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URL: http://bioconductor.org/packages/2.13/bioc/html/sSeq.html
Proper Citation: sSeq (RRID:SCR_001719)
Description: Software package to discover the genes that are differentially expressed between two conditions in RNA-seq experiments. Gene expression is measured in counts of transcripts and modeled with the Negative Binomial (NB) distribution using a shrinkage approach for dispersion estimation. The method of moment (MM) estimates for dispersion are shrunk towards an estimated target, which minimizes the average squared difference between the shrinkage estimates and the initial estimates. The exact per-gene probability under the NB model is calculated, and used to test the hypothesis that the expected expression of a gene in two conditions identically follow a NB distribution.
Abbreviations: sSeq
Synonyms: sSeq - Shrinkage estimation of dispersion in Negative Binomial models for RNA-seq experiments with small sample size
Resource Type: software resource
Defining Citation: PMID:23589650
Keywords: rna-seq, differential expression
Availability: Free, Available for download, Freely available
Resource Name: sSeq
Resource ID: SCR_001719
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Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400
The data sets included in this resource are published in Kravitz et al, 2012. Distinct roles for direct and indirect pathway striatal neurons in reinforcement (Nat. Neurosci).
