been shown to be identical (PubMed=20143388). Originally thought to originate from a 56 year old female patient with primary endometrial cancer..
Proper citation: JCRB Cat# JCRB1127, RRID:CVCL_2926 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_2928
Organism: Homo sapiens (Human)
Disease: Endometrial adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: MD Anderson Cell Lines Project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2928 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0294
Organism: Homo sapiens (Human)
Disease: Type II endometrial adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: MD Anderson Cell Lines Project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0294 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_2931
Organism: Homo sapiens (Human)
Disease: Endometrial endometrioid adenocarcinoma, variant with squamous differentiation
Category: Cancer cell line
Comments: Population: Japanese., Part of: MD Anderson Cell Lines Project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2931 Copy
Contaminated Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_2926
Organism: Homo sapiens (Human)
Disease: Endometrial adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese., Problematic cell line: Contaminated. HEC-155 and HEC-180 have been shown to be identical (PubMed=20143388). Originally thought to originate from a 56 year old female patient with primary endometrial cancer..
Proper citation: JCRB Cat# NIHS0397, RRID:CVCL_2926 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_KU43
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Discontinued: Takara/Clontech; Catalog number 631149., Discontinued: Takara/Clontech; Catalog number 630931., Characteristics: Transfected with an advanced reverse tetracycline-controlled transactivator (rtTA2(S)-M2), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
Proper citation: RRID:CVCL_KU43 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_RU21
Organism: Homo sapiens (Human)
Category: Somatic stem cell
Comments: Characteristics: Undergoes chondrogenesis in a progenitor with markers of head and limb mesenchyme and low levels of hypertrophic marker COL10A1., From: ESI BIO - BioTime, Inc. (ES Cell International); Alameda; USA., Group: Patented cell line.
Proper citation: RRID:CVCL_RU21 Copy
Misidentified/Contaminated
https://web.expasy.org/cellosaurus/CVCL_RQ51
Organism: Homo sapiens (Human)
Disease: Melanoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Resistant Cancer Cell Line (RCCL) collection., Problematic cell line: Misidentified/contaminated. Parent cell line (Mel-Ho) was reported to be isogenic with LCL-Ho (Cellosaurus=CVCL_1868) but it does not have the same STR profile..
Proper citation: RRID:CVCL_RQ51 Copy
Misidentified/Contaminated
https://web.expasy.org/cellosaurus/CVCL_RS67
Organism: Homo sapiens (Human)
Disease: Melanoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Resistant Cancer Cell Line (RCCL) collection., Problematic cell line: Misidentified/contaminated. Parent cell line (Mel-Ho) was reported to be isogenic with LCL-Ho (Cellosaurus=CVCL_1868) but it does not have the same STR profile..
Proper citation: RRID:CVCL_RS67 Copy
Possibly Contaminated
https://web.expasy.org/cellosaurus/CVCL_UI43
Organism: Homo sapiens (Human)
Category: Hybrid cell line
Comments: Problematic cell line: Contaminated. Parent cell line (MGC-803) seems to be a derivative of HeLa and probably of a gastric cancer cell..
Proper citation: RRID:CVCL_UI43 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_1T53
Organism: Mus musculus (Mouse)
Category: Embryonic stem cell
Proper citation: RCB Cat# AES0004, RRID:CVCL_1T53 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_J844
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: RRID:CVCL_J844 Copy
Misidentified
https://web.expasy.org/cellosaurus/CVCL_A0GW
Organism: Sus scrofa (Pig)
Category: Spontaneously immortalized cell line
Comments: Virology: Susceptible to infection by foot-and-mouth disease virus (PubMed=34092457)., Virology: Combined treatment of the parent cell line with BVDV NS5A siRNA, interferon alpha and ribavirin has cured the cell line from bovine viral diarrhea virus (BVDV) infection (PubMed=34092457)., Problematic cell line: Misidentified. Grand-parent cell line (LF-BK) was originally thought to be of bovine origin but originates from pig..
Proper citation: RRID:CVCL_A0GW Copy
Possibly Contaminated
https://web.expasy.org/cellosaurus/CVCL_VG42
Organism: Homo sapiens (Human)
Category: Hybrid cell line
Comments: Problematic cell line: Contaminated. Parent cell line (MGC-803) seems to be a derivative of HeLa and probably of a gastric cancer cell..
Proper citation: RRID:CVCL_VG42 Copy
Possibly Contaminated
https://web.expasy.org/cellosaurus/CVCL_5334
Organism: Homo sapiens (Human)
Category: Hybrid cell line
Comments: Miscellaneous: Formerly the CCRID database had 2 entries describing this cell line (3111C0001CCC000227, 3131C0001000700084). They were one of the sources for the STR profile of this entry., Problematic cell line: Contaminated. Seems to be an hybrid of HeLa and probably of a gastric cancer cell from an Asian individual. The STR profile is highly similar to that of HeLa yet shows some specific differences that suggest it is an hybrid cell line (PubMed=37543987; PubMed=38079103). Was originally thought to originate from a 53 year old male patient suffering from a poorly differentiated gastric mucinous adenocarcinoma..
Proper citation: RRID:CVCL_5334 Copy
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The data sets included in this resource are published in Kravitz et al, 2012. Distinct roles for direct and indirect pathway striatal neurons in reinforcement (Nat. Neurosci).
