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URL: http://clip.med.yale.edu/SHM
Proper Citation: Models of SHM Targeting and Substitution (RRID:SCR_005250)
Description: A targeting model that defines where mutations occur (by specifying the relative rates at which DNA motifs in the Ig sequence are mutated), and a nucleotide substitution model that defines the resulting mutation (by specifying the probability of each base mutating to each of the other three possibilities as a function of the surrounding bases).
Abbreviations: S5F
Synonyms: S5F - Models of SHM Targeting and Substitution, Models of SHM Targeting and Substitution
Resource Type: data or information resource, data set
Defining Citation: PMID:24298272
Keywords: somatic hypermutation, substitution, targeting, aid, b cell, affinity maturation, immunoglobulin, mutability, mutation, model, targeting model, nucleotide substitution model
Availability: Creative Commons Attribution-NonCommercial-ShareAlike License, v3 Unported
Resource Name: Models of SHM Targeting and Substitution
Resource ID: SCR_005250
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Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400
The data sets included in this resource are published in Kravitz et al, 2012. Distinct roles for direct and indirect pathway striatal neurons in reinforcement (Nat. Neurosci).
