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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Misidentified Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4226
Organism: Anguilla japonica (Japanese eel)
Category: Spontaneously immortalized cell line
Comments: Problematic cell line: Misidentified. Originally thought to be of tilapia origin (Oreochromis niloticus) but found to be from eel (DOI=10.1007/s12562-018-1215-4; RCB). Is probably identical to Hepa-E1.., Group: Fish cell line.
Proper citation: RCB Cat# RCB1156, RRID:CVCL_4226 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_9720
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Miscellaneous: This cell line is exclusively produced and controlled by Biopredic International and owned by Inserm. BioPredic sells undifferentiated cell line (HPR101) that can be expanded, passaged, and frozen in-house to prepare a cell bank and differentiated ready-to-use cells, HPR116 (Cellosaurus=CVCL_WL73) that can be used immediately or in a few days after thawing, as a single-use disposable product (Biopredic)., Anecdotal: The 'RG' in the cell name stands for 'Rumin' and 'Gripon', the two scientists that were influential in the establishment of this cell line., Characteristics: Cell line main applications are sugar and lipid metabolism, physiopathology; drug metabolism and toxicology and viral infection., Characteristics: Can be induced to differentiate into hepatocyte-like cells by exposure to DMSO., Group: Patented cell line.
Proper citation: RRID:CVCL_9720 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_DC15
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Acts through the activation of a luciferase reporter gene which is under the control of dioxin-response elements (DREs) from mouse Cyp1a1 gene., Biotechnology: Can be used for bioassays to detect dioxin/TCDD-like compounds., Group: Patented cell line.
Proper citation: RRID:CVCL_DC15 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_M177
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Virology: Inducibly expresses a hepatitis B virus (HBV) genome under the control of a tet operator/CMV promoter. Upon removal of tetracycline the cell line produces viral RNA and secrete virus-like particles into the supernatant., Biotechnology: Used in a bioassay that permits the large-scale screening of compound libraries for inhibitors of HBV replication., Population: Caucasian., Group: Patented cell line.
Proper citation: RRID:CVCL_M177 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_TZ61
Organism: Homo sapiens (Human)
Disease: Adult hepatocellular carcinoma
Category: Cancer cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: RRID:CVCL_TZ61 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_5I95
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_5I95 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_8560
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_8560 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4525
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: RRID:CVCL_4525 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_3702
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Caution: Indicated as originating from a 25 year old male in ATCC, but said to be derived from autopsy specimen from a 74 year old male., Population: African American., Group: Patented cell line.
Proper citation: RRID:CVCL_3702 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_3702
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Caution: Indicated as originating from a 25 year old male in ATCC, but said to be derived from autopsy specimen from a 74 year old male., Population: African American., Group: Patented cell line.
Proper citation: ATCC Cat# CRL-2692, RRID:CVCL_3702 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_C495
Organism: Mus musculus (Mouse)
Category: Hybridoma
Proper citation: RRID:CVCL_C495 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3516
Organism: Homo sapiens (Human)
Disease: Pituitary gland adenoma
Category: Transformed cell line
Proper citation: RRID:CVCL_3516 Copy
Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_3716
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Senescence: Capable of at least 29 PDL (ATCC=CRL-2598)., Part of: Wistar Institute Special Collection vascular cell lines.
Proper citation: ATCC Cat# CRL-2598, RRID:CVCL_3716 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_UJ10
Organism: Homo sapiens (Human)
Disease: Childhood T acute lymphoblastic leukemia
Category: Cancer cell line
Comments: Population: Japanese., Problematic cell line: Contaminated. Parent cell line (HPB-MLT) has been shown to be a HPB-ALL derivative..
Proper citation: RRID:CVCL_UJ10 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_8446
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Caution: Was reported to derive from HPC-36 (Cellosaurus=CVCL_M169)., Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=20143388). Originally thought to originate from a prostate carcinoma..
Proper citation: RRID:CVCL_8446 Copy
Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_7959
Organism: Homo sapiens (Human)
Disease: Childhood T acute lymphoblastic leukemia
Category: Cancer cell line
Comments: Population: Japanese., Problematic cell line: Contaminated. Shown to be a HPB-ALL derivative (PubMed=12592342; PubMed=20143388). Originally thought to originate from a 62 year old female patient with a T-cell lymphoid malignancy..
Proper citation: RRID:CVCL_7959 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3717
Organism: Mus musculus (Mouse)
Category: Finite cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: RRID:CVCL_3717 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_3710
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Senescence: Senesces at ~22 PDL (ATCC=CRL-2014)., Population: Caucasian.
Proper citation: RRID:CVCL_3710 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_3710
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Senescence: Senesces at ~22 PDL (ATCC=CRL-2014)., Population: Caucasian.
Proper citation: KCLB Cat# 22014, RRID:CVCL_3710 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_AE98
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: From: Wellcome Trust Sanger Institute; Hinxton; United Kingdom., From: Cambridge BioResource; Cambridge; United Kingdom.
Proper citation: EBiSC Cat# WTSIi054-B, RRID:CVCL_AE98 Copy
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The data sets included in this resource are published in Kravitz et al, 2012. Distinct roles for direct and indirect pathway striatal neurons in reinforcement (Nat. Neurosci).
