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URL: https://www.jax.org/strain/000664
Proper Citation: RRID:IMSR_JAX:000664
Description: Mus musculus with name C57BL/6J from IMSR.
Species: Mus musculus
Synonyms: B6. B6J. Black 6. C57 Black. C57BL/6JAnu
Notes: gene symbol note: microwave induced increase in complement receptor B cells|aryl-hydrocarbon receptor|arylalkylamine N-acetyltransferase|glucose homeostasis QTL 1|forebrain weight 1|beta-2 microglobulin|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|MX dynamin-like GTPase 1|glucose homeostasis QTL 2|nuclear encoded tRNA arginine 5 (anticodon TCT)|CD5 antigen|latent transforming growth factor beta binding protein 4|forebrain weight 2|NLR family; pyrin domain containing 12|purinergic receptor P2X; ligand-gated ion channel; 7|cadherin related 23 (otocadherin)|hemoglobin beta chain complex|nicotinamide nucleotide transhydrogenase|annexin A6|gamma-aminobutyric acid type A receptor subunit alpha 2|cytochrome c oxidase subunit 7A2 like|glucose homeostasis QTL 3; inbred strain: Micrl|Ahr|Aanat|Gluchos1|Fbrwt1|B2m|Apobec3|Mx1|Gluchos2|n-TRtct5|Cd5|Ltbp4|Fbrwt2|Nlrp12|P2rx7|Cdh23|Hbb|Nnt|Anxa6|Gabra2|Cox7a2l|Gluchos3
Affected Gene: microwave induced increase in complement receptor B cells|aryl-hydrocarbon receptor|arylalkylamine N-acetyltransferase|glucose homeostasis QTL 1|forebrain weight 1|beta-2 microglobulin|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|MX dynamin-like GTPase 1|glucose homeostasis QTL 2|nuclear encoded tRNA arginine 5 (anticodon TCT)|CD5 antigen|latent transforming growth factor beta binding protein 4|forebrain weight 2|NLR family; pyrin domain containing 12|purinergic receptor P2X; ligand-gated ion channel; 7|cadherin related 23 (otocadherin)|hemoglobin beta chain complex|nicotinamide nucleotide transhydrogenase|annexin A6|gamma-aminobutyric acid type A receptor subunit alpha 2|cytochrome c oxidase subunit 7A2 like|glucose homeostasis QTL 3
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Issue
Warning this mouse may be epileptogenic. The cause seems to be that the GABAA receptor is expressed at very low levels compared to other mouse strains including the C57BL/6N, according to Hawkins (2016) and Mulligan (2019).
Source: Integrated Animals
Source Database: JAX Mice and Services
The data sets included in this resource are published in Kravitz et al, 2012. Distinct roles for direct and indirect pathway striatal neurons in reinforcement (Nat. Neurosci).
