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NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism.

K Chrysovergis | X Wang | J Kosak | S-H Lee | J S Kim | J F Foley | G Travlos | S Singh | S J Baek | T E Eling
International journal of obesity (2005) | 2014

Obesity is a major health problem associated with high morbidity and mortality. NSAID-activated gene (NAG-1) is a TGF-β superfamily member reported to alter adipose tissue levels in mice. We investigated whether hNAG-1 acts as a regulator of adiposity and energy metabolism.

Pubmed ID: 24531647

Research resources used in this publication

None found

Antibodies used in this publication

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Associated grants

  • Agency: Intramural NIH HHS, United States
    Id: Z01 ES010016
  • Agency: Intramural NIH HHS, United States
    Id: ZIA ES010016-15

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Intramural Research Program (tool)

RRID:SCR_012734

A research program of the NIA which focuses on neuroscience, aging biology, and translational gerontology. The central focus of the program's research is understanding age-related changes in physiology and the ability to adapt to environmental stress, and using that understanding to develop insight about the pathophysiology of age-related diseases. The IRP webpage provides access to other NIH resources such as the Biological Biochemical Image Database, the Bioinformatics Portal, and the Baltimore Longitudinal Study of Aging.

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Fitzgerald Industries International (tool)

RRID:SCR_003237

Commercial organization that supplies antibodies, proteins, ELISA kits, serum, and plasma to the research community.

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BioRad Helios Gene Delivery System (tool)

RRID:SCR_019723

Handheld gene delivery system that provides direct transfection into a range of targets in vivo. It uses adjustable low pressure helium pulse to sweep DNA, RNA, or biomaterial coated gold microcarriers from a plastic cartridge directly into target cells.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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B16-F10 (tool)

RRID:CVCL_0159

Cell line B16-F10 is a Cancer cell line with a species of origin Mus musculus (Mouse)

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