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URL: http://www.wormbase.org/db/get?name=WBStrain00029260
Proper Citation: RRID:WB-STRAIN:WBStrain00029260
Description: Caenorhabditis elegans with name drSi4 II; unc-119(ed3) III. from WB.
Species: Caenorhabditis elegans
Synonyms: drSi4 II; unc-119(ed3) III.
Notes: drSi4 [vha-6p::3XFLAG::pgp-3/CFTR(delta F508)::mCherry::unc-54 3'UTR] II. Superficially wild-type with mCherry expression only in the intestine with significantly diminished expression as compared to drSi2. Single copy integration of the vha-6 promoter driving the PGP-3 protein with an N-terminal 3XFLAG tag and a C-terminal mCherry tag. Amino acids 476-484 of PGP-3 have been replaced with amino acids 501-509 of human CFTR with F508 deleted (TIKENII_G). Transgene was inserted at the ttTi5605 locus on LGII and verified to be a single copy insertion by long range PCR across the genomic locus. Reference: He L, et al. Dis Model Mech. 2012 Nov;5(6):930-9.
Affected Gene: WBGene00006843(unc-119)
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Source: Integrated Animals
Source Database: WormBase (WB)
The data sets included in this resource are published in Kravitz et al, 2012. Distinct roles for direct and indirect pathway striatal neurons in reinforcement (Nat. Neurosci).
