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URL: https://www.jax.org/strain/035169
Proper Citation: RRID:IMSR_JAX:035169
Description:
Mus musculus with name B6.Cg-Krastm4Tyj Apc
Species: Mus musculus
Synonyms: KPC:APC
Notes: gene symbol note: caudal type homeobox 2|Cre recombinase and estrogen receptor 1 (human) fusion gene|Kras proto-oncogene; GTPase|transgene insertion 752; Eric Fearon|APC; WNT signaling pathway regulator; mutant strain|congenic strain: CDX2|cre/ERT2|Kras|Tg(CDX2-cre/ERT2)752Erf|Apc
Affected Gene: caudal type homeobox 2|Cre recombinase and estrogen receptor 1 (human) fusion gene|Kras proto-oncogene; GTPase|transgene insertion 752; Eric Fearon|APC; WNT signaling pathway regulator
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Issue
Warning. Researchers have noted that this genotype does not sufficiently model human acute myeloid leukemia.
Source: International Mouse Strain Resource (RRID:SCR_001526)
Description: Database of mouse strains and stocks available worldwide, that will assist international research community in finding mouse resources they need, including inbred, mutant, and genetically engineered mice. IMSR is multi institutional international collaboration supporting use of mouse as model system for studying human biology and disease. IMSR began with initial collaboration between Mouse Genome Informatics (MGI) group at Jackson Laboratory and Medical Research Council Mammalian Genetics Unit at Harwell. Additional institutions and collaborators are now contributing mouse resource information to IMSR. Data content found in IMSR is as it was supplied by data provider sites. You are encouraged to participate in making this database as complete as possible for all worldwide mouse strain resources. If you or your institution hold mice, cryopreserved gametes or embryos, or ES cell lines that you distribute to other researchers, contributing information about them to IMSR catalog will make them more widely known.
URL: http://www.findmice.org/index.jsp
Source Database: JAX Mice and Services